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Original Article

The Pyrazoloacridines: Approaches to the Development of a Carcinoma-Selective Cytotoxic Agent

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Pages 39-47 | Published online: 11 Jun 2009

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Bhuvaneswari Ramaswamy, Ewa Mrozek, John Philip Kuebler, Tanios Bekaii-Saab & Eric H. Kraut. (2009) Phase II trial of pyrazoloacridine (NSC#366140) in patients with metastatic breast cancer. Investigational New Drugs 29:2, pages 347-351.
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Evanthia Galanis, Jan C. Buckner, Matthew J. Maurer, Joel M. Reid, Mary J. Kuffel, Matthew M. Ames, Bernd W. Scheithauer, Julie E. Hammack, George Pipoly & Steven A. Kuross. (2005) Phase I/II trial of pyrazoloacridine and carboplatin in patients with recurrent glioma: A North Central Cancer Treatment Group trial. Investigational New Drugs 23:5, pages 495-503.
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YanPing Hu, Awtar Krishan, WeiJia Nie, Kasi S. Sridhar, Lawrence D. Mayer & Marcel Bally. (2004) Synergistic Cytotoxicity of Pyrazoloacridine with Doxorubicin, Etoposide, and Topotecan in Drug-Resistant Tumor Cells. Clinical Cancer Research 10:3, pages 1160-1169.
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E. Claire Dees, Eric K. Rowinsky, Dennis A. Noe, Seamus O'Reilly, Alex A. Adjei, Kathy Elza-Brown & Ross C. Donehower. (2003) A Phase I and Pharmacologic Study of Pyrazoloacridine and Cisplatin in Patients with Advanced Cancer. Investigational New Drugs 21:1, pages 75-84.
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Alex A. Adjei, Joel M. Reid, Charles Erlichman, Jeff A. Sloan, Henry C. Pitot, Steven R. Alberts, Richard M. Goldberg, Lorelei J. Hanson, Stacie Ruben, Scott A. Boerner, Pamela Atherton, Matthew M. Ames & Scott H. Kaufmann. (2002) A Phase I and Pharmacologic Study of Pyrazoloacridine (NSC 366140) and Carboplatin in Patients with Advanced Cancer. Investigational New Drugs 20:3, pages 297-304.
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