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Research Article

Preparation and Evaluation of Sustained-Release Solid Dispersions of Drugs with Eudragit Polymers

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Pages 1043-1054 | Published online: 20 Oct 2008

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Vivek S. Dave, Raafat M. Fahmy, Dennis Bensley & Stephen W. Hoag. (2012) Eudragit® RS PO/RL PO as rate-controlling matrix-formers via roller compaction: Influence of formulation and process variables on functional attributes of granules and tablets. Drug Development and Industrial Pharmacy 38:10, pages 1240-1253.
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Mine Ozyazici, Ferhan Sevgi, Cetin Pekcetin, Buket Sarpas & Safak Sayin. (2012) Sustained release spherical agglomerates of polymethacrylates containing mefenamic acid: in vitro release, micromeritic properties and histological studies. Pharmaceutical Development and Technology 17:4, pages 483-893.
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Zahoor Ahmad & GK Khuller. (2008) Alginate-based sustained release drug delivery systems for tuberculosis. Expert Opinion on Drug Delivery 5:12, pages 1323-1334.
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Giovanni Filippo Palmieri, Simona Michelini, Piera Di Martino & Sante Martelli. (2000) Polymers with pH-Dependent Solubility: Possibility of Use in the Formulation of Gastroresistant and Controlled-Release Matrix Tablets. Drug Development and Industrial Pharmacy 26:8, pages 837-845.
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B. Sreenivasa Rao & K. V. Ramana Murthy. (2000) Preparation and In Vitro Evaluation of Chitosan Matrices Cross-Linked by Formaldehyde Vapors. Drug Development and Industrial Pharmacy 26:10, pages 1085-1090.
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M. El Miz, M. Loutou, M. Aaddouz, A. Tahani, E. Mejdoubi, S. Jodeh, K. Azzaoui & B. Hammouti. (2023) Thermal release of thymol encapsulated into sodium, organic and pillared modified clay matrixes. Chemical Papers.
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Andréia Bagliotti Meneguin, Hernane da Silva Barud, Rafael Miguel Sábio, Paula Zanin de Sousa, Karyn Fernanda Manieri, Luís Alexandre Pedro de Freitas, Guilherme Pacheco, Jovan Duran Alonso & Marlus Chorilli. (2020) Spray-dried bacterial cellulose nanofibers: A new generation of pharmaceutical excipient intended for intestinal drug delivery. Carbohydrate Polymers 249, pages 116838.
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Cristina Yus, Silvia Irusta, Victor Sebastian & Manuel Arruebo. (2020) Controlling Particle Size and Release Kinetics in the Sustained Delivery of Oral Antibiotics Using pH-Independent Mucoadhesive Polymers. Molecular Pharmaceutics 17:9, pages 3314-3327.
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Shuang Guo, Guanhua Wang, Tong Wu, Feifei Bai, Jinghua Xu & Xiangrong Zhang. (2017) Solid dispersion of berberine hydrochloride and Eudragit ® S100: Formulation, physicochemical characterization and cytotoxicity evaluation. Journal of Drug Delivery Science and Technology 40, pages 21-27.
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Yuanhui Ji, Max Lemberg, Anke Prudic, Raphael Paus & Gabriele Sadowski. (2017) Modeling and analysis of dissolution of paracetamol/Eudragit ® formulations. Chemical Engineering Research and Design 121, pages 22-31.
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Ndidi C. Ngwuluka, Yahya E. Choonara, Pradeep Kumar, Lisa C. du Toit, Riaz A. Khan & Viness Pillay. (2014) A novel pH‐responsive interpolyelectrolyte hydrogel complex for the oral delivery of levodopa. Part I. IPEC modeling and synthesis. Journal of Biomedical Materials Research Part A 103:3, pages 1077-1084.
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R. I. Mustafin. (2011) Interpolymer combinations of chemically complementary grades of Eudragit copolymers: a new direction in the design of peroral solid dosage forms of drug delivery systems with controlled release (review). Pharmaceutical Chemistry Journal 45:5.
