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Review Article

The Use of Monoclonal Antibodies (MAbs) and the Development of an Intraoperative Hand-Held Probe for Cancer Detection

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Pages 560-571 | Published online: 11 Jun 2009

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Stephen P Povoski, Ioannis S Hatzaras, Cathy M Mojzisik & Edward W Martin. (2011) Oncologic theranostics: recognition of this concept in antigen-directed cancer therapy for colorectal cancer with anti-TAG-72 monoclonal antibodies. Expert Review of Molecular Diagnostics 11:7, pages 667-670.
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Steven M. Larson. (1996) RIGS: Surgery. Talking the Talk and (just possibly) Walking the Walk. Cancer Investigation 14:6, pages 637-639.
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Maria Silvia De Feo, Viviana Frantellizzi, Luciano De Sio, Alessio Farcomeni, Giuseppe De Vincentis & Roberto Pani. (2023) Role of PET gamma detection in radioguided surgery: a systematic review. Clinical and Translational Imaging 11:6, pages 567-585.
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Raghuram Reddy, Joel Mintz, Roei Golan, Fakiha Firdaus, Roxana Ponce, Derek Van Booven, Aysswarya Manoharan, Isabelle Issa, Bonnie B. Blomberg & Himanshu Arora. (2022) Antibody Diversity in Cancer: Translational Implications and Beyond. Vaccines 10:8, pages 1165.
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Stephen P. Povoski, Cathy M. Mojzisik & Brandon J. Sullivan. 2016. Radioguided Surgery. Radioguided Surgery 371 418 .
Stephen P Povoski, Nathan C Hall, Douglas A MurreyJrJr, Chadwick L Wright & Edward W MartinJrJr. (2015) Feasibility of a multimodal 18F-FDG-directed lymph node surgical excisional biopsy approach for appropriate diagnostic tissue sampling in patients with suspected lymphoma. BMC Cancer 15:1.
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Gregg J Chapman, Stephen P Povoski, Nathan C Hall, Douglas A MurreyJrJr, Robert Lee & Edward W Martin Jr. (2014) Comparison of two threshold detection criteria methodologies for determination of probe positivity for intraoperative in situ identification of presumed abnormal 18F-FDG-avid tissue sites during radioguided oncologic surgery. BMC Cancer 14:1.
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Junbin Xu, Pengfei Shao, Ting Yue, Shiwu Zhang, Houzhu Ding, Jinkun Wang & Ronald Xu. A goggle navigation system for cancer resection surgery. A goggle navigation system for cancer resection surgery.
Stephen P Povoski, Gregg J Chapman, Douglas A Murrey, Robert Lee, Edward W Martin & Nathan C Hall. (2013) Intraoperative detection of 18F-FDG-avid tissue sites using the increased probe counting efficiency of the K-alpha probe design and variance-based statistical analysis with the three-sigma criteria. BMC Cancer 13:1.
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Stephen P. Povoski, Ioannis S. Hatzaras, Cathy M. Mojzisik, Mark W. Arnold, George H. Hinkle, Charles L. Hitchcock, Donn C. Young & Edward W. MartinJr.Jr.. (2011) Antigen-Directed Cancer Surgery for Primary Colorectal Cancer: 15-Year Survival Analysis. Annals of Surgical Oncology 19:1, pages 131-138.
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Michael Campoli, Robert Ferris, Soldano Ferrone & Xinhui Wang. (2010) Immunotherapy of Malignant Disease with Tumor Antigen–Specific Monoclonal Antibodies. Clinical Cancer Research 16:1, pages 11-20.
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Stephen P Povoski, Ryan L Neff, Cathy M Mojzisik, David M O'Malley, George H Hinkle, Nathan C Hall, Douglas A MurreyJrJr, Michael V Knopp & Edward W MartinJrJr. (2009) A comprehensive overview of radioguided surgery using gamma detection probe technology. World Journal of Surgical Oncology 7:1.
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Douglas A. MurreyJr.Jr., Eamonn E. Bahnson, Nathan C. Hall, Stephen P. Povoski, Cathy M. Mojzisik, Donn C. Young, Suhail Sharif, Morgan A. Johnson, Sherif Abdel-Misih, Edward W. MartinJr.Jr. & Michael V. Knopp. (2009) Perioperative 18F-fluorodeoxyglucose–guided imaging using the becquerel as a quantitative measure for optimizing surgical resection in patients with advanced malignancy. The American Journal of Surgery 198:6, pages 834-840.
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Amit Agrawal, Nathan C. Hall, Matthew D. Ringel, Stephen P. Povoski & Edward W. MartinJrJr. (2009) Combined Use of PerioperativeTSH‐Stimulated 18 F‐FDG PET/CT Imaging and Gamma Probe Radioguided Surgery to Localize and Verify Resection of Iodine Scan‐Negative Recurrent Thyroid Carcinoma . The Laryngoscope 118:12, pages 2190-2194.
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David E. Cohn, Nathan C. Hall, Stephen P. Povoski, Leigh G. Seamon, William B. Farrar & Edward W. MartinJr.Jr.. (2008) Novel perioperative imaging with 18F-FDG PET/CT and intraoperative 18F-FDG detection using a handheld gamma probe in recurrent ovarian cancer. Gynecologic Oncology 110:2, pages 152-157.
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Nathan C Hall, Stephen P Povoski, Douglas A Murrey, Michael V Knopp & Edward W Martin. (2007) Combined approach of perioperative 18F-FDG PET/CT imaging and intraoperative 18F-FDG handheld gamma probe detection for tumor localization and verification of complete tumor resection in breast cancer. World Journal of Surgical Oncology 5:1.
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Duxin Sun, Mark Bloomston, George Hinkle, Osama Habib Al-Saif, Nathan C. Hall, Stephen P. Povoski, Mark W. Arnold & Edward W. MartinJrJr. (2007) Radioimmunoguided surgery (RIGS), PET/CT image-guided surgery, and fluorescence image-guided surgery: Past, present, and future. Journal of Surgical Oncology 96:4, pages 297-308.
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Doreen M. Agnese, Shahab F. Abdessalam, William E. BurakJr.Jr., Mark W. Arnold, Denise Soble, George H. Hinkle, Donn Young, M. B. Khazaeli & Edward W. MartinJr.Jr.. (2004) Pilot Study Using a Humanized CC49 Monoclonal Antibody (HuCC49°CH2) to Localize Recurrent Colorectal Carcinoma. Annals of Surgical Oncology 11:2.
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Emilio Bombardieri, Gianluca Aliberti, Celine de Graaf, Ernest Pauwels & Flavio Crippa. (2