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Cancer Investigation Volume 33, 2015 - Issue 10
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ORIGINAL ARTICLE

A Phase I Study of the Hsp90 Inhibitor AUY922 plus Capecitabine for the Treatment of Patients with Advanced Solid Tumors

Johanna C. BendellSarah Cannon Research Institute/Tennessee Oncology, PLLC, Nashville, Tennessee, USACorrespondence[email protected]
,
Suzanne F. JonesSarah Cannon Research Institute, Nashville, Tennessee, USA
,
Lowell HartFlorida Cancer Specialists/SCRI, Ft. Myers, Florida, USA
,
Shubham PantOklahoma University/SCRI, Oklahoma City, Oklahoma, USA
,
Adil MoyhuddinTennessee Oncology, PLLC/SCRI, Nashville, Tennessee, USA
,
Cassie M. LaneSarah Cannon Research Institute, Nashville, Tennessee, USA
,
Chris EarwoodSarah Cannon Research Institute, Nashville, Tennessee, USA
,
Patrick MurphyTennessee Oncology, PLLC/SCRI, Nashville, Tennessee, USA
,
Jeffrey PattonTennessee Oncology, PLLC/SCRI, Nashville, Tennessee, USA
,
William C. PenleyTennessee Oncology, PLLC/SCRI, Nashville, Tennessee, USA
,
Dana ThompsonTennessee Oncology, PLLC/SCRI, Nashville, Tennessee, USA
&
Jeffrey R. InfanteTennessee Oncology, PLLC/SCRI, Nashville, Tennessee, USA
 show all
Pages 477-482 | Received 11 Jun 2015, Accepted 02 Jul 2015, Published online: 13 Oct 2015

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Li Li, Nan-Nan Chen, Qi-Dong You & Xiao-Li Xu. (2021) An updated patent review of anticancer Hsp90 inhibitors (2013-present). Expert Opinion on Therapeutic Patents 31:1, pages 67-80.
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Articles from other publishers (12)

Thomas L. Prince, Benjamin J. Lang, Yuka Okusha, Takanori Eguchi & Stuart K. Calderwood. 2023. The Networking of Chaperones by Co-Chaperones. The Networking of Chaperones by Co-Chaperones 141 158 .
Zi-Nan Li & Ying Luo. (2022) HSP90 inhibitors and cancer: Prospects for use in targeted therapies (Review). Oncology Reports 49:1.
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Maosen Huang, Linyao Cheng, SiSi Mo, Haiming Ru, Xianwei Mo & Linhai Yan. (2022) Evaluation of colorectal cancer liver metastases based on liquid biopsy combined with folate receptor– Positive circulating tumor cells and HSP90. Frontiers in Oncology 12.
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Kalliopi Ziaka & Jacqueline van der Spuy. (2022) The Role of Hsp90 in Retinal Proteostasis and Disease. Biomolecules 12:7, pages 978.
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Shuxian Yang, Haiyan Xiao & Li Cao. (2021) Recent advances in heat shock proteins in cancer diagnosis, prognosis, metabolism and treatment. Biomedicine & Pharmacotherapy 142, pages 112074.
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Marilia Barreca, Virginia Spanò, Maria Valeria Raimondi, Chiara Tarantelli, Filippo Spriano, Francesco Bertoni, Paola Barraja & Alessandra Montalbano. (2021) Recurrence of the oxazole motif in tubulin colchicine site inhibitors with anti-tumor activity. European Journal of Medicinal Chemistry Reports 1, pages 100004.
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Brittany Epp-Ducharme, Michael Dunne, Linyu Fan, James C. Evans, Lubabah Ahmed, Pauric Bannigan & Christine Allen. (2021) Heat-activated nanomedicine formulation improves the anticancer potential of the HSP90 inhibitor luminespib in vitro. Scientific Reports 11:1.
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Maxim Shevtsov, Gabriele Multhoff, Elena Mikhaylova, Atsushi Shibata, Irina Guzhova & Boris Margulis. (2019) Combination of Anti-Cancer Drugs with Molecular Chaperone Inhibitors. International Journal of Molecular Sciences 20:21, pages 5284.
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Sangkyu Park, Jeong-A Park, Jae-Hyung Jeon & Younghee Lee. (2019) Traditional and Novel Mechanisms of Heat Shock Protein 90 (HSP90) Inhibition in Cancer Chemotherapy Including HSP90 Cleavage. Biomolecules & Therapeutics 27:5, pages 423-434.
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David M. Vail, Douglas H. Thamm & Julias M. Liptak. 2019. Withrow and MacEwen's Small Animal Clinical Oncology. Withrow and MacEwen's Small Animal Clinical Oncology 251 285 .
Reyhaneh Moradi-Marjaneh, Seyed Mahdi Hassanian, Gordon A. Ferns, Amir Avan & Majid Khazaei. 2019. Heat Shock Protein 90 in Human Diseases and Disorders. Heat Shock Protein 90 in Human Diseases and Disorders 47 84 .
Anita Sveen, Jarle Bruun, Peter W. Eide, Ina A. Eilertsen, Lorena Ramirez, Astrid Murumägi, Mariliina Arjama, Stine A. Danielsen, Kushtrim Kryeziu, Elena Elez, Josep Tabernero, Justin Guinney, Hector G. Palmer, Arild Nesbakken, Olli Kallioniemi, Rodrigo Dienstmann & Ragnhild A. Lothe. (2018) Colorectal Cancer Consensus Molecular Subtypes Translated to Preclinical Models Uncover Potentially Targetable Cancer Cell Dependencies. Clinical Cancer Research 24:4, pages 794-806.
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