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Original Article

A Special Role for Amsacrine in the Treatment of Acute Leukemia

Pages 607-609 | Published online: 11 Jun 2009

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Furqan Ahmad Saddique, Muniba Farhad, Sana Aslam & Matloob Ahmad. (2021) Recent synthetic methodologies for the tricyclic fused-quinoline derivatives. Synthetic Communications 51:1, pages 13-36.
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Pethaperumal Iniyavan, Anusha Avadhani, Yogendra Kumar, Arkalagud Satyanarayana Jeevan Chakravarthy, Mary Antony Palluruthiyil & Hiriyakkanavar Ila. (2022) Synthesis of novel 9‐amino /aryl/oxo‐2‐(het)arylthiazolo[4,5‐ b ]quinolines via palladium catalyzed N ‐arylation ‐cyclization protocol . Journal of Heterocyclic Chemistry.
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Bin Zhang, Ting Zhang, Tian-Yi Zhang, Ning Wang, Shan He, Bin Wu & Hai-Xiao Jin. (2020) A Novel Methoxybenzyl 5-Nitroacridone Derivative Effectively Triggers G1 Cell Cycle Arrest in Chronic Myelogenous Leukemia K562 Cells by Inhibiting CDK4/6-Mediated Phosphorylation of Rb. International Journal of Molecular Sciences 21:14, pages 5077.
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Katarzyna Nowak. (2014) A solvatochromic study of N-[4-(9-acridinylamino)-3-methoxyphenyl]methanesulfonamide hydrochloride: An experimental and theoretical approach. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 130, pages 208-213.
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Marco A. Loza-Mejía, Susana Olvera-Vázquez, Karina Maldonado-Hernández, Teresita Guadarrama-Salgado, Ignacio González-Sánchez, Fernando Rodríguez-Hernández, José D. Solano, Rogelio Rodríguez-Sotres & Alfonso Lira-Rocha. (2009) Synthesis, cytotoxic activity, DNA topoisomerase-II inhibition, molecular modeling and structure–activity relationship of 9-anilinothiazolo[5,4-b]quinoline derivatives. Bioorganic & Medicinal Chemistry 17:9, pages 3266-3277.
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Carmen Avendaño & J. Carlos Menéndez. 2008. Medicinal Chemistry of Anticancer Drugs. Medicinal Chemistry of Anticancer Drugs 199 228 .
Janusz Blasiak, Ewa Gloc, Jozef Drzewoski, Katarzyna Wozniak, Marek Zadrozny, Tomasz Skórski & Tomasz Pertynski. (2003) Free radical scavengers can differentially modulate the genotoxicity of amsacrine in normal and cancer cells. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 535:1, pages 25-34.
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F Caponigro, C Dittrich, J.B Sorensen, J.H.M Schellens, F Duffaud, L Paz Ares, D Lacombe, C de Balincourt & P Fumoleau. (2002) Phase II study of XR 5000, an inhibitor of topoisomerases I and II, in advanced colorectal cancer. European Journal of Cancer 38:1, pages 70-74.
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Bruce C. Baguley, Kevin O. Hicks & William R. Wilson. 2002. Anticancer Drug Development. Anticancer Drug Development 269 cp1 .
Bruce C. Baguley. 2002. Anticancer Drug Development. Anticancer Drug Development 1 11 .
Lynnette R. Ferguson & Bruce C. Baguley. (1996) Mutagenicity of anticancer drugs that inhibit topoisomerase enzymes. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 355:1-2, pages 91-101.
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G.J. Finlay, J.-F. Riou & B.C. Baguley. (1996) From amsacrine to DACA (N-[2-(dimethylamino)ethyl]acridine-4-carboxamide): Selectivity for topoisomerases I and II among acridine derivatives. European Journal of Cancer 32:4, pages 708-714.
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Lynnette R. Ferguson, Glenn Whiteside, Karen M. Holdaway & Bruce C. Baguley. (1996) Application of fluorescence in situ hybridisation to study the relationship between cytotoxicity, chromosome aberrations, and changes in chromosome number after treatment with the topoisomerase II inhibitor amsacrine. Environmental and Molecular Mutagenesis 27:4, pages 255-262.
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Yoshihisa Iwamoto, Lynnette R. Ferguson, Amira Pearson & Bruce C. Baguley. (1992) Photo-enhancement of the mutagenicity of 9-anilinoacridine derivatives related to the antitumour agent amsacrine. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 268:1, pages 35-41.
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