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S. A. M. Binhowimal, L. Hanzic & J. C. M. Ho. (2017) Filler to improve concurrent flowability and segregation performance of concrete. Australian Journal of Structural Engineering 18:2, pages 73-85.
Read now
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Julian Quodbach & Peter Kleinebudde. (2016) A critical review on tablet disintegration. Pharmaceutical Development and Technology 21:6, pages 763-774.
Read now
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Dali Shukla, Subhashis Chakraborty, Sanjay Singh & Brahmeshwar Mishra. (2011) Lipid-based oral multiparticulate formulations – advantages, technological advances and industrial applications. Expert Opinion on Drug Delivery 8:2, pages 207-224.
Read now
Read now
Anna Cecilia Jørgensen & Anette Seo Torstenson. (2008) Humid Storage Conditions Increase the Dissolution Rate of Diazepam from Solid Dispersions Prepared by Melt Agglomeration. Pharmaceutical Development and Technology 13:3, pages 187-195.
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Wai See Cheong, Paul Wan Sia Heng & Tin Wui Wong. (2007) Impact of a Non-meltable Additive on Melt Agglomeration with a Hydrophobic Meltable Binder in High-Shear Mixer. Pharmaceutical Development and Technology 12:4, pages 371-380.
Read now
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L. Gu, C. V. Liew & P. W.S. Heng. (2004) Wet Spheronization by Rotary Processing—A Multistage Single‐Pot Process for Producing Spheroids. Drug Development and Industrial Pharmacy 30:2, pages 111-123.
Read now
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Yu-E Zhang, Ruy Tchao & Joseph B. Schwartz. (2001) Effect of Processing Methods and Heat Treatment on the Formation of Wax Matrix Tablets for Sustained Drug Release. Pharmaceutical Development and Technology 6:2, pages 131-144.
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Jiasheng Tu, Linbo Wang, Jing Yang, He Fei & Xuemin Li. (2001) Formulation and Pharmacokinetic Studies of Acyclovir Controlled-Release Capsules. Drug Development and Industrial Pharmacy 27:7, pages 687-692.
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T. W. Wong, L. S. C. Wan & P. W. S. Heng. (1999) Effects of Physical Properties of PEG 6000 on Pellets Produced by Melt Pelletization. Pharmaceutical Development and Technology 4:3, pages 449-456.
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B. Evrard, K. Amighi, D. Beten, L. Delattre & A. J. Moës. (1999) Influence of Melting and Rheological Properties of Fatty Binders on the Melt Granulation Process in a High-Shear Mixer. Drug Development and Industrial Pharmacy 25:11, pages 1177-1184.
Read now
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Alan Royce, Jiwaji Suryawanshi, Udayan Shah & Krishna Vishnupad. (1996) Alternative Granulation Technique: Melt Granulation. Drug Development and Industrial Pharmacy 22:9-10, pages 917-924.
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L. Juul Thomsen, T. Schaefer & H. G. Kristensen. (1994) Prolonged Release Matrix Pellets Prepared by Melt Pelletization II. Hydrophobic Substances as Meltable Binders. Drug Development and Industrial Pharmacy 20:7, pages 1179-1197.
Read now
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Kenji Ukita & Toshio Murakami. (1994) Preparation of Essential Oils Loaded Granule by Melt Granulation. Drug Development and Industrial Pharmacy 20:6, pages 981-992.
Read now
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L. Juul Thomsen, T. Schæfer, J. M. Sonnergaard & H. G. Kristensen. (1993) Prolonged release Matrix Pellets Prepared by Melt Pelletization I. Process Variables. Drug Development and Industrial Pharmacy 19:15, pages 1867-1887.
Read now
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D. Vojnovic, P. Selenati, F. Rubessa, M. Moneghini & A. Zanchetta. (1992) Wet Granulation in a Small Scale High Shear Mixer. Drug Development and Industrial Pharmacy 18:9, pages 961-972.
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Articles from other publishers (75)
William Kennedy Walls, James A. Thompson & Stephen G.R. Brown. (2022) Towards a unified theory of wet agglomeration. Powder Technology 407, pages 117519.
