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Research Article

Influence of Propellant Composition on Drug Delivery from a Pressurized Metered-Dose Inhaler

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Pages 763-770 | Published online: 20 Oct 2008

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Read on this site (6)

Bing Zhu, Daniela Traini & Paul Young. (2015) Aerosol particle generation from solution-based pressurized metered dose inhalers: a technical overview of parameters that influence respiratory deposition. Pharmaceutical Development and Technology 20:8, pages 897-910.
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Bing Zhu, Daniela Traini, Hak-Kim Chan & Paul M. Young. (2013) The effect of ethanol on the formation and physico-chemical properties of particles generated from budesonide solution-based pressurized metered-dose inhalers. Drug Development and Industrial Pharmacy 39:11, pages 1625-1637.
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Kevin P. O’Donnell & Robert O. Williams$suffix/text()$suffix/text(). (2013) Pulmonary dispersion formulations: The impact of dispersed powder properties on pressurized metered dose inhaler stability. Drug Development and Industrial Pharmacy 39:3, pages 413-424.
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Philippe Rogueda. (2005) Novel hydrofluoroalkane suspension formulations for respiratory drug delivery. Expert Opinion on Drug Delivery 2:4, pages 625-638.
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Robert O. Williams$suffix/text()$suffix/text(), Akshaya M. Patel, Melisa K. Barron & True L. Rogers. (2001) Investigation of Some Commercially Available Spacer Devices for the Delivery of Glucocorticoid Steroids from a pMDI. Drug Development and Industrial Pharmacy 27:5, pages 401-412.
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Robert O. Williams, Judith Brown & Jie Liu. (1999) Influence of Micronization Method on the Performance of a Suspension Triamcinolone Acetonide Pressurized Metered-Dose Inhaler Formulation. Pharmaceutical Development and Technology 4:2, pages 167-179.
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Articles from other publishers (20)

Bryan J. Mathis, Misa Kusumoto, Alexander Zaboronok & Yuji Hiramatsu. (2021) Packaging and Delivery of Asthma Therapeutics. Pharmaceutics 14:1, pages 92.
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Amal E. Rashad, Mohammad F. Mohammad, Myriam Eckes, Thierry Porée, Rania M. Sarhan, Yasmin M. Madney & Mohamed EA. Abdelrahim. (2021) Performance of different add-on devices in dual limb non-invasive mechanically ventilated circuit. Journal of Drug Delivery Science and Technology 66, pages 102897.
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Hui Wang, David S. Nobes & Reinhard Vehring. (2019) Particle Surface Roughness Improves Colloidal Stability of Pressurized Pharmaceutical Suspensions. Pharmaceutical Research 36:3.
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Angela Mary Fonceca, William Graham Fox Ditcham, Mark L. Everard & Sunalene Devadason. 2019. Kendig's Disorders of the Respiratory Tract in Children. Kendig's Disorders of the Respiratory Tract in Children 257 271.e3 .
Hui Wang, Penny Tan, David Barona, Grace Li, Susan Hoe, David Lechuga-Ballesteros, David S. Nobes & Reinhard Vehring. (2018) Characterization of the suspension stability of pharmaceuticals using a shadowgraphic imaging method. International Journal of Pharmaceutics 548:1, pages 128-138.
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Hadeer S. Harb, Ahmed A. Elberry, Hoda Rabea, Maha Fathy & Mohamed E.A. Abdelrahim. (2017) Is Combihaler usable for aerosol delivery in single limb non-invasive mechanical ventilation?. Journal of Drug Delivery Science and Technology 40, pages 28-34.
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Ziyun Shan, Yinhe Tan, Lingzhen Qin, Ge Li, Xin Pan, Zhouhua Wang, Xiu Yu, Qinruo Wang & Chuanbin Wu. (2014) Formulation and evaluation of novel reverse microemulsions containing salmon calcitonin in hydrofluoroalkane propellants. International Journal of Pharmaceutics 466:1-2, pages 390-399.
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Alessandro Saadat, Bing Zhu, Mehra Haghi, Gregory King, Gaia Colombo, Paul M Young & Daniela Traini. (2014) The formulation, chemical and physical characterisation of clarithromycin-based macrolide solution pressurised metered dose inhaler. Journal of Pharmacy and Pharmacology 66:5, pages 639-645.
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Yinhe Tan, Zhiwen Yang, Xin Pan, Meiwan Chen, Min Feng, Lili Wang, Hu Liu, Ziyun Shan & Chuanbin Wu. (2012) Stability and aerosolization of pressurized metered dose inhalers containing thymopentin nanoparticles produced using a bottom-up process. International Journal of Pharmaceutics 427:2, pages 385-392.
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Bildad K. Nyambura, Ian W. Kellaway & Kevin M.G. Taylor. (2009) Insulin nanoparticles: Stability and aerosolization from pressurized metered dose inhalers. International Journal of Pharmaceutics 375:1-2, pages 114-122.
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Josh D. Engstrom, Jasmine M. Tam, Maria A. Miller, Robert O. WilliamsIIIIII & Keith P. Johnston. (2008) Templated Open Flocs of Nanorods for Enhanced Pulmonary Delivery with Pressurized Metered Dose Inhalers. Pharmaceutical Research 26:1, pages 101-117.
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ERIK MOGALIAN & PAUL BRIAN MYRDAL. 2007. Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics. Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics 427 441 .
Sarfaraz Niazi. 2006. Handbook of Preformulation. Handbook of Preformulation 197 239 .
Hugh Smyth. 2006. Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems. Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems 225 249 .
Hugh D.C Smyth. (2003) The influence of formulation variables on the performance of alternative propellant-driven metered dose inhalers. Advanced Drug Delivery Reviews 55:7, pages 807-828.
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Vijay Joguparthi, Philip Breen, Cesar Compadre, Xiang Zhou, Larry Gann, F. Charles Hiller & Paula Anderson. (2003) Effect of Propellant on the Pharmacokinetics and Pharmacodynamics of Inhaled Albuterol in Asthmatic Subjects. Journal of Aerosol Medicine 16:1, pages 47-53.
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Mark GibsonGerry Steele. 2001. Pharmaceutical Preformulation and Formulation. Pharmaceutical Preformulation and Formulation 175 237 .
Mark GibsonPaul Wright. 2001. Pharmaceutical Preformulation and Formulation. Pharmaceutical Preformulation and Formulation 355 378 .
Keith J McDonald & Gary P Martin. (2000) Transition to CFC-free metered dose inhalers — into the new millennium. International Journal of Pharmaceutics 201:1, pages 89-107.
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Robert O Williams III, Michael A Repka & Melisa K Barron. (1999) Application of co-grinding to formulate a model pMDI suspension. European Journal of Pharmaceutics and Biopharmaceutics 48:2, pages 131-140.
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