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Original Article

B7-H3 was Highly Expressed in Human Primary Hepatocellular Carcinoma and Promoted Tumor Progression

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Pages 262-271 | Received 28 Aug 2013, Accepted 26 Mar 2014, Published online: 30 Apr 2014

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Theodoros Michelakos, Filippos Kontos, Omar Barakat, Luke Maggs, Joseph H. Schwab, Cristina R. Ferrone & Soldano Ferrone. (2021) B7-H3 targeted antibody-based immunotherapy of malignant diseases. Expert Opinion on Biological Therapy 21:5, pages 587-602.
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Rui Cheng, Bi Wang, Xin-ran Cai, Zhi-shan Chen, Qiang Du, Liang-yi Zhou, Jing-min Ye & Yan-ling Chen. (2020) CD276 Promotes Vasculogenic Mimicry Formation in Hepatocellular Carcinoma via the PI3K/AKT/MMPs Pathway. OncoTargets and Therapy 13, pages 11485-11498.
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Peixin Dong, Ying Xiong, Junming Yue, Sharon J. B. Hanley & Hidemichi Watari. (2018) B7H3 As a Promoter of Metastasis and Promising Therapeutic Target. Frontiers in Oncology 8.
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Rui Cheng, Yongqin Chen, Haohui Zhou, Bi Wang, Qiang Du & Yanling Chen. (2018) B7‐H3 expression and its correlation with clinicopathologic features, angiogenesis, and prognosis in intrahepatic cholangiocarcinoma. APMIS 126:5, pages 396-402.
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Yu-Chen Tang, Yan Zhang, Jin Zhou, Qiaoming Zhi, Meng-Yao Wu, Fei-Ran Gong, Meng Shen, Lu Liu, Min Tao, Bairong Shen, Dong-Mei Gu, Jie Yu, Meng-Dan Xu, Yuan Gao & Wei Li. (2017) Ginsenoside Rg3 targets cancer stem cells and tumor angiogenesis to inhibit colorectal cancer progression in vivo. International Journal of Oncology.
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Fenghuang Xu, Junzhu Yi, Feifei Wang, Weiwei Wang, Zhuoya Wang, Jiangnan Xue & Xiying Luan. (2017) Involvement of soluble B7‑H3 in combination with the serum inflammatory cytokines interleukin‑17, ‑8 and ‑6 in the diagnosis of hepatocellular carcinoma. Oncology Letters.
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Yecheng Li, Xiaodong Yang, Yong Wu, Kui Zhao, Zhenyu Ye, Junjia Zhu, Xiaohui Xu, Xin Zhao & Chungen Xing. (2017) B7-H3 promotes gastric cancer cell migration and invasion. Oncotarget 8:42, pages 71725-71735.
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Lujun Chen, Quanqin Xie, Zhigang Wang, Liangrong Shi, Changping Wu & Jingting Jiang. (2016) Assessment of combined expression of B7-H3 and B7-H4 as prognostic marker in esophageal cancer patients. Oncotarget 7:47, pages 77237-77243.
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Zheng-Shi Wang, Ming Zhong, Yu-Hai Bian, Yi-Fei Mu, Shao-Lan Qin, Min-Hao Yu & Jun Qin. (2016) MicroRNA-187 inhibits tumor growth and invasion by directly targeting CD276 in colorectal cancer. Oncotarget 7:28, pages 44266-44276.
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Bo Jiang, Fen Liu, ZhiHui Liu, Ting Zhang & Dong Hua. (2016) B7-H3 increases thymidylate synthase expression via the PI3k-Akt pathway. Tumor Biology 37:7, pages 9465-9472.
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FEN LIU, TING ZHANG, SHITAO ZOU, BO JIANG & DONG HUA. (2015) B7-H3 promotes cell migration and invasion through the Jak2/Stat3/MMP9 signaling pathway in colorectal cancer. Molecular Medicine Reports 12:4, pages 5455-5460.
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Sunitha V. Bachawal, Kristin C. Jensen, Katheryne E. Wilson, Lu Tian, Amelie M. Lutz & Jürgen K. Willmann. (2015) Breast Cancer Detection by B7-H3–Targeted Ultrasound Molecular Imaging. Cancer Research 75:12, pages 2501-2509.
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Fu-Biao Kang, Ling Wang, Dong Li, Yin-Ge Zhang & Dian-Xing Sun. (2014) Hepatocellular carcinomas promote tumor-associated macrophage M2-polarization via increased B7-H3 expression. Oncology Reports.
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