Crossref
Crossref
Victoria Nahum & Abraham J. Domb. (2022) Solid lipid microspheres decorated nanoparticles as drug carriers. International Journal of Pharmaceutics 621, pages 121797.
Crossref
Crossref
Tongzhou Liu, Navpreet Kaur, Beibei Chen, Brian Phillips, Shao-Yu Chang, Fengyuan Yang, Vivian Bi, Thomas Durig & Feng Zhang. (2022) Physicochemical changes and chemical degradation of gliclazide during twin-screw melt granulation. International Journal of Pharmaceutics 619, pages 121702.
Crossref
Crossref
Aurélien Sivert, Randy Wald, Chris Craig & Hassan Benameur. 2022. Oral Drug Delivery for Modified Release Formulations. Oral Drug Delivery for Modified Release Formulations
235
252
.
Kristina E. Steffens & Karl G. Wagner. (2021) Immediate-Release Formulations Produced via Twin-Screw Melt Granulation: Systematic Evaluation of the Addition of Disintegrants. AAPS PharmSciTech 22:5.
Crossref
Crossref
Krunoslav Žižek, Martin Gojun & Ivana Grčić. (2021) Simulating the wet granulation of TiO2 photocatalyst in fluidized bed: Population balance modelling and prediction of coalescence rate. Powder Technology 379, pages 1-11.
Crossref
Crossref
Tongzhou Liu, Nada Kittikunakorn, Yi Zhang & Feng Zhang. (2021) Mechanisms of twin screw melt granulation. Journal of Drug Delivery Science and Technology 61, pages 102150.
Crossref
Crossref
Tongzhou Liu, Shubhajit Paul, Brian T Beeson, Johnny Alexander, Fengyuan Yang, Vivian Bi, Thomas Durig, Changquan Calvin Sun & Feng Zhang. (2020) Effect of Hydroxypropyl Cellulose Level on Twin-Screw Melt Granulation of Acetaminophen. AAPS PharmSciTech 21:7.
Crossref
Crossref
Jeremiah F. Kelleher, Atif M. Madi, Gareth C. Gilvary, Y. W. Tian, Shu Li, Ammar Almajaan, Zoe S. Loys, David S. Jones, Gavin P. Andrews & Anne Marie Healy. (2019) Metformin Hydrochloride and Sitagliptin Phosphate Fixed-Dose Combination Product Prepared Using Melt Granulation Continuous Processing Technology. AAPS PharmSciTech 21:1.
Crossref
Crossref
Kai Shiino, Takao OshimaRyoichi SonodaShin-ichiro Kimura, Shigeru Itai & Yasunori Iwao. (2019) Controlled-Release Fine Particles Prepared by Melt Adsorption for Orally Disintegrating Tablets. Chemical and Pharmaceutical Bulletin 67:10, pages 1152-1159.
Crossref
Crossref
Jonathan B. Wade. 2019. Handbook of Pharmaceutical Wet Granulation. Handbook of Pharmaceutical Wet Granulation
3
35
.
Xin Feng & Feng Zhang. (2017) Twin-screw extrusion of sustained-release oral dosage forms and medical implants. Drug Delivery and Translational Research 8:6, pages 1694-1713.
Crossref
Crossref
Veronica De Simone, Diego Caccavo, Annalisa Dalmoro, Gaetano Lamberti, Matteo d’Amore & Anna Angela Barba. 2018. Granularity in Materials Science. Granularity in Materials Science.
Mohamed Abbas Ibrahim & Gamal Mohamed Mahrous. (2018) Effect of wet mass on dextromethorphan hydrobromide matrix pellets. Brazilian Journal of Pharmaceutical Sciences 54:4.
Crossref
Crossref
Brendan Alex Kounakoff, Lucija Hanzic & Johnny Ching Ming Ho. (2017) Limestone and silica fume to improve concurrent flowability–segregation limits of concrete. Magazine of Concrete Research 69:23, pages 1189-1202.
