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Cancer Investigation Volume 3, 1985 - Issue 1
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Original Article

Lymphatic Delivery of Monoclonal Antibodies: Potential for Detection and Treatment of Lymph Node Metastases

John N. Weinstein Laboratory of Mathematical Biology Division of Cancer Biology and Diagnosis, National Cancer Institute National Institutes of Health, Bethesda, Maryland
,
Robert J. Parker Office of the Chief, Division of Cancer Cause and Prevention, National Cancer Institute National Institutes of Health, Bethesda, Maryland
,
Oscar D. Holton Laboratory of Mathematical Biology Division of Cancer Biology and Diagnosis, National Cancer Institute National Institutes of Health, Bethesda, Maryland
,
Andrew M. Keenan Department of Nuclear Medicine Clinical Center, National Cancer Institute National Institutes of Health, Bethesda, Maryland
,
David G. Covell Laboratory of Mathematical Biology Division of Cancer Biology and Diagnosis, National Cancer Institute National Institutes of Health, Bethesda, Maryland
,
Christopher D. V. Black Laboratory of Mathematical Biology Division of Cancer Biology and Diagnosis, National Cancer Institute National Institutes of Health, Bethesda, Maryland
&
Susan M. Sieber Office of the Chief, Division of Cancer Cause and Prevention, National Cancer Institute National Institutes of Health, Bethesda, Maryland
 show all
Pages 85-95 | Published online: 11 Jun 2009

Citations (17)

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Charles B. Davis & Peter J. Bugelski. (1998) Subcutaneous bioavailability of a PRIMATIZEDTM IgG1 Anti-Human CD4 monoclonal antibody is dose dependent in transgenic mice bearing human CD4. Drug Delivery 5:2, pages 95-100.
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C. Ingvar, K. Norrgren, S.-E. Strand, T. Brodin, P.-E. Jönsson & H.-O. Sjögren. (1990) Subcutaneous Injection of Monoclonal Antibody 96.5 Biokinetics in the nude rat heterotransplanted with malignant melanoma. Acta Oncologica 29:8, pages 1047-1053.
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Articles from other publishers (15)

Meng Qin, Lan Wang, Di Wu, Christopher K. Williams, Duo Xu, Emiko Kranz, Qi Guo, Jiaoqiong Guan, Harry V. Vinters, YooJin Lee, Yiming Xie, Yun Luo, Guibo Sun, Xiaobo Sun, Zhanlong He, Yunfeng Lu, Masakazu Kamata, Jing Wen & Irvin S. Y. Chen. (2020) Enhanced Delivery of Rituximab Into Brain and Lymph Nodes Using Timed-Release Nanocapsules in Non-Human Primates. Frontiers in Immunology 10.
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Hani A. Nabi. (1997) Antibody imaging in breast cancer. Seminars in Nuclear Medicine 27:1, pages 30-39.
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John N. Weinstein & William van Osdol. (1992) The macroscopic and microscopic pharmacology of monoclonal antibodies. International Journal of Immunopharmacology 14:3, pages 457-463.
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J.C. Roos, E.J. Derksen, A. Van Lingen, B. Postma, J.J.M. Van Der Hoeven, W. Den Hollander, M. Van Loon, S. Meijer & G.J.J. Teule. (1991) Qualitative and quantitative kinetics of submucosally administered antibody fragments in patients with rectal carcinoma: the detection of lymph node metastasis in relation to local tracer diffusion. International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology 18:1, pages 59-63.
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Hani H. Abdel-Nabi, Judith A. Ortman-Nabi, William See, John Lee, Robert Ireton, Michael Boileau, Michael W. Unger & Craig Halverson. (1990) Clinical experience with intra lymphatic administration of111In-labelled monoclonal antibody PAY 276 for the detection of pelvic nodal metastases in prostatic carcinoma. European Journal of Nuclear Medicine 16:3, pages 149-156.
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M. Bauer, R. Schulz-Wendtland & H.-A. Ladner. 1990. Therapie des Zervixkarzinoms. Therapie des Zervixkarzinoms 256 265 .
John N. Weinstein & Kenji Fujimori. 1990. Protein Design and the Development of New Therapeutics and Vaccines. Protein Design and the Development of New Therapeutics and Vaccines 359 370 .
John N. Weinstein. 1990. Cancer Imaging with Radiolabeled Antibodies. Cancer Imaging with Radiolabeled Antibodies 365 385 .
Andrew M. Keenan. (1989) Immunolymphoscintigraphy. Seminars in Nuclear Medicine 19:4, pages 322-331.
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Frank H. DeLand. (1989) A perspective of monoclonal antibodies: Past, present, and future. Seminars in Nuclear Medicine 19:3, pages 158-165.
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Alec H. Sehon. (1988) Could immunological strategies for cancer treatment be adapted for AIDS?. Clinical Immunology Newsletter 9:5, pages 77-78.
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C.D.V. Black, R.A. Kroczek, J. Barbet, J.N. Weinstein & E.M. Shevach. (1988) Induction of IL-2 receptor expression in vivo: Response to concanavalin A. Cellular Immunology 111:2, pages 420-432.
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Suzanne A. Eccles, H. P. Purvies, J. M. Styles & C. J. Dean. 1988. Cancer Metastasis. Cancer Metastasis 329 339 .
J. N. WEINSTEIN, R. R. EGER, D. G. COVELL, C. D. V. BLACK, J. MULSHINE, J. A. CARRASQUILLO, S. M. LARSON & A. M. KEENAN. (1987) The Pharmacology of Monoclonal Antibodies. Annals of the New York Academy of Sciences 507:1 Biological Ap, pages 199-210.
Crossref
J. N. Weinstein, A. M. Keenan, O. D. HoltonIIIIII, D. G. Covell, S. M. Sieber, C. D. V. Black, J. Barbet, M. J. Talley & R. J. Parker. 1985. Monoclonal Antibodies and Breast Cancer. Monoclonal Antibodies and Breast Cancer 218 232 .

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