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Rouslan I. Moustafine, Valerija L. Bobyleva, Aleksandra V. Bukhovets, Venera R. Garipova, Tatyana V. Kabanova, Vera A. Kemenova & Guy Van Den Mooter. (2011) Structural Transformations During Swelling of Polycomplex Matrices Based on Countercharged (meth)acrylate Copolymers (EudragitR EPO/EudragitR L 100-55). Journal of Pharmaceutical Sciences 100:3, pages 874-885.
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Letícia Cruz, Evelise Assumpção, Sérgio F. Andrade, Daniela J. Conrado, Irene C. Kulkamp, Sílvia S. Guterres & Adriana R. Pohlmann. (2010) Gastroresistant microparticles containing sodium alendronate prevent the bone loss in ovariectomized rats. European Journal of Pharmaceutical Sciences 40:5, pages 441-447.
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Kiran Sonaje, Yi-Jia Chen, Hsin-Lung Chen, Shiaw-Pyng Wey, Jyuhn-Huarng Juang, Ho-Ngoc Nguyen, Chia-Wei Hsu, Kun-Ju Lin & Hsing-Wen Sung. (2010) Enteric-coated capsules filled with freeze-dried chitosan/poly(?-glutamic acid) nanoparticles for oral insulin delivery. Biomaterials 31:12, pages 3384-3394.
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Ruchi Tiwari, Birendra Srivastava, Gaurav Tiwari & Awanik Rai. (2009) Extended release promethazine HCl using acrylic polymers by freeze-drying and spray-drying techniques: formulation considerations. Brazilian Journal of Pharmaceutical Sciences 45:4, pages 829-840.
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Laila F. A. Asghar, Chetan B. Chure & Sajeev Chandran. (2009) Colon Specific Delivery of Indomethacin: Effect of Incorporating pH Sensitive Polymers in Xanthan Gum Matrix Bases. AAPS PharmSciTech 10:2, pages 418-429.
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Hamdy Abdelkader, Ossama Youssef Abdalla & Hesham Salem. (2008) Formulation of Controlled-Release Baclofen Matrix Tablets II: Influence of Some Hydrophobic Excipients on the Release Rate and In Vitro Evaluation. AAPS PharmSciTech 9:2, pages 675-683.
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Sunita Dahiya, Kamla Pathak & Ruchi Sharma. (2008) Development of Extended Release Coevaporates and Coprecipitates of Promethazine HCl with Acrylic Polymers: Formulation Considerations. CHEMICAL & PHARMACEUTICAL BULLETIN 56:4, pages 504-508.
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Lisa Claire du Toit, Viness Pillay & Michael Paul Danckwerts. (2006) Tuberculosis chemotherapy: current drug delivery approaches. Respiratory Research 7:1.
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A.R. Mullaicharam & R.S.R. Murthy. (2004) Lung accumulation of niosome-entrapped rifampicin following intravenous and intratracheal administration in the rat. Journal of Drug Delivery Science and Technology 14:2, pages 99-104.
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Bashar M. Al-Taani & Bassam M. Tashtoush. (2003) Effect of microenvironment pH of swellable and erodable buffered matrices on the release characteristics of diclofenac sodium. AAPS PharmSciTech 4:3, pages 110-115.
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S Azarmi, J Farid, A Nokhodchi, S.M Bahari-Saravi & H Valizadeh. (2002) Thermal treating as a tool for sustained release of indomethacin from Eudragit RS and RL matrices. International Journal of Pharmaceutics 246:1-2, pages 171-177.
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B.Sreenivasa Rao & K.V.Ramana Murthy. (2002) Studies on rifampicin release from ethylcellulose coated nonpareil beads. International Journal of Pharmaceutics 231:1, pages 97-106.
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B Sreenivasa Rao, A Seshasayana, S.V Pardha Saradhi, N Ravi Kumar, Cheruvu P.S Narayan & K.V Ramana Murthy. (2001) Correlation of ‘in vitro’ release and ‘in vivo’ absorption characteristics of rifampicin from ethylcellulose coated nonpareil beads. International Journal of Pharmaceutics 230:1-2, pages 1-9.
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