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Original Article

PLCE1 Suppresses p53 Expression in Esophageal Cancer Cells

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Pages 236-240 | Received 24 Jan 2014, Accepted 01 Mar 2014, Published online: 25 Apr 2014

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Ya Cheng, Song-Ge Xing, Wei-Dong Jia, Mei Huang & Na-Na Bian. (2017) Low PLCE1 levels are correlated with poor prognosis in hepatocellular carcinoma. OncoTargets and Therapy 10, pages 47-54.
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Articles from other publishers (17)

Naincy R. Chandan, Alan V. Smrcka & Hoa T.N. Phan. 2022. GPCRs as Therapeutic Targets. GPCRs as Therapeutic Targets 458 520 .
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Mi Suk Park, Young Eun Lee, Hye Ran Kim, Jong Hee Shin, Hyun Wook Cho, Jun Hyung Lee & Myung Geun Shin. (2021) Phospholipase C Beta 2 Protein Overexpression Is a Favorable Prognostic Indicator in Newly Diagnosed Normal Karyotype Acute Myeloid Leukemia. Annals of Laboratory Medicine 41:4, pages 409-413.
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Xin-Guo, Yong-Yang, Jia-Qin Ma, Xi-Zou, Li-Sha Li, Yan-Hua Li, Yu-Zhen Hu & Rui-Liu. (2021) PLCε1 mediates one-lung ventilation injury by regulating the p38/RhoA/NFκB activation loop. Molecular Immunology 133, pages 135-145.
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Xiang‐Kun Wang, Xi‐Wen Liao, Cheng‐Kun Yang, Zheng‐Qian Liu, Quan‐Fa Han, Xin Zhou, Lin‐Bo Zhang, Teng Deng, Yi‐Zhen Gong, Jian‐Lu Huang, Rui Huang, Chuang‐Ye Han, Ting‐Dong Yu, Hao Su, Xin‐Ping Ye, Tao Peng & Guang‐Zhi Zhu. (2020) Oncogene PLCE1 may be a diagnostic biomarker and prognostic biomarker by influencing cell cycle, proliferation, migration, and invasion ability in hepatocellular carcinoma cell lines . Journal of Cellular Physiology 235:10, pages 7003-7017.
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Yunzhao Chen, Huahua Xin, Hao Peng, Qi Shi, Menglu Li, Jie Yu, Yanxia Tian, Xueping Han, Xi Chen, Yi Zheng, Jun Li, Zhihao Yang, Lan Yang, Jianming Hu, Xuan Huang, Zheng Liu, Xiaoxi Huang, Hong Zhou, Xiaobin Cui & Feng Li. (2020) Hypomethylation-Linked Activation of PLCE1 Impedes Autophagy and Promotes Tumorigenesis through MDM2-Mediated Ubiquitination and Destabilization of p53. Cancer Research 80:11, pages 2175-2189.
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Ziba Nariman-saleh-fam, Zahra Saadatian, Lida Nariman-Saleh-Fam, Elaheh Ouladsahebmadarek, Javad Tavakkoly-Bazzaz & Milad Bastami. (2019) An Association and Meta-Analysis of Esophageal Squamous Cell Carcinoma Risk Associated with PLCE1 rs2274223, C20orf54 rs13042395 and RUNX1 rs2014300 Polymorphisms. Pathology & Oncology Research 26:2, pages 681-692.
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Yunzhao Chen, Dandan Wang, Hao Peng, Xi Chen, Xueping Han, Jie Yu, Wenjie Wang, Lirong Liang, Zheng Liu, Yi Zheng, Jianming Hu, Lan Yang, Jun Li, Hong Zhou, Xiaobin Cui & Feng Li. (2019) Epigenetically upregulated oncoprotein PLCE1 drives esophageal carcinoma angiogenesis and proliferation via activating the PI-PLCε-NF-κB signaling pathway and VEGF-C/ Bcl-2 expression. Molecular Cancer 18:1.