Crossref
Crossref
Doaa Ahmed El-Setouhy, Emad B. Basalious & Nevine Shawky Abdelmalak. (2017) Effect of Different Meltable Binders on the Disintegration and Dissolution Behavior of Zolmitriptan Oromucosal Fast Melt Tablets. Journal of Pharmacy and Nutrition Sciences 7:1, pages 13-23.
Crossref
Crossref
Kai Shiino, Yukari Fujinami, Shin-ichiro Kimura, Yasunori Iwao, Shuji Noguchi & Shigeru Itai. (2017) Melt Adsorption as a Manufacturing Method for Fine Particles of Wax Matrices without Any Agglomerates. CHEMICAL & PHARMACEUTICAL BULLETIN Chemical and Pharmaceutical Bulletin 65:8, pages 726-731.
Crossref
Crossref
Amol Batra, Dipen Desai & Abu T.M. Serajuddin. (2017) Investigating the Use of Polymeric Binders in Twin Screw Melt Granulation Process for Improving Compactibility of Drugs. Journal of Pharmaceutical Sciences 106:1, pages 140-150.
Crossref
Crossref
Manogna Adepu, Siddhi Hate, Angelique Bétard, Sarang Oka, Marek Schongut, Maitraye Sen, Yadvaindera Sood, Dorit Wolf, Stefan Wieland, Frantisek Stepanek, Fernando Muzzio, Benjamin Glasser & Rohit Ramachandran. (2016) Quantitative validation and analysis of the regime map approach for the wet granulation of industrially relevant zirconium hydroxide powders. Powder Technology 294, pages 177-184.
Crossref
Crossref
Karin Becker, Sharareh Salar-Behzadi & Andreas Zimmer. (2015) Solvent-Free Melting Techniques for the Preparation of Lipid-Based Solid Oral Formulations. Pharmaceutical Research 32:5, pages 1519-1545.
Crossref
Crossref
C. Eckert, M. Pein & J. Breitkreutz. (2014) Lean production of taste improved lipidic sodium benzoate formulations. European Journal of Pharmaceutics and Biopharmaceutics 88:2, pages 455-461.
Crossref
Crossref
Krunoslav ?i?ek, Marin Hraste & Zoran Gomzi. (2014) High shear granulation of dolomite ? II: Effect of amount of binder liquid on process kinetics. Chemical Engineering Research and Design 92:6, pages 1091-1106.
Crossref
Crossref
Sanni Matero, Frans van Den Berg, Sami Poutiainen, Jukka Rantanen & Jari Pajander. (2013) Towards Better Process Understanding: Chemometrics and Multivariate Measurements in Manufacturing of Solid Dosage Forms. Journal of Pharmaceutical Sciences 102:5, pages 1385-1403.
Crossref
Crossref
U.S Desai, P.D Chaudhari, D.B. Bhavsar & R.P. Chavan. (2013) MELT GRANULATION: AN ALTERNATIVE TO TRADITIONAL GRANULATION TECHNIQUES. INDIAN DRUGS 50:03, pages 5-13.
Crossref
Crossref
Kai Shiino, Yasunori Iwao, Yukari Fujinami & Shigeru Itai. (2012) Preparation and evaluation of granules with pH-dependent release by melt granulation. International Journal of Pharmaceutics 431:1-2, pages 70-77.
Crossref
Crossref
Ivana Mašić, Ilija Ilić, Rok Dreu, Svetlana Ibrić, Jelena Parojčić & Zorica Đurić. (2012) An investigation into the effect of formulation variables and process parameters on characteristics of granules obtained by in situ fluidized hot melt granulation. International Journal of Pharmaceutics 423:2, pages 202-212.
Crossref
Crossref
Pankaj B. Pathare, Nursin Baş, John J. Fitzpatrick, Kevin Cronin & Edmond P. Byrne. (2011) Effect of high shear granulation process parameters on the production of granola cereal aggregates. Biosystems Engineering 110:4, pages 473-481.
Crossref
Crossref
Zhen Guo, Mingxin Ma, Yanru Hao, Tongying Jiang & Siling Wang. (2011) An investigation on the correlation between drug dissolution properties and the growth behaviour of granules in high shear mixer. Journal of Pharmacy and Pharmacology 63:12, pages 1548-1558.
