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Research Articles

Cyclodextrin–poloxamer aggregates as nanocarriers in eye drop formulations: dexamethasone and amphotericin B

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Pages 1446-1454 | Received 06 Sep 2015, Accepted 31 Dec 2015, Published online: 16 Feb 2016

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Hay Man Saung Hnin Soe, Suppakan Sripetch, Thorsteinn Loftsson, Einar Stefánsson & Phatsawee Jansook. (2022) Effect of Soluplus® on γ-cyclodextrin solubilization of irbesartan and candesartan and their nanoaggregates formation. Pharmaceutical Development and Technology 27:1, pages 9-18.
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Kengo Banshoya, Yoshiharu Kaneo, Makoto Shirakawa, Yuhzo Hieda, Aoi Machida, Masatoshi Ohnishi & Tetsuro Tanaka. (2023) Preparation and in vitro evaluation of amphotericin B-loaded nano-formulations for both intravenous and ophthalmic administration using 3-aminophenylboronic acid-conjugated styrene-maleic acid copolymers. Journal of Drug Delivery Science and Technology 90, pages 105176.
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Shuaishuai Liu, Tolulope Ale, Victor Kehinde, Temitope Ale, Heuy-Ching Wang & Erin Lavik. (2023) Polyester Nanoparticles and Polyurethane Nanocapsules Deliver Pirfenidone To Reduce Fibrosis and Scarring. ACS Biomaterials Science & Engineering 9:6, pages 3348-3355.
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Xiaolin Li, Xunchan Jiang, Xiaolei Zhou, Yanju Cheng & Feng Cao. (2023) Development of dexamethasone suspension eye drops: A comparative investigation of ternary and quaternary cyclodextrin aggregates. Journal of Drug Delivery Science and Technology 82, pages 104383.
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Ivana Pantelić, Tanja Ilić, Ines Nikolić & Snežana Savić. (2023) Self-assembled carriers as drug delivery systems: Current characterization challenges and future prospects. Arhiv za farmaciju 73:5, pages 404-422.
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Phatsawee Jansook & Thorsteinn Loftsson. (2022) Self-assembled γ-cyclodextrin as nanocarriers for enhanced ocular drug bioavailability. International Journal of Pharmaceutics 618, pages 121654.
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Phyo Darli Maw, Prompong Pienpinijtham, Patamaporn Pruksakorn & Phatsawee Jansook. (2022) Cyclodextrin-based Pickering nanoemulsions containing amphotericin B: Part II. Formulation, antifungal activity, and chemical stability. Journal of Drug Delivery Science and Technology 69, pages 103174.
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Manisha Prajapati & Thorsteinn Loftsson. (2022) Stabilization and solubilization of difluprednate in aqueous cyclodextrin solution and its characterization for ophthalmic delivery. Journal of Drug Delivery Science and Technology 69, pages 103106.
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Kengo Banshoya, Chiaki Fujita, Yuka Hokimoto, Masatoshi Ohnishi, Atsuko Inoue, Tetsuro Tanaka & Yoshiharu Kaneo. (2021) Amphotericin B nanohydrogel ocular formulation using alkyl glyceryl hyaluronic acid: Formulation, characterization, and in vitro evaluation. International Journal of Pharmaceutics 610, pages 121061.
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Tarsila R. Arruda, Clara S. Marques & Nilda F. F. Soares. (2021) Native Cyclodextrins and Their Derivatives as Potential Additives for Food Packaging: A Review. Polysaccharides 2:4, pages 825-842.
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Virginia Aiassa, Claudia Garnero, Marcela R. Longhi & Ariana Zoppi. (2021) Cyclodextrin Multicomponent Complexes: Pharmaceutical Applications. Pharmaceutics 13:7, pages 1099.
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Blanca Lorenzo-Veiga, Carmen Alvarez-Lorenzo, Thorsteinn Loftsson & Hakon Hrafn Sigurdsson. (2021) Age-related ocular conditions: Current treatments and role of cyclodextrin-based nanotherapies. International Journal of Pharmaceutics 603, pages 120707.
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Ulrich Schubert, Andreas Winter & George Newkome. 2021. Supramolecular Polymers and Assemblies. Supramolecular Polymers and Assemblies 343 386 .
Thomas Swift, Emily Caseley, Abbigail Pinnock, Joanna Shepherd, Nagaveni Shivshetty, Prashant Garg, C. W. Ian Douglas, Sheila MacNeil & Stephen Rimmer. (2021) Branched amphotericin functional poly( N - iso propyl acrylamide): an antifungal polymer . Royal Society Open Science 8:1, pages 201655.
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Raul Diaz-Salmeron, Balthazar Toussaint, Nicolas Huang, Etienne Bourgeois Ducournau, Gabriel Alviset, Sophie Goulay Dufaÿ, Hervé Hillaireau, Amélie Dufaÿ Wojcicki & Vincent Boudy. (2021) Mucoadhesive Poloxamer-Based Hydrogels for the Release of HP-β-CD-Complexed Dexamethasone in the Treatment of Buccal Diseases. Pharmaceutics 13:1, pages 117.
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Hay ManSaung Hnin Soe, Supakarn Chamni, Panupong Mahalapbutr, Napat Kongtaworn, Thanyada Rungrotmongkol & Phatsawee Jansook. (2020) The investigation of binary and ternary sulfobutylether-β-cyclodextrin inclusion complexes with asiaticoside in solution and in solid state. Carbohydrate Research 498, pages 108190.
