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Original Articles

Changes in PKM2 Associate with Prostate Cancer Progression

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Pages 330-338 | Received 22 Aug 2013, Accepted 08 Apr 2014, Published online: 02 Jun 2014

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Jiayuan Wu, Liren Hu, Manyu Chen, Wenjun Cao, Haicong Chen & Taiping He. (2016) Pyruvate kinase M2 overexpression and poor prognosis in solid tumors of digestive system: evidence from 16 cohort studies. OncoTargets and Therapy 9, pages 4277-4288.
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Articles from other publishers (27)

Lu Zhan, Fangting Su, Qiang Li, Yueqiang Wen, Feng Wei, Zhelin He, Xiaoyan Chen, Xiang Yin, Jian Wang, Yilin Cai, Yuxia Gong, Yu Chen, Xiao Ma & Jinhao Zeng. (2023) Phytochemicals targeting glycolysis in colorectal cancer therapy: effects and mechanisms of action. Frontiers in Pharmacology 14.
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Huriye Ercan, Ulrike Resch, Felicia Hsu, Goran Mitulovic, Andrea Bileck, Christopher Gerner, Jae-Won Yang, Margarethe Geiger, Ingrid Miller & Maria Zellner. (2023) A Practical and Analytical Comparative Study of Gel-Based Top-Down and Gel-Free Bottom-Up Proteomics Including Unbiased Proteoform Detection. Cells 12:5, pages 747.
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Ling Zhang, Bin Wang, Zhi-Shun Wang, Yong-Lian Guo & Hao Shen. (2022) Construction of Glycolytic Regulator Gene Signature to Predict the Prognosis and Tumor Immune Cell Infiltration Levels for Prostate Cancer. Computational and Mathematical Methods in Medicine 2022, pages 1-13.
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Saleha Anwar, Anas Shamsi, Taj Mohammad, Asimul Islam & Md. Imtaiyaz Hassan. 2022. Protein Kinase Inhibitors. Protein Kinase Inhibitors 199 222 .
Tomas Koltai, Stephan J. Reshkin, Fátima Baltazar & Larry Fliegel. 2021. Prostate Cancer Metabolism. Prostate Cancer Metabolism 271 294 .
Rui Zhao, Lei Li, Jinbo Yang, Qinfeng Niu, Han Wang, Xiaodong Qin, Ning Zhu & Anchen Shi. (2019) Overexpression of Pyruvate Kinase M2 in Tumor Tissues Is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma. Pathology & Oncology Research 26:2, pages 853-860.
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Laura Boldrini, Francesca Manassero, Cesare Selli, Riccardo Bartoletti & Pinuccia Faviana. (2020) p16 and its putative interplay with metabolic factors in prostate cancer: An analysis based on public TCGA data. World Academy of Sciences Journal.
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Juan M. Jiménez-Vacas, Vicente Herrero-Aguayo, Antonio J. Montero-Hidalgo, Enrique Gómez-Gómez, Antonio C. Fuentes-Fayos, Antonio J. León-González, Prudencio Sáez-Martínez, Emilia Alors-Pérez, Sergio Pedraza-Arévalo, Teresa González-Serrano, Oscar Reyes, Ana Martínez-López, Rafael Sánchez-Sánchez, Sebastián Ventura, Elena M. Yubero-Serrano, María J. Requena-Tapia, Justo P. Castaño, Manuel D. Gahete & Raúl M. Luque. (2020) Dysregulation of the splicing machinery is directly associated to aggressiveness of prostate cancer. EBioMedicine 51, pages 102547.
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Krishna B Singh, Eun-Ryeong Hahm, Joshi J Alumkal, Lesley M Foley, T Kevin Hitchens, Sruti S Shiva, Rahul A Parikh, Bruce L Jacobs & Shivendra V Singh. (2019) Reversal of the Warburg phenomenon in chemoprevention of prostate cancer by sulforaphane. Carcinogenesis 40:12, pages 1545-1556.
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Marrocco, Altieri, Rubini, Paglia, Chichiarelli, Giamogante, Macone, Perugia, Magliocca, Gurtner, Maras, Ragno, Patsilinakos, Manganaro & Eufemi. (2019) Shmt2: A Stat3 Signaling New Player in Prostate Cancer Energy Metabolism. Cells 8:9, pages 1048.
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Rong Ma, Qing Liu, Shutao Zheng, Tao Liu, Doudou Tan & Xiaomei Lu. (2019) PKM2‐regulated STAT3 promotes esophageal squamous cell carcinoma progression via TGF‐β1‐induced EMT. Journal of Cellular Biochemistry 120:7, pages 11539-11550.
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Radivojka Bánová Vulić, Martina Zdurienčíková, Silvia Tyčiaková, Oldřich Benada, Mária Dubrovčáková, Ján Lakota & Ľudovít Škultéty. (2019) Silencing of carbonic anhydrase I enhances the malignant potential of exosomes secreted by prostatic tumour cells. Journal of Cellular and Molecular Medicine 23:5, pages 3641-3655.