Crossref
Crossref
Dali Shukla, Subhashis Chakraborty, Sanjay Singh & Brahmeshwar Mishra. (2011) Pastillation: A novel technology for development of oral lipid based multiparticulate controlled release formulation. Powder Technology 209:1-3, pages 65-72.
Crossref
Crossref
Shailesh T. Prajapati, Amit N. Patel & Chhagan N. Patel. (2011) Formulation and Evaluation of Controlled-Release Tablet of Zolpidem Tartrate by Melt Granulation Technique. ISRN Pharmaceutics 2011, pages 1-8.
Crossref
Crossref
Saadia A. Tayel, Iman I. Soliman & Dina Louis. (2010) Formulation of Ketotifen Fumarate Fast-Melt Granulation Sublingual Tablet. AAPS PharmSciTech 11:2, pages 679-685.
Crossref
Crossref
J. Canotilho, R. A. E. Castro, M. T. S. Rosado, S. C. C. Nunes, M. S. C. Cruz & J. S. Redinha. (2010) Thermal analysis and crystallization from melts. Journal of Thermal Analysis and Calorimetry 100:2, pages 423-429.
Crossref
Crossref
Nazar M. Ranjha, Hafeezullah Khan & Shahzad Naseem. (2010) Encapsulation and characterization of controlled release flurbiprofen loaded microspheres using beeswax as an encapsulating agent. Journal of Materials Science: Materials in Medicine 21:5, pages 1621-1630.
Crossref
Crossref
B. Daumann, X. Sun, H. Anlauf, S. Gerl & H. Nirschl. (2010) Mixing Agglomeration in a High‐Shear Mixer with a Stirred Mixing Vessel. Chemical Engineering & Technology 33:2, pages 321-326.
Crossref
Crossref
P. Bukovec, V. Kro?elj, S. Turk & F. Vre?er. (2009) Optimization of melt pelletization in a high shear mixer. International Journal of Pharmaceutics 381:2, pages 192-198.
Crossref
Crossref
Rahul Dixit & Shivanand Puthli. (2009) Fluidization technologies: Aerodynamic principles and process engineering. Journal of Pharmaceutical Sciences 98:11, pages 3933-3960.
Crossref
Crossref
James Kowalski, Oskar Kalb, Yatindra M. Joshi & Abu T.M. Serajuddin. (2009) Application of melt granulation technology to enhance stability of a moisture sensitive immediate-release drug product. International Journal of Pharmaceutics 381:1, pages 56-61.
Crossref
Crossref
Wei-Da Tu, Shu-San Hsiau, Andy Ingram & Jonathan Seville. (2008) The effect of powder size on induction behaviour and binder distribution during high shear melt agglomeration of calcium carbonate. Powder Technology 184:3, pages 298-312.
Crossref
Crossref
V. Jannin, J. Musakhanian & D. Marchaud. (2008) Approaches for the development of solid and semi-solid lipid-based formulations. Advanced Drug Delivery Reviews 60:6, pages 734-746.
Crossref
Crossref
Gavin P Andrews. (2007) Advances in solid dosage form manufacturing technology. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 365:1861, pages 2935-2949.
Crossref
Crossref
B.H. Ng, C.C. Kwan, Y.L. Ding, M. Ghadiri & X.F. Fan. (2007) Solids motion of calcium carbonate particles in a high shear mixer granulator: A comparison between dry and wet conditions. Powder Technology 177:1, pages 1-11.
Crossref
Crossref
B.H. Ng, C.C. Kwan, Y.L. Ding, M. Ghadiri & X.F. Fan. (2007) Solids motion in a conical frustum-shaped high shear mixer granulator. Chemical Engineering Science 62:3, pages 756-765.
Crossref
Crossref
Gavin K. Reynolds, Phung K. Le & Amol M. Nilpawar. 2007. Granulation. Granulation
3
19
.
