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Research Articles

Targeted hepatocellular carcinoma therapy: transferrin modified, self-assembled polymeric nanomedicine for co-delivery of cisplatin and doxorubicin

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Pages 1590-1599 | Received 25 Aug 2015, Accepted 13 Feb 2016, Published online: 17 Mar 2016

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Yu Chen, Fukuan Du, Liyao Tang, Jinrun Xu, Yueshui Zhao, Xu Wu, Mingxing Li, Jing Shen, Qinglian Wen, Chi Hin Cho & Zhangang Xiao. (2022) Carboranes as unique pharmacophores in antitumor medicinal chemistry. Molecular Therapy - Oncolytics 24, pages 400-416.
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Yang Guang. (2022) Ligand-modified Nanomaterials for Specific Targeting of Hepatocellular Carcinoma. Journal of Modern Nanotechnology 2:1.
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Mohamed Fawzi Kabil, Maha Nasr & Ibrahim M. El-Sherbiny. (2021) Conventional and hybrid nanoparticulate systems for the treatment of hepatocellular carcinoma: An updated review. European Journal of Pharmaceutics and Biopharmaceutics 167, pages 9-37.
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Laís E. Scheeren, Daniele R. Nogueira-Librelotto, Daniela Mathes, Micheli M. Pillat, Letícia B. Macedo, Montserrat Mitjans, M. Pilar Vinardell & Clarice M.B. Rolim. (2021) Multifunctional PLGA nanoparticles combining transferrin-targetability and pH-stimuli sensitivity enhanced doxorubicin intracellular delivery and in vitro antineoplastic activity in MDR tumor cells. Toxicology in Vitro 75, pages 105192.
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Mohammed Mehadi Hassan Chowdhury, Christiancel Joseph J. Salazar & Md Nurunnabi. (2021) Recent advances in bionanomaterials for liver cancer diagnosis and treatment. Biomaterials Science 9:14, pages 4821-4842.
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Abdulsalam Alhalmi, Sarwar Beg, Kanchan Kohli, Md. Waris & Tanuja Singh. (2021) Nanotechnology Based Approach for Hepatocellular Carcinoma Targeting. Current Drug Targets 22:7, pages 779-792.
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Theeraphong Pho-iam, Primana Punnakitikashem, Chayapol Somboonyosdech, Sirinapa Sripinitchai, Patarabutr Masaratana, Vorapan Sirivatanauksorn, Yongyut Sirivatanauksorn, Chamaiphorn Wongwan, Kytai T. Nguyen & Chatchawan Srisawat. (2021) PLGA nanoparticles containing α-fetoprotein siRNA induce apoptosis and enhance the cytotoxic effects of doxorubicin in human liver cancer cell line. Biochemical and Biophysical Research Communications 553, pages 191-197.
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Jian Zhang, Xiuxiu Wang, Liang Cheng, Jiandong Yuan & Zhiyuan Zhong. (2021) SP94 peptide mediating highly specific and efficacious delivery of polymersomal doxorubicin hydrochloride to hepatocellular carcinoma in vivo. Colloids and Surfaces B: Biointerfaces 197, pages 111399.
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Mahmoud A. Younis, Ikramy A. Khalil & Hideyoshi Harashima. (2020) Gene Therapy for Hepatocellular Carcinoma: Highlighting the Journey from Theory to Clinical Applications. Advanced Therapeutics 3:11, pages 2000087.
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Seyedeh Sara Esnaashari, Samad Muhammadnejad, Saeid Amanpour & Amir Amani. (2020) A Combinational Approach Towards Treatment of Breast Cancer: an Analysis of Noscapine-Loaded Polymeric Nanoparticles and Doxorubicin. AAPS PharmSciTech 21:5.
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Danuta Kuzajewska, Agata Wszołek, Wojciech Żwierełło, Lucyna Kirczuk & Agnieszka Maruszewska. (2020) Magnetotactic Bacteria and Magnetosomes as Smart Drug Delivery Systems: A New Weapon on the Battlefield with Cancer?. Biology 9:5, pages 102.
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Xiaoqin Chi, Kun Liu, Xiangjie Luo, Zhenyu Yin, Hongyu Lin & Jinhao Gao. (2020) Recent advances of nanomedicines for liver cancer therapy. Journal of Materials Chemistry B 8:17, pages 3747-3771.
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Laís E. Scheeren, Daniele R. Nogueira-Librelotto, Letícia B. Macedo, Josiele M. de Vargas, Montserrat Mitjans, M. Pilar Vinardell & Clarice M. B. Rolim. (2020) Transferrin-conjugated doxorubicin-loaded PLGA nanoparticles with pH-responsive behavior: a synergistic approach for cancer therapy. Journal of Nanoparticle Research 22:3.
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Lorena Baboci, Sara Capolla, Federica Di Cintio, Federico Colombo, Prisca Mauro, Michele Dal Bo, Monica Argenziano, Roberta Cavalli, Giuseppe Toffoli & Paolo Macor. (2020) The Dual Role of the Liver in Nanomedicine as an Actor in the Elimination of Nanostructures or a Therapeutic Target. Journal of Oncology 2020, pages 1-15.
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Zhe Ma, Bing Zhang, Yuqi Fan, Meng Wang, Dereje Kebebe, Jiawei Li & Zhidong Liu. (2019) Traditional Chinese medicine combined with hepatic targeted drug delivery systems: A new strategy for the treatment of liver diseases. Biomedicine & Pharmacotherapy 117, pages 109128.
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Likun Hu, Ting Zhang, Dong Liu, Guiwen Guan, Jian Huang, Peter Proksch, Xiangmei Chen & Wenhan Lin. (2019) Notoamide-type alkaloid induced apoptosis and autophagy via a P38/JNK signaling pathway in hepatocellular carcinoma cells . RSC Advances 9:34, pages 19855-19868.
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Mariana Magalhães, Ana Figueiras & Francisco Veiga. 2018. Design and Development of New Nanocarriers. Design and Development of New Nanocarriers 257 291 .
Cristian Turato, Anna Balasso, Vinicio Carloni, Claudio Tiribelli, Francesca Mastrotto, Antonio Mazzocca & Patrizia Pontisso. (2017) New molecular targets for functionalized nanosized drug delivery systems in personalized therapy for hepatocellular carcinoma. Journal of Controlled Release 268, pages 184-197.
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Rinku Dutta & Ram I. Mahato. (2017) Recent advances in hepatocellular carcinoma therapy. Pharmacology & Therapeutics 173, pages 106-117.
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Nourhan K. Mohamed, Mostafa A. Hamad, Mohamed Z.E. Hafez, Karen L. Wooley & Mahmoud Elsabahy. (2017) Nanomedicine in management of hepatocellular carcinoma: Challenges and opportunities. International Journal of Cancer 140:7, pages 1475-1484.
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Baomin Zhu, Huanying Zhang & Lianling Yu. (2017) Novel transferrin modified and doxorubicin loaded Pluronic 85/lipid-polymeric nanoparticles for the treatment of leukemia: In vitro and in vivo therapeutic effect evaluation. Biomedicine & Pharmacotherapy 86, pages 547-554.
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Dazhong Chen, Fangyuan Xie, Duxin Sun, Chuan Yin, Jie Gao & Yanqiang Zhong. (2017) Nanomedicine-Mediated Combination Drug Therapy in Tumor. Open Pharmaceutical Sciences Journal 4:1, pages 1-10.
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Ju Yeon Choi, Raj Kumar Thapa, Chul Soon Yong & Jong Oh Kim. (2016) Nanoparticle-based combination drug delivery systems for synergistic cancer treatment. Journal of Pharmaceutical Investigation 46:4, pages 325-339.
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