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Research Article

Evaluation of Ethylcellulose as A Matrix for Prolonged Release Formulations. I. Water Soluble Drugs: Acetaminophen and Theophylline

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Pages 1345-1369 | Published online: 20 Oct 2008

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Read on this site (16)

Hailong Li, Xin-Sheng Chai, Huaiyu Zhan, Mengru Liu & Shiyu Fu. (2012) A Novel Method for Determination of Ethoxyl Content in Ethyl Cellulose by Headspace Gas Chromatography. Analytical Letters 45:9, pages 1028-1035.
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Sabahuddin Siddique, Anirbandeep Bose & Jasmina Khanam. (2011) Modulation of drug (metoprolol succinate) release by inclusion of hydrophobic polymer in hydrophilic matrix. Drug Development and Industrial Pharmacy 37:9, pages 1016-1025.
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Na Chi, Ju Hong Guo, Yu Zhang, Wei Zhang & Xing Tang. (2010) An oral controlled release system for amroxol hydrochloride containing a wax and a water insoluble polymer. Pharmaceutical Development and Technology 15:1, pages 97-104.
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Mukesh Gohel & Stavan Arunkumar Nagori. (2009) Fabrication and evaluation of captopril modified-release oral formulation. Pharmaceutical Development and Technology 14:6, pages 679-686.
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Gul Majid Khan & Victor M. Meidan. (2007) Drug Release Kinetics from Tablet Matrices Based Upon Ethylcellulose Ether-Derivatives: A Comparison Between Different Formulations. Drug Development and Industrial Pharmacy 33:6, pages 627-639.
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Poj Kulvanich, Phuriwat Leesawat & Vipaluk Patomchaiviwat. (2002) Release Characteristics of the Matrices Prepared from Co-spray-Dried Powders of Theophylline and Ethylcellulose. Drug Development and Industrial Pharmacy 28:6, pages 727-739.
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George Shlieout & Gerhard Zessin. (1996) Investigation of Ethylcellulose as a Matrix Former and a New Method to Regard and Evaluate the Compaction Data. Drug Development and Industrial Pharmacy 22:4, pages 313-319.
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P. Dangprasirt & G. C. Ritthidej. (1995) Development of Diclofenac Sodium Controlled Release Solid Dispersions by Spray Drying Using Optimization Strategy I. Powder Formulation. Drug Development and Industrial Pharmacy 21:20, pages 2323-2337.
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J. I. Hernandez, E. S. Ghal, A. Malave & A. Marti. (1994) Controlled-Release Matrix of Acetaminophen-Ethylcellulose Solid Dispersion. Drug Development and Industrial Pharmacy 20:7, pages 1253-1265.
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A. G. Eshra, K. A. Elkhodairy, S. A. M. Mortada & A. H. Nada. (1994) Preparation and evaluation of slow-release pan-coated indomethacin granules. Journal of Microencapsulation 11:3, pages 271-278.
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Sathyanarayana M. Upadrashta, Pruthvipathy R. Katikaneni, Gregory A. Hileman & Prakash R. Keshary. (1993) Direct Compression Controlled Release Tablets Using Ethylcellulose Matrices. Drug Development and Industrial Pharmacy 19:4, pages 449-460.
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Claude Brossard, Voahirana Ratsimbazafy & Daniel Lefort des Ylouses. (1991) Modelling of Theophylline Compound Release from Hard Gelatin Capsules Containing Gelucire Matrix Granules. Drug Development and Industrial Pharmacy 17:10, pages 1267-1277.
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Omaimah M.N. Al Gohary, Seham S. Abd El Hady & Nabila A. Daabis. (1991) Sustained Release Matrix of Mebeverine Hydrochloride Using Polyacrylate Resin “Eudragit Retard” Kinetic of Drug Release and Evaluation of a Kinetic Model. Drug Development and Industrial Pharmacy 17:15, pages 2055-2065.
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M. Georgarakis, A. Panagopoulou, P. Hatzipantou, Th. Iliopoulos, M. Kondylis & D. Grekas. (1990) Development of a New Controlled Release Theophylline Tablet: In Vitro and in Vivo Studies. Drug Development and Industrial Pharmacy 16:2, pages 315-329.
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Yamin Zhao, Lujun Zhang, Xiaoxue Zhai, Qian Liu, Lebing Sun, Mengshi Liu, Lili An, Liang Xian, Ping Zhang & Lihua Chen. (2021) Study on Adsorption Performance of Benzoic Acid in Cyclocarya paliurus Extract by Ethyl Cellulose Microspheres. Chemistry 3:4, pages 1113-1125.
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R. Djerafi, Y. Masmoudi, C. Crampon, A. Meniai & E. Badens. (2015) Supercritical anti-solvent precipitation of ethyl cellulose. The Journal of Supercritical Fluids 105, pages 92-98.
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Jong-Suep Baek, Won-Gi Yeon, Cho-A Lee, Sung-Joo Hwang, Jeong-Sook Park, Dong-Chool Kim & Cheong-Weon Cho. (2014) Preparation and characterization of mucoadhesive enteric-coating ginsenoside-loaded microparticles. Archives of Pharmacal Research 38:5, pages 761-768.
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Ravindra Tiwari, Sunil Kumar Agarwal, R. S. R. Murthy & Shweta Tiwari. (2014) Formulation and Evaluation of Sustained Release Extrudes Prepared via Novel Hot Melt Extrusion Technique. Journal of Pharmaceutical Innovation 9:3, pages 246-258.
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Richer Chen, Hirokazu Okamoto & Kazumi Danjo. (2008) Preparation of Functional Composite Particles of Salbutamol Sulfate Using a 4-Fluid Nozzle Spray-Drying Technique. CHEMICAL & PHARMACEUTICAL BULLETIN 56:3, pages 254-259.
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U. Brohede, S. Valizadeh, M. Strømme & G. Frenning. (2007) Percolative drug diffusion from cylindrical matrix systems with unsealed boundaries. Journal of Pharmaceutical Sciences 96:11, pages 3087-3099.
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Mani Prabaharan & João F. Mano. (2006) Stimuli-Responsive Hydrogels Based on Polysaccharides Incorporated with Thermo-Responsive Polymers as Novel Biomaterials. Macromolecular Bioscience 6:12, pages 991-1008.
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Riikka Mäki, Eero Suihko, Ossi Korhonen, Heli Pitkänen, Riku Niemi, Marko Lehtonen & Jarkko Ketolainen. (2006) Controlled release of saccharides from matrix tablets. European Journal of Pharmaceutics and Biopharmaceutics 62:2, pages 163-170.
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Richer Chen, Hirokazu Okamoto & Kazumi Danjo. (2006) Particle Design Using a 4-Fluid-Nozzle Spray-Drying Technique for Sustained Release of Acetaminophen. CHEMICAL & PHARMACEUTICAL BULLETIN 54:7, pages 948-953.
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Richer Chen, Hirokazu Takahashi, Hirokazu Okamoto & Kazumi Danjo. (2006) Particle Design of Three-Component System for Sustained Release Using a 4-Fluid Nozzle Spray-Drying Technique. CHEMICAL & PHARMACEUTICAL BULLETIN 54:11, pages 1486-1490.
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Hirokazu Takahashi, Richer Chen, Hirokazu Okamoto & Kazumi Danjo. (2005) Acetaminophen Particle Design Using Chitosan and a Spray-Drying Technique. CHEMICAL & PHARMACEUTICAL BULLETIN 53:1, pages 37-41.
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Michael M. Crowley, Britta Schroeder, Anke Fredersdorf, Sakae Obara, Mark Talarico, Shawn Kucera & James W. McGinity. (2004) Physicochemical properties and mechanism of drug release from ethyl cellulose matrix tablets prepared by direct compression and hot-melt extrusion. International Journal of Pharmaceutics 269:2, pages 509-522.
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Anjali M. Agrawal, Steven H. Neau & Peter L. Bonate. (2015) Wet granulation fine particle ethylcellulose tablets: Effect of production variables and mathematical modeling of drug release. AAPS PharmSci 5:2, pages 48-60.
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Majeti N. V. Ravi Kumar, Neeraj Kumar, A. J. Domb & Meenakshi Arora. 2002. Filled Elastomers Drug Delivery Systems. Filled Elastomers Drug Delivery Systems 45 117 .
Gul Majid Khan .Jia-Bi Zhu .. (2001) Evaluation of Ethocel® Premium Ethylcellulose Ether Derivatives with Different Molecular Weights as Controlled-release Matrix Forming Functional Polymers for Ibuprofen. Journal of Medical Sciences 1:6, pages 361-367.
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Gul Majid Khan .. (2001) Controlled Release Oral Dosage Forms: Some Recent Advances in Matrix Type Drug Delivery Systems. Journal of Medical Sciences(Faisalabad) 1:5, pages 350-354.
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Steven H Neau, Matthew A Howard, John S Claudius & Danny R Howard. (1999) The effect of the aqueous solubility of xanthine derivatives on the release mechanism from ethylcellulose matrix tablets. International Journal of Pharmaceutics 179:1, pages 97-105.
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Mansoor A. Khan & Indra K. Reddy. 1998. Calcium Phosphates in Biological and Industrial Systems. Calcium Phosphates in Biological and Industrial Systems 303 323 .
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Georgeta Mocanu, A. Airinei & A. Carpov. (1996) Macromolecular drug conjugates. V. Theophylline-dextran. Journal of Controlled Release 40:1-2, pages 1-9.
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Pruthvipathy R. Katikaneni, Sathyanarayana M. Upadrashta, Steven H. Neau & Amit K. Mitra. (1995) Ethylcellulose matrix controlled release tablets of a water-soluble drug. International Journal of Pharmaceutics 123:1, pages 119-125.
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Sathyanarayana M. Upadrashta, Pruthvipathy R. Katikaneni, Gregory A. Hileman, Steven H. Neau & Colin E. Rowlings. (1994) Compressibility and compactibility properties of ethylcellulose. International Journal of Pharmaceutics 112:2, pages 173-179.
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Jen‐Chin Wu, Wen‐Jiunn Jean & Hui Chen. (2013) Preparation and Release Behavior of Ethylcellulose Microcapsules Containing Theophylline Dispersed in Cellulose Triacetate Matrices. Journal of the Chinese Chemical Society 40:1, pages 23-28.
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Shigeru Aoki, Takayuki Ohwaki, Keizo Uesugi, Kimio Tatsuishi, Hiroshi Ozawa & Masanori Kayano. (1992) Preparation of a novel type of controlled-release carrier and evaluation of drug release from the matrix tablet and its physical properties. International Journal of Pharmaceutics 85:1-3, pages 29-38.
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