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Drug Development and Industrial Pharmacy Volume 22, 1996 - Issue 6
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Research Article

Pharmaceutical Development of (Investigational) Anticancer Agents for Parenteral Use-A Review

J. D. Jonkman-De Vries Department of Pharmacy, Slotervaart Hospital/Netherlands Cancer Institute, Louwesweg 6, 1066 EC, Amsterdam, The Netherlands
,
K. P. Flora Division of Research and Testing, Center for Drug Evaluation and Research, Food and Drug Administration, 8301 Muirkirk Road, Laurel, Maryland, 20708, USA
,
A. Bult Department of Pharmaceutical Analysis, Faculty of Pharmacy, Utrecht University, Sorbonnelaan 16, 3584 CA, Utrecht, The Netherlands
&
J. H. Beijnen Department of Pharmacy, Slotervaart Hospital/Netherlands Cancer Institute, Louwesweg 6, 1066 EC, Amsterdam, The Netherlands; Department of Pharmaceutical Analysis, Faculty of Pharmacy, Utrecht University, Sorbonnelaan 16, 3584 CA, Utrecht, The Netherlands
Pages 475-494 | Published online: 20 Oct 2008

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Ajazuddin, Amit Alexander, Basant Amarji & Parijat Kanaujia. (2013) Synthesis, characterization and in vitro studies of pegylated melphalan conjugates. Drug Development and Industrial Pharmacy 39:7, pages 1053-1062.
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Andrey E. Shchekotikhin, Helen M. Treshalina, Michael I. Treshchalin, Eleonora R. Pereverzeva, Helen B. Isakova & Alexander S. Tikhomirov. (2020) Experimental Evaluation of Anticancer Efficiency and Acute Toxicity of Anthrafuran for Oral Administration. Pharmaceuticals 13:5, pages 81.
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Bijal Vyas, Sadafara A. Pillai, Debes Ray, Vinod K. Aswal, Mu-Rong Wang, Li-Jen Chen & Pratap Bahadur. (2020) Interactions of alkyltriphenyl phosphonium based ionic liquids with block copolymer microstructures: A multitechnique study. Journal of Molecular Liquids 300, pages 112341.
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Rajapaksha Dewage Asanka Amith Rajapaksha. 2020. Polymer Nanocomposite-Based Smart Materials. Polymer Nanocomposite-Based Smart Materials 121 147 .
Urjita Sheth & Anita Bahadur. (2018) In-vitro evaluation of cytotoxic and antioxidant properties of drugs solubilized in EO-PO star block copolymer micelles. Colloids and Surfaces B: Biointerfaces 171, pages 343-350.
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Faiyaz Shakeel, Fars K. Alanazi, Mohammad Raish, Nazrul Haq, Awwad A. Radwan & Ibrahim A. Alsarra. (2015) Pharmacokinetic and in vitro cytotoxic evaluation of cholesterol-rich nanoemulsion of cholesteryl-succinyl-5-fluorouracil. Journal of Molecular Liquids 211, pages 164-168.
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Zaheer Ahmad, Afzal Shah, Muhammad Siddiq & Heinz-Bernhard Kraatz. (2014) Polymeric micelles as drug delivery vehicles. RSC Adv. 4:33, pages 17028-17038.
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A. Parmar, P. Parekh & P. Bahadur. (2013) Solubilization and Release of a Model Drug Nimesulide from PEO?PPO?PEO Block Copolymer Core?Shell Micelles: Effect of Size of PEO Blocks. Journal of Solution Chemistry 42:1, pages 80-101.
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Madhu S. Surapaneni, Sudip K. Das & Nandita G. Das. (2012) Designing Paclitaxel Drug Delivery Systems Aimed at Improved Patient Outcomes: Current Status and Challenges. ISRN Pharmacology 2012, pages 1-15.
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Alaadin Alayoubi, Seetharama D. Satyanarayanajois, Paul W. Sylvester & Sami Nazzal. (2012) Molecular modelling and multisimplex optimization of tocotrienol-rich Self Emulsified Drug Delivery Systems. International Journal of Pharmaceutics 426:1-2, pages 153-161.
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Glen S. Kwon. 2012. Multifunctional Nanoparticles for Drug Delivery Applications. Multifunctional Nanoparticles for Drug Delivery Applications 133 152 .
Justin R. Hughey & James W. McGinity. 2012. Formulating Poorly Water Soluble Drugs. Formulating Poorly Water Soluble Drugs 569 602 .