Jamila Hamdani, André J. Moës & Karim Amighi. (2006) Development and in vitro evaluation of a novel floating multiple unit dosage form obtained by melt pelletization. International Journal of Pharmaceutics 322:1-2, pages 96-103.
Crossref
Crossref
S.L. Rough, D.I. Wilson, A.E. Bayly & D.W. York. (2005) Influence of Process Parameters on the Tapping Characteristics of High Shear Mixer Agglomerates Made with Ultra-High Viscosity Binders. Chemical Engineering Research and Design 83:1, pages 7-23.
Crossref
Crossref
Ravindra Kamble, Manish Maheshwari, Anant Paradkar & Shivajirao Kadam. (2004) Melt solidification technique: Incorporation of higher wax content in ibuprofen beads. AAPS PharmSciTech 5:4, pages 75-83.
Crossref
Crossref
Atmaram Pawar, Anant Paradkar, Shivajirao Kadam & Kakasaheb Mahadik. (2004) Agglomeration of ibuprofen with talc by novel crystallo-co-agglomeration technique. AAPS PharmSciTech 5:4, pages 30-35.
Crossref
Crossref
E Pallagi, K Vass, K Pintye-H?di, P K?saJr.Jr., G Falkay, I Er?s & P Szab?-R?v?sz. (2004) Iron(II) sulfate release from drop-formed lipophilic matrices developed by special hot-melt technology. European Journal of Pharmaceutics and Biopharmaceutics 57:2, pages 287-294.
Crossref
Crossref
Anant Paradkar, Manish Maheshwari, Amit Kumar Tyagi, Bhaskar Chauhan & S. S. Kadam. (2003) Preparation and characterization of flurbiprofen beads by melt solidification technique. AAPS PharmSciTech 4:4, pages 514-522.
Crossref
Crossref
Kaspar van den Dries, Onno M. de Vegt, Vincent Girard & Herman Vromans. (2003) Granule breakage phenomena in a high shear mixer; influence of process and formulation variables and consequences on granule homogeneity. Powder Technology 133:1-3, pages 228-236.
Crossref
Crossref
Anant R Paradkar, Manish Maheshwari, Anant R Ketkar & Bhaskar Chauhan. (2003) Preparation and evaluation of ibuprofen beads by melt solidification technique. International Journal of Pharmaceutics 255:1-2, pages 33-42.
Crossref
Crossref
Jamila Hamdani, André J Moës & Karim Amighi. (2002) Development and evaluation of prolonged release pellets obtained by the melt pelletization process. International Journal of Pharmaceutics 245:1-2, pages 167-177.
Crossref
Crossref
Dario Voinovich, Mariarosa Moneghini, Beatrice Perissutti & Erica Franceschinis. (2001) Melt pelletization in high shear mixer using a hydrophobic melt binder: influence of some apparatus and process variables. European Journal of Pharmaceutics and Biopharmaceutics 52:3, pages 305-313.
Crossref
Crossref
Torben Schæfer. (2001) Growth mechanisms in melt agglomeration in high shear mixers. Powder Technology 117:1-2, pages 68-82.
Crossref
Crossref
Simon M. Iveson, James D. Litster, Karen Hapgood & Bryan J. Ennis. (2001) Nucleation, growth and breakage phenomena in agitated wet granulation processes: a review. Powder Technology 117:1-2, pages 3-39.
Crossref
Crossref
Anita Johansen & Torben Schæfer. (2001) Effects of interactions between powder particle size and binder viscosity on agglomerate growth mechanisms in a high shear mixer. European Journal of Pharmaceutical Sciences 12:3, pages 297-309.
Crossref
Crossref
Kieran J Crowley, Robert T Forbes, Peter York, Håkan Nyqvist & Ola Camber. (2000) Drug-fatty acid salt with wax-like properties employed as binder in melt granulation. International Journal of Pharmaceutics 211:1-2, pages 9-17.
Crossref
Crossref
P.C Knight, A Johansen, H.G Kristensen, T Sch?fer & J.P.K Seville. (2000) An investigation of the effects on agglomeration of changing the speed of a mechanical mixer. Powder Technology 110:3, pages 204-209.
