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Original Article

Controversies in The Basic Sciences : Is O6-Alkylguanine Necessary for Initiation of Carcinogenesis by Alkylating Agents?

Page 221 | Published online: 11 Jun 2009

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Masataka Takahashi, Katsuyoshi Mineura, Katsuo Watanabe & Kohfuku Kohda. (2000) O6-(Fluorobenzyl)Guanine and Chloroethylnitrosourea in Xenografted Rat Brain Tumor In Vivo. Acta Oncologica 39:1, pages 89-95.
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Articles from other publishers (13)

Klaus Becker, Adam D. Thomas & Bernd Kaina. (2014) Does increase in DNA repair allow “Tolerance-to-Insult” in chemical carcinogenesis? Skin tumor experiments with MGMT-overexpressing mice. Environmental and Molecular Mutagenesis 55:2, pages 145-150.
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John C. Stavridis. 2008. Oxidation: The Cornerstone of Carcinogenesis. Oxidation: The Cornerstone of Carcinogenesis 127 135 .
Asher M. Moser, Mahendra Patel, Heannie Yoo, Frank M. Balis & Mary E. Hawkins. (2000) Real-Time Fluorescence Assay for O6-Alkylguanine-DNA Alkyltransferase. Analytical Biochemistry 281:2, pages 216-222.
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Suvarchala Edara, Sreenivas Kanugula & Anthony E. Pegg. (1999) Expression of the inactive C145A mutant human O6-alkylguanine-DNA alkyltransferase in E.coli increases cell killing and mutations by N-methyl-N′-nitro-N-nitrosoguanidine. Carcinogenesis 20:1, pages 103-108.
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Stefano Corra, Katherine Kazakoff, Terence A. Lawson, Thomas E. Adrian & Parviz M. Pour. (1992) Cholecystokinin inhibits DNA alkylation induced by N-nitrosobis (2-oxopropyl)amine (BOP) in hamster pancreas. Cancer Letters 62:3, pages 251-256.
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John DiGiovanni. (1992) Multistage carcinogenesis in mouse skin. Pharmacology & Therapeutics 54:1, pages 63-128.
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Ashis K. Basu & John M. Essigmann. (1990) Site-specifically alkylated oligodeoxynucleotides: Probes for mutagenesis, DNA repair and the structural effects of DNA damage. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 233:1-2, pages 189-201.
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Anthony E. Pegg. (1990) Properties of mammalian O6-alkylguanine-DNA transferases. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 233:1-2, pages 165-175.
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B. Singer & M.K. Dosanjh. (1990) Site-directed mutagenesis for quantitation of base-base interactions at defined sites. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 233:1-2, pages 45-51.
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Matthew W. Kalnik, Benjamin F. L. Li, Peter F. Swann & Dinshaw J. Patel. (2002) O6-Ethylguanine carcinogenic lesions in DNA: an NMR study of O6etG.cntdot.T pairing in dodecanucleotide duplexes. Biochemistry 28:15, pages 6170-6181.
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Benjamin F. L. Li, Colin B. Reese & Peter F. Swann. (2002) Synthesis and characterization of oligodeoxynucleotides containing 4-O-methylthymine. Biochemistry 26:4, pages 1086-1093.
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B Singer. (1985) In vivo formation and persistence of modified nucleosides resulting from alkylating agents.. Environmental Health Perspectives 62, pages 41-48.
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William Lijinsky. (1985) The metabolism and cellular interactions of some aliphatic nitrogenous carcinogens. Cancer Letters 26:1, pages 33-42.
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