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Malwina Lachowicz, Andrzej Stańczak & Michał Kołodziejczyk. (2020) Characteristic of Cyclodextrins: Their Role and Use in the Pharmaceutical Technology. Current Drug Targets 21:14, pages 1495-1510.
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Ruslan Kashapov, Gulnara Gaynanova, Dinar Gabdrakhmanov, Denis Kuznetsov, Rais Pavlov, Konstantin Petrov, Lucia Zakharova & Oleg Sinyashin. (2020) Self-Assembly of Amphiphilic Compounds as a Versatile Tool for Construction of Nanoscale Drug Carriers. International Journal of Molecular Sciences 21:18, pages 6961.
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Rebeca González-Louzao, Carmen Lucas-Abellán, Horacio Pérez-Sánchez, José Pedro Cerón-Carrasco, José Antonio Gabaldón, Santiago López-Miranda, María Josefa Yáñez-Gascón, Manuel Asín-Llorca & Estrella Núñez-Delicado. (2020) Encapsulation of finasteride with native and modified γ-cyclodextrins. Extensive characterization of the complexes. International Journal of Pharmaceutics 587, pages 119619.
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Phatsawee Jansook, Phyo Darli Maw, Hay Man Saung Hnin Soe, Ravinsinee Chuangchunsong, Kitisak Saiborisuth, Nawaporn Payonitikarn, Rinrapas Autthateinchai & Patamaporn Pruksakorn. (2020) Development of amphotericin B nanosuspensions for fungal keratitis therapy: effect of self-assembled γ-cyclodextrin. Journal of Pharmaceutical Investigation 50:5, pages 513-525.
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Roseline Mazet, Josias B. G. Yaméogo, Denis Wouessidjewe, Luc Choisnard & Annabelle Gèze. (2020) Recent Advances in the Design of Topical Ophthalmic Delivery Systems in the Treatment of Ocular Surface Inflammation and Their Biopharmaceutical Evaluation. Pharmaceutics 12:6, pages 570.
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Cristina Di Donato, Rosa Iacovino, Carla Isernia, Gaetano Malgieri, Angela Varela-Garcia, Angel Concheiro & Carmen Alvarez-Lorenzo. (2020) Polypseudorotaxanes of Pluronic® F127 with Combinations of α- and β-Cyclodextrins for Topical Formulation of Acyclovir. Nanomaterials 10:4, pages 613.
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Pitsiree Praphanwittaya, Phennapha Saokham, Phatsawee Jansook & Thorsteinn Loftsson. (2020) Aqueous solubility of kinase inhibitors: II the effect of hexadimethrine bromide on the dovitinib/γ-cyclodextrin complexation. Journal of Drug Delivery Science and Technology 55, pages 101463.
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Pitsiree Praphanwittaya, Phennapha Saokham, Phatsawee Jansook & Thorsteinn Loftsson. (2020) Aqueous solubility of kinase inhibitors: I the effect of hydrophilic polymers on their γ-cyclodextrin solubilization. Journal of Drug Delivery Science and Technology 55, pages 101462.
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Prit Lakhani, Akash Patil, Kai-Wei Wu, Corinne Sweeney, Siddharth Tripathi, Bharathi Avula, Pranjal Taskar, Shabana Khan & Soumyajit Majumdar. (2019) Optimization, stabilization, and characterization of amphotericin B loaded nanostructured lipid carriers for ocular drug delivery. International Journal of Pharmaceutics 572, pages 118771.
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Tianhe Huang, Qianqian Zhao, Yan Su & Defang Ouyang. (2019) Investigation of molecular aggregation mechanism of glipizide/cyclodextrin complexation by combined experimental and molecular modeling approaches. Asian Journal of Pharmaceutical Sciences 14:6, pages 609-620.
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Blanca Lorenzo-Veiga, Hakon Sigurdsson & Thorsteinn Loftsson. (2019) Nepafenac-Loaded Cyclodextrin/Polymer Nanoaggregates: A New Approach to Eye Drop Formulation. Materials 12:2, pages 229.
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Shery Jacob & Anroop B. Nair. (2018) Cyclodextrin complexes: Perspective from drug delivery and formulation. Drug Development Research 79:5, pages 201-217.
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Meng-Ke Zhang, Yuan Lyu, Xiao Zhu, Jin-Peng Wang, Zheng-Yu Jin & Ganesan Narsimhan. (2018) Enhanced solubility and antimicrobial activity of alamethicin in aqueous solution by complexation with γ-cyclodextrin. Journal of Functional Foods 40, pages 700-706.
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Federica Bianchi, Monica Mattarozzi, Nicolò Riboni, Paolo Mora, Stefano A. Gandolfi & Maria Careri. (2017) A rapid microextraction by packed sorbent − liquid chromatography tandem mass spectrometry method for the determination of dexamethasone disodium phosphate and dexamethasone in aqueous humor of patients with uveitis. Journal of Pharmaceutical and Biomedical Analysis 142, pages 343-347.
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Phennapha Saokham & Thorsteinn Loftsson. (2017) γ-Cyclodextrin. International Journal of Pharmaceutics 516:1-2, pages 278-292.
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Chutimon Muankaew, Phatsawee Jansook, Hákon Hrafn Sigurđsson & Thorsteinn Loftsson. (2016) Cyclodextrin-based telmisartan ophthalmic suspension: Formulation development for water-insoluble drugs. International Journal of Pharmaceutics 507:1-2, pages 21-31.
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