Shayne Cox GadArkadiusz Z. Dudek & Steven F. Powell. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia.
Ajit S. Narang & Sailesh Varia. (2011) Role of tumor vascular architecture in drug delivery. Advanced Drug Delivery Reviews 63:8, pages 640-658.
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Ji Young Kim, Sungwon Kim, Rodolfo Pinal & Kinam Park. (2011) Hydrotropic polymer micelles as versatile vehicles for delivery of poorly water-soluble drugs. Journal of Controlled Release 152:1, pages 13-20.
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Yogesh Kadam, Usha Yerramilli, Anita Bahadur & Pratap Bahadur. (2011) Micelles from PEO–PPO–PEO block copolymers as nanocontainers for solubilization of a poorly water soluble drug hydrochlorothiazide. Colloids and Surfaces B: Biointerfaces 83:1, pages 49-57.
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Thórdís Kristmundsdóttir, Halldóra Aesa Aradóttir, Kristín Ingólfsdóttir & Helga M Ögmundsdóttir. (2002) Solubilization of the lichen metabolite (+)-usnic acid for testing in tissue culture. Journal of Pharmacy and Pharmacology 54:11, pages 1447-1452.
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Ajit S. Narang & Divyakant S. Desai. 2009. Pharmaceutical Perspectives of Cancer Therapeutics. Pharmaceutical Perspectives of Cancer Therapeutics 49 92 .
Shyam Karki, Orn Almarsson, Lian-Feng Huang & Jinquan Dong. 2008. Water-Insoluble Drug Formulation, Second Edition. Water-Insoluble Drug Formulation, Second Edition 113 132 .
John Cannon, Sophia Paspal & Rong (Ron) Liu. 2008. Water-Insoluble Drug Formulation, Second Edition. Water-Insoluble Drug Formulation, Second Edition 375 415 .
Scott R. Croy & Glen S. Kwon. (2005) Polysorbate 80 and Cremophor EL Micelles Deaggregate and Solubilize Nystatin at the Core–Corona Interface. Journal of Pharmaceutical Sciences 94:11, pages 2345-2354.
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Th?rd?s Kristmundsd?ttir, Elsa J?nsd?ttir, Helga M. ?gmundsd?ttir & Krist?n Ing?lfsd?ttir. (2005) Solubilization of poorly soluble lichen metabolites for biological testing on cell lines. European Journal of Pharmaceutical Sciences 24:5, pages 539-543.
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Serena D. Webb, Jeffrey L. Cleland, John F. Carpenter & Theodore W. Randolph. (2003) Effects of annealing lyophilized and spray‐lyophilized formulations of recombinant human interferon‐γ. Journal of Pharmaceutical Sciences 92:4, pages 715-729.
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Michael J. Akers. (2002) Excipient–Drug Interactions in Parenteral Formulations. Journal of Pharmaceutical Sciences 91:11, pages 2283-2300.
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Bastiaan Nuijen, Marjan Bouma, Jan H.M. Schellens & Jos H. Beijnen. (2001) Progress in the Development of Alternative Pharmaceutical Formulations of Taxanes. Investigational New Drugs 19:2, pages 143-153.
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B Nuijen, M Bouma, C Manada, J M Jimeno, J HM Schellens, A Bult & J H Beijnen. (2000) Pharmaceutical development of anticancer agents derived from marine sources. Anti-Cancer Drugs 11:10, pages 793-811.
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O van Tellingen, M T Huizing, V R Nannan Panday, J H M Schellens, W J Nooijen & J H Beijnen. (1999) Cremophor EL causes (pseudo-) non-linear pharmacokinetics of paclitaxel in patients. British Journal of Cancer 81:2, pages 330-335.
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Jetske M.Meerum Terwogt, Jan H.M. Schellens, Wim W.ten Bokkel Huinink & Jos H. Beijnen. (1999) Clinical pharmacology of anticancer agents in relation to formulations and administration routes. Cancer Treatment Reviews 25:2, pages 83-102.
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J.M. Meerum Terwogt, B. Nuijen, W.W. Ten Bokkel Huinink & J.H. Beijnen. (1997) Alternative formulations of paclitaxel. Cancer Treatment Reviews 23:2, pages 87-95.
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