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G. Comito, A. Iscaro, M. Bacci, A. Morandi, L. Ippolito, M. Parri, I. Montagnani, M. R. Raspollini, S. Serni, L. Simeoni, E. Giannoni & P. Chiarugi. (2019) Lactate modulates CD4+ T-cell polarization and induces an immunosuppressive environment, which sustains prostate carcinoma progression via TLR8/miR21 axis. Oncogene 38:19, pages 3681-3695.
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Hung-Jung Wang, Mamata Pochampalli, Ling-Yu Wang, June X Zou, Pei-Shan Li, Sheng-Chieh Hsu, Bi-Juan Wang, Shih-Han Huang, Ping Yang, Joy C. Yang, Cheng-Ying Chu, Chia-Ling Hsieh, Shian-Ying Sung, Chien-Feng Li, Clifford G. Tepper, David K. Ann, Allen C. Gao, Christopher P. Evans, Yoshihiro Izumiya, Chi-Pin Chuu, Wen-Ching Wang, Hong-Wu Chen & Hsing-Jien Kung. (2018) KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC. Oncogene 38:1, pages 17-32.
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Chenchu Lin, Travis C. Salzillo, David A. Bader, Sandi R. Wilkenfeld, Dominik Awad, Thomas L. Pulliam, Prasanta Dutta, Shivanand Pudakalakatti, Mark Titus, Sean E. McGuire, Pratip K. Bhattacharya & Daniel E. Frigo. 2019. Prostate Cancer. Prostate Cancer 185 237 .
Corinne Beinat, Tom Haywood, Yun-Sheng Chen, Chirag B. Patel, Israt S. Alam, Surya Murty & Sanjiv Sam Gambhir. (2018) The Utility of [18F]DASA-23 for Molecular Imaging of Prostate Cancer with Positron Emission Tomography. Molecular Imaging and Biology 20:6, pages 1015-1024.
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Diya Hasan, Elisabetta Gamen, Nafez Abu Tarboush, Yazan Ismail, Oleg Pak & Belal Azab. (2018) PKM2 and HIF-1α regulation in prostate cancer cell lines. PLOS ONE 13:9, pages e0203745.
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Yota Yasumizu, Hiroshi Hongo, Takeo Kosaka, Shuji Mikami, Koshiro Nishimoto, Eiji Kikuchi & Mototsugu Oya. (2018) PKM2 under hypoxic environment causes resistance to mTOR inhibitor in human castration resistant prostate cancer. Oncotarget 9:45, pages 27698-27707.
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Jian Lu, Min Chen, Sumeng Gao, Jigang Yuan, Zhu Zhu & Xiaoping Zou. (2018) LY294002 inhibits the Warburg effect in gastric cancer cells by downregulating pyruvate kinase M2. Oncology Letters.
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Xiao‐Ling Yan, Xue‐Bin Zhang, Ran Ao & Lin Guan. (2017) Retracted : Effects of shRNA‐Mediated Silencing of PKM2 Gene on Aerobic Glycolysis, Cell Migration, Cell Invasion, and Apoptosis in Colorectal Cancer Cells . Journal of Cellular Biochemistry 118:12, pages 4792-4803.
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Vincenzo N. Talesa, Ivana Ferri, Guido Bellezza, Harold D. Love, Angelo Sidoni & Cinzia Antognelli. (2017) Glyoxalase 2 Is Involved in Human Prostate Cancer Progression as Part of a Mechanism Driven By PTEN/PI3K/AKT/mTOR Signaling With Involvement of PKM2 and ERα. The Prostate 77:2, pages 196-210.
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Udensi K. Udensi & Paul B. Tchounwou. (2016) Oxidative stress in prostate hyperplasia and carcinogenesis. Journal of Experimental & Clinical Cancer Research 35:1.
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Haili Wu, Peng Yang, Wanglai Hu, Yingying Wang, Yangxu Lu, Lichao Zhang, Yongsheng Fan, Hong Xiao & Zhuoyu Li. (2016) Overexpression of PKM2 promotes mitochondrial fusion through attenuated p53 stability. Oncotarget 7:47, pages 78069-78082.
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GAOCHAO DONG, QIXING MAO, WENJIE XIA, YOUTAO XU, JIE WANG, LIN XU & FENG JIANG. (2016) PKM2 and cancer: The function of PKM2 beyond glycolysis. Oncology Letters 11:3, pages 1980-1986.
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Elisa Giannoni, Maria Letizia Taddei, Andrea Morandi, Giuseppina Comito, Maura Calvani, Francesca Bianchini, Barbara Richichi, Giovanni Raugei, Nicholas Wong, Damu Tang & Paola Chiarugi. (2015) Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs OXPHOS and prostate cancer metastatic spread. Oncotarget 6:27, pages 24061-24074.
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Wen Hu, Shi-Xun Lu, Min Li, Chao Zhang, Li-Li Liu, Jia Fu, Jie-Tian Jin, Rong-Zhen Luo, Chris Zhiyi Zhang & Jing-Ping Yun. (2015) Pyruvate kinase M2 prevents apoptosis via modulating Bim stability and associates with poor outcome in hepatocellular carcinoma. Oncotarget 6:9, pages 6570-6583.
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Zongwei Li, Peng Yang & Zhuoyu Li. (2014) The multifaceted regulation and functions of PKM2 in tumor progression. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1846:2, pages 285-296.
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