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Chun Tang, Jin‐Yuan He, Chao Yu, Pei‐Jie Wang, Shao‐Hong Huang, Hong‐Jie Zheng, Dong‐Qing Yan, Jun‐Hang Zhang & Yun Li. (2019) Retracted : MicroRNA‐145 performs as a tumor suppressor in human esophageal squamous cell carcinoma by targeting phospholipase C epsilon 1 . Journal of Cellular Biochemistry 120:6, pages 10678-10687.
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Qingfa Chen, Yu Wang, Yan Xu, Hai Lin, Fangxi Xue & Xingtian Chen. (2019) Correlation between PLCE1 rs2274223 variant and digestive tract cancer: A meta‐analysis . Molecular Genetics & Genomic Medicine 7:4, pages e00589.
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Xiaobin Cui, Kaige Wang, Xinqian Yang, Hao Peng, Xi Chen, Huahua Xin, Yanxia Tian, Yunzhao Chen & Feng Li. (2017) Comprehensive bioinformation analysis of the miRNA of PLCE1 knockdown in esophageal squamous cell carcinoma. Molecular and Cellular Biochemistry 442:1-2, pages 111-127.
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Yongzhu Li & Chunyan Luan. (2018) PLCE1 Promotes the Invasion and Migration of Esophageal Cancer Cells by Up-Regulating the PKCα/NF-κB Pathway . Yonsei Medical Journal 59:10, pages 1159.
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Xiaobin Cui, Huahua Xin, Hao Peng & Yunzhao Chen. (2017) Comprehensive bioinformatics analysis of the mRNA profile of PLCE1 knockdown in esophageal squamous cell carcinoma. Molecular Medicine Reports 16:5, pages 5871-5880.
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Xiwen Liao, Chuangye Han, Wei Qin, Xiaoguang Liu, Long Yu, Guangzhi Zhu, Tingdong Yu, Sicong Lu, Hao Su, Zhen Liu, Zhiwei Chen, Chengkun Yang, Ketuan Huang, Zhengtao Liu, Yu Liang, Jianlu Huang, Jiahong Dong, Lequn Li, Xue Qin, Xinping Ye, Kaiyin Xiao, Minhao Peng & Tao Peng. (2017) PLCE1 polymorphisms and expression combined with serum AFP level predicts survival of HBV-related hepatocellular carcinoma patients after hepatectomy. Oncotarget 8:17, pages 29202-29219.
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Ana Herrero, Elizabeta Rojas, Irena Misiewicz-Krzeminska, Patryk Krzeminski & Norma Gutiérrez. (2016) Molecular Mechanisms of p53 Deregulation in Cancer: An Overview in Multiple Myeloma. International Journal of Molecular Sciences 17:12, pages 2003.
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Xiao-Bin Cui, Su Li, Ting-Ting Li, Hao Peng, Ting-Ting Jin, Shu-Mao Zhang, Chun-Xia Liu, Lan Yang, Yao-Yuan Shen, Shu-Gang Li, Na Li, Yong Li, Jian-Ming Hu, Jin-Fang Jiang, Jing Suo, Yan Qi, Wei-Hua Liang, Liang-Hai Wang, Hong-Wei Dang, Li Li, Wei-Wei Cao, Yutao Wei, Laibo Yin, Chuan-Yue Wu, Xiang-Lin Yuan, Hong Zhou, Yu Zheng, Yun-Zhao Chen & Feng Li. (2015) Targeting oncogenic PLCE1 by miR-145 impairs tumor proliferation and metastasis of esophageal squamous cell carcinoma. Oncotarget 7:2, pages 1777-1795.
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Zhenzong Du, Kui Ma, Xiaolin Sun, Angui Li, Haiyong Wang, Lifei Zhang, Feng Lin, Xiaoyan Feng & Jianfei Song. (2015) Methylation of RASSF1A gene promoter and the correlation with DNMT1 expression that may contribute to esophageal squamous cell carcinoma. World Journal of Surgical Oncology 13:1.
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