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Research Article

Coated Drug Cores in Multiple Unit Preparations Influence of Particle Size

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Pages 2285-2297 | Published online: 20 Oct 2008

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Jessica Bile, Marie-Alexandrine Bolzinger, Jean-Pierre Valour, Hatem Fessi & Yves Chevalier. (2016) Antimicrobial films containing microparticles for the enhancement of long-term sustained release. Drug Development and Industrial Pharmacy 42:5, pages 818-824.
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Matevž Luštrik, Rok Dreu, Rok Šibanc & Stanko Srčič. (2012) Comparative study of the uniformity of coating thickness of pellets coated with a conventional Wurster chamber and a swirl generator-equipped Wurster chamber. Pharmaceutical Development and Technology 17:3, pages 268-276.
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Chien Nguyen, J. Mark Christensen & James W. Ayres. (2012) Verapamil sustained release: New formulation and convolution. Pharmaceutical Development and Technology 17:2, pages 148-157.
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Chien Nguyen, J. Mark Christensen & James W. Ayres. (2012) Novel mesalamine-loaded beads in tablets for delayed release of drug to the colon. Pharmaceutical Development and Technology 17:1, pages 73-83.
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Grant Heinicke & Joseph B. Schwartz. (2007) Ammonio Polymethacrylate-Coated Diltiazem: Drug Release from Single Pellets, Media Dependence, and Swelling Behavior. Pharmaceutical Development and Technology 12:3, pages 285-296.
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Yuh-Tyng Huang, Tong-Rong Tsai, Chun-Jen Cheng, Thau-Ming Cham, Tsun-Fwu Lai & Wen-Ho Chuo. (2007) Formulation Design of a Highly Hygroscopic Drug (Pyridostigmine Bromide) for its Hygroscopic Character Improvement and Investigation of In Vitro/In Vivo Dissolution Properties. Drug Development and Industrial Pharmacy 33:4, pages 403-416.
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Robert A. Miller, Edwin M. K. Leung & Randal J. Oates. (1999) The Compression of Spheres Coated with an Aqueous Ethylcellulose Dispersion. Drug Development and Industrial Pharmacy 25:4, pages 503-511.
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Kaisri Umprayn, Padungkwan Chitropas & Sukavat Amarekajorn. (1999) Development of Terbutaline Sulfate Sustained-Release Coated Pellets. Drug Development and Industrial Pharmacy 25:4, pages 477-491.
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P. B. Deasy. (1994) Evaluation of Drug-Containing Microcapsules. Journal of Microencapsulation 11:5, pages 487-505.
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Articles from other publishers (31)

Mohammad Foroughi-Dahr, Rahmat Sotudeh-Gharebagh & Navid Mostoufi. (2019) Effect of operation conditions on coating of pharmaceutical pellets with a film of HPMC/PEG in a Wurster coater. Powder Technology 354, pages 804-814.
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Bifeng Wang & Wolfgang Friess. (2017) Formation of mannitol core microparticles for sustained release with lipid coating in a mini fluid bed system. European Journal of Pharmaceutics and Biopharmaceutics 120, pages 126-132.
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Ali R. Rajabi-Siahboomi, Raxit Y. Mehta, Vaibhav Ambudkar, Viena Dias & Sandip Tiwari. 2017. Multiparticulate Drug Delivery. Multiparticulate Drug Delivery 267 299 .
Felipe L. Lopez, Alexandra Bowles, Mine Orlu Gul, David Clapham, Terry B. Ernest & Catherine Tuleu. (2016) Effect of formulation variables on oral grittiness and preferences of multiparticulate formulations in adult volunteers. European Journal of Pharmaceutical Sciences 92, pages 156-162.
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Anwesha Chaudhury, Maitraye Sen, Dana Barrasso & Rohit Ramachandran. 2016. Process Simulation and Data Modeling in Solid Oral Drug Development and Manufacture. Process Simulation and Data Modeling in Solid Oral Drug Development and Manufacture 43 83 .
Jianfeng Li, Ben Freireich, Carl Wassgren & James D. Litster. (2012) A general compartment-based population balance model for particle coating and layered granulation. AIChE Journal 58:5, pages 1397-1408.
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Abraham B. Bashaiwoldu, Fridrun Podczeck & J. Michael Newton. (2011) Compaction of and drug release from coated pellets of different mechanical properties. Advanced Powder Technology 22:3, pages 340-353.
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Shayne Cox GadAnette Larsson, Susanna Abrahmsén-Alami & Anne Juppo. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia.
Abraham B Bashaiwoldu, Fridrun Podczeck & J Michael Newton. (2006) Factorial designed experiment to study the effects of excipients on the mechanical properties of pellets. Journal of Pharmacy and Pharmacology 58:10, pages 1305-1309.
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Takayuki Yoshida, Hiroaki Tasaki, Atsushi Maeda, Masataka Katsuma, Kazuhiro Sako & Takahiro Uchida. (2008) Optimization of Salting-Out Taste-Masking System for Micro-Beads Containing Drugs with High Solubility. CHEMICAL & PHARMACEUTICAL BULLETIN 56:11, pages 1579-1584.
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Elaine S K Tang, L W Chan & Paul W S Heng. (2005) Coating of Multiparticulates for Sustained Release. American Journal of Drug Delivery 3:1, pages 17-28.
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Abraham B. Bashaiwoldu, F. Podczeck & J.M. Newton. (2004) Application of Dynamic Mechanical Analysis (DMA) to the determination of the mechanical properties of coated pellets. International Journal of Pharmaceutics 274:1-2, pages 53-63.
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I. Tomuta & S.E. Leucuta. (2004) Use of experimental design for identifying the most important formulation and technological variables in pelletization by powder layering. Journal of Drug Delivery Science and Technology 14:3, pages 215-221.
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Norihito ShimonoMasumi UedaYasuhiko Nakamura. (2002) Design of Controlled Release System with Multi-layers of Powder.. Chemical and Pharmaceutical Bulletin 50:9, pages 1169-1175.
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Claudio Nastruzzi, Rita Cortesi, Elisabetta Esposito, Alberto Genovesi, Alessandro Spadoni, Carlo Vecchio & Enea Menegatti. (2000) Influence of formulation and process parameters on pellet production by powder layering technique. AAPS PharmSciTech 1:2, pages 14-25.
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Martin Andersson, Staffan Folestad, Johan Gottfries, Mats O. Johansson, Mats Josefson & Karl-Gustav Wahlund. (2000) Quantitative Analysis of Film Coating in a Fluidized Bed Process by In-Line NIR Spectrometry and Multivariate Batch Calibration. Analytical Chemistry 72:9, pages 2099-2108.
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K. Sudsakorn & R. Turton. (2000) Nonuniformity of particle coating on a size distribution of particles in a fluidized bed coater. Powder Technology 110:1-2, pages 37-43.
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Martin Andersson, Björn Holmquist, Jörgen Lindquist, Olle Nilsson & Karl-Gustav Wahlund. (2000) Analysis of film coating thickness and surface area of pharmaceutical pellets using fluorescence microscopy and image analysis. Journal of Pharmaceutical and Biomedical Analysis 22:2, pages 325-339.
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Karl G. Wagner, Markus Krumme & Peter C. Schmidt. (1999) Investigation of the pellet-distribution in single tablets via image analysis. European Journal of Pharmaceutics and Biopharmaceutics 47:1, pages 79-85.
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Claudio Alexander Lorck, Petra Christine Grunenberg, Herbert Jünger & Arním Laicher. (1997) Influence of process parameters on sustained-release theophylline pellets coated with aqueous polymer dispersions and organic solvent-based polymer solutions. European Journal of Pharmaceutics and Biopharmaceutics 43:2, pages 149-157.
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Roland Bodmeier. (1997) Tableting of coated pellets. European Journal of Pharmaceutics and Biopharmaceutics 43:1, pages 1-8.
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Thomas E. Beckert, Klaus Lehmann & Peter C. Schmidt. (1996) Compression of enteric-coated pellets to disintegrating tablets. International Journal of Pharmaceutics 143:1, pages 13-23.
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Gert Ragnarsson, Anders Sandberg, Mats O. Johansson, Bengt Lindstedt & John Sjögren. (1992) In vitro release characteristics of a membrane-coated pellet formulation — influence of drug solubility and particle size. International Journal of Pharmaceutics 79:1-3, pages 223-232.
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R. Wesdyk, Y.M. Joshi, N.B. Jain, K. Morris & A. Newman. (1990) The effect of size and mass on the film thickness of beads coated in fluidized bed equipment. International Journal of Pharmaceutics 65:1-2, pages 69-76.
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