Crossref
Crossref
R Thies & P Kleinebudde. (2000) Melt pelletisation of a hygroscopic drug in a high shear mixer. European Journal of Pharmaceutical Sciences 10:2, pages 103-110.
Crossref
Crossref
D Voinovich, B Campisi, M Moneghini, C Vincenzi & R Phan-Tan-Luu. (1999) Screening of high shear mixer melt granulation process variables using an asymmetrical factorial design. International Journal of Pharmaceutics 190:1, pages 73-81.
Crossref
Crossref
R Thies & P Kleinebudde. (1999) Melt pelletisation of a hygroscopic drug in a high shear mixer. International Journal of Pharmaceutics 188:2, pages 131-143.
Crossref
Crossref
Helle Eliasen, H.Gjelstrup Kristensen & Torben Schæfer. (1999) Electrostatic charging during a melt agglomeration process. International Journal of Pharmaceutics 184:1, pages 85-96.
Crossref
Crossref
Anita Johansen, Torben Schæfer & H Gjelstrup Kristensen. (1999) Evaluation of melt agglomeration properties of polyethylene glycols using a mixer torque rheometer. International Journal of Pharmaceutics 183:2, pages 155-164.
Crossref
Crossref
B Campisi, D Vojnovic, D Chicco & R Phan-Tan-Luu. (1999) Melt granulation in a high shear mixer: optimization of mixture and process variables using a combined experimental design. Chemometrics and Intelligent Laboratory Systems 48:1, pages 59-70.
Crossref
Crossref
Richard Turton, Gabriel I. Tardos & Bryan J. Ennis. 1999. Fluidization, Solids Handling, and Processing. Fluidization, Solids Handling, and Processing
331
434
.
Helle Eliasen, Torben Schæfer & H. Gjelstrup Kristensen. (1998) Effects of binder rheology on melt agglomeration in a high shear mixer. International Journal of Pharmaceutics 176:1, pages 73-83.
Crossref
Crossref
Gabriel I. Tardos, M. Irfan Khan & Paul R. Mort. (1997) Critical parameters and limiting conditions in binder granulation of fine powders. Powder Technology 94:3, pages 245-258.
Crossref
Crossref
Henning G. Kristensen. (1996) Particle agglomeration in high shear mixers. Powder Technology 88:3, pages 197-202.
Crossref
Crossref
Torben Schæfer. (1996) Melt pelletization in a high shear mixer. X. Agglomeration of binary mixtures. International Journal of Pharmaceutics 139:1-2, pages 149-159.
Crossref
Crossref
Torben Schæfer & Christina Mathiesen. (1996) Melt pelletization in a high shear mixer. VIII. Effects of binder viscosity. International Journal of Pharmaceutics 139:1-2, pages 125-138.
Crossref
Crossref
Torben Sch?fer & Christina Mathiesen. (1996) Melt pelletization in a high shear mixer. IX. Effects of binder particle size. International Journal of Pharmaceutics 139:1-2, pages 139-148.
Crossref
Crossref
Torben Sch?fer. (1996) Melt pelletization in a high shear mixer VI. Agglomeration of a cohesive powder. International Journal of Pharmaceutics 132:1-2, pages 221-230.
Crossref
Crossref
H.G. Kristensen. 1995. Advances in Pharmaceutical Sciences Volume 7. Advances in Pharmaceutical Sciences Volume 7
221
272
.
Torben Schæfer, Birgitte Taagegaard, Lars Juul Thomsen & H. Gjelstrup Kristensen. (1993) Melt pelletization in a high shear mixer. V. Effects of apparatus variables. European Journal of Pharmaceutical Sciences 1:3, pages 133-141.
Crossref
Crossref
Torben Sch?fer, Birgitte Taagegaard, Lars Juul Thomsen & H. Gjelstrup Kristensen. (1993) Melt pelletization in a high shear mixer. IV. Effects of process variables in a laboratory scale mixer. European Journal of Pharmaceutical Sciences 1:3, pages 125-131.
Crossref
Crossref