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Research Article

Evaluation of Ethylcellulose as a Matrix for Prolonged Release Formulations. II. Sparingly Water-Soluble Drugs: Ibuprofen and Indomethacin

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Pages 2495-2518 | Published online: 20 Oct 2008

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Umesh Nandkumar Khatavkar, Shamkant Laxman Shimpi, K Jayaram Kumar & Kishor Dattatraya Deo. (2013) Development and in vivo evaluation of novel monolithic controlled release compositions of galantamine hydrobromide as against reservoir technology. Pharmaceutical Development and Technology 18:5, pages 1148-1158.
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Mukesh Gohel & Stavan Arunkumar Nagori. (2009) Fabrication and evaluation of captopril modified-release oral formulation. Pharmaceutical Development and Technology 14:6, pages 679-686.
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Carla M. Lopes, José Manuel Sousa Lobo, Paulo Costa & João F. Pinto. (2006) Directly Compressed Mini Matrix Tablets Containing Ibuprofen: Preparation and Evaluation of Sustained Release. Drug Development and Industrial Pharmacy 32:1, pages 95-106.
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George Shlieout & Gerhard Zessin. (1996) Investigation of Ethylcellulose as a Matrix Former and a New Method to Regard and Evaluate the Compaction Data. Drug Development and Industrial Pharmacy 22:4, pages 313-319.
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Sathyanarayana M. Upadrashta, Pruthvipathy R. Katikaneni, Gregory A. Hileman & Prakash R. Keshary. (1993) Direct Compression Controlled Release Tablets Using Ethylcellulose Matrices. Drug Development and Industrial Pharmacy 19:4, pages 449-460.
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K. Tousif Ayyub, Kailas Moravkar, Mohammed Maniruzzaman & Purnima Amin. (2019) Effect of melt extrudability and melt binding efficiency of polyvinyl caprolactam polyvinyl acetate polyethylene glycol graft copolymer (Soluplus®) on release pattern of hydrophilic and high dose drugs. Materials Science and Engineering: C 99, pages 563-574.
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Fred Higton. 2015. Ibuprofen. Ibuprofen 51 80 .
Shuxin Wan, Yingqian Sun, Xiuxiang Qi & Fengping Tan. (2011) Improved Bioavailability of Poorly Water-Soluble Drug Curcumin in Cellulose Acetate Solid Dispersion. AAPS PharmSciTech 13:1, pages 159-166.
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U. Brohede, S. Valizadeh, M. Strømme & G. Frenning. (2007) Percolative drug diffusion from cylindrical matrix systems with unsealed boundaries. Journal of Pharmaceutical Sciences 96:11, pages 3087-3099.
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J. Desai, K. Alexander & A. Riga. (2006) Characterization of polymeric dispersions of dimenhydrinate in ethyl cellulose for controlled release. International Journal of Pharmaceutics 308:1-2, pages 115-123.
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Atsuko FukuiRyuta FujiiYorinobu Yonezawa & Hisakazu Sunada. (2004) Analysis of the Release Process of Phenylpropanolamine Hydrochloride from Ethylcellulose Matrix Granules II. Effects of the Binder Solution on the Release Process. Chemical and Pharmaceutical Bulletin 52:3, pages 298-302.
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Michael M. Crowley, Britta Schroeder, Anke Fredersdorf, Sakae Obara, Mark Talarico, Shawn Kucera & James W. McGinity. (2004) Physicochemical properties and mechanism of drug release from ethyl cellulose matrix tablets prepared by direct compression and hot-melt extrusion. International Journal of Pharmaceutics 269:2, pages 509-522.
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Y. Ikeda, S. Motoune, M. Ono, H. Arima, F. Hirayama & K. Uekama. (2004) Potential use of 2-hydroxypropyl-?-cyclodextrin as a release modifier of a water-soluble drug, metoprolol tartrate, from ethylcellulose tablets. Journal of Drug Delivery Science and Technology 14:1, pages 69-76.
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Anjali M. Agrawal, Steven H. Neau & Peter L. Bonate. (2015) Wet granulation fine particle ethylcellulose tablets: Effect of production variables and mathematical modeling of drug release. AAPS PharmSci 5:2, pages 48-60.
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Atsuko FukuiRyuta FujiiYorinobu Yonezawa & Hisakazu Sunada. (2002) Analysis of the Release Process of Phenylpropanolamine Hydrochloride from Ethylcellulose Matrix Granules.. Chemical and Pharmaceutical Bulletin 50:11, pages 1439-1442.
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Majeti N. V. Ravi Kumar, Neeraj Kumar, A. J. Domb & Meenakshi Arora. 2002. Filled Elastomers Drug Delivery Systems. Filled Elastomers Drug Delivery Systems 45 117 .
Steven H Neau, Matthew A Howard, John S Claudius & Danny R Howard. (1999) The effect of the aqueous solubility of xanthine derivatives on the release mechanism from ethylcellulose matrix tablets. International Journal of Pharmaceutics 179:1, pages 97-105.
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Mohammad A. Dabbagh, James L. Ford, Michael H. Rubinstein & John E. Hogan. (1996) Effects of polymer particle size, compaction pressure and hydrophilic polymers on drug release from matrices containing ethylcellulose. International Journal of Pharmaceutics 140:1, pages 85-95.
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Sung Bum La, Teruo Okano & Kazunori Kataoka. (1996) Preparation and Characterization of the Micelle-Forming Polymeric Drug Indomethacin-lncorporated Polyfethylene oxide)-Poly(β-benzyl L-aspartate) Block Copolymer Micelles. Journal of Pharmaceutical Sciences 85:1, pages 85-90.
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P. Albin, A. Markus, Z. Pelah & Z. Ben-Zvi. (1994) Slow-release indomethacin formulations based on polysaccharides: evaluation in vitro and in vivo in dogs. Journal of Controlled Release 29:1-2, pages 25-39.
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Severian Dumitriu & Maria Dumitriu. (1991) Bioactive polymers 66. Theophylline retardation in xanthan-based hydrogels. Biomaterials 12:9, pages 821-826.
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Michelle R. Jenquin, Stephen M. Liebowitz, Rafael E. Sarabia & James W. McGinity. (1990) Physical and Chemical Factors Influencing the Release of Drugs from Acrylic Resin Films. Journal of Pharmaceutical Sciences 79:9, pages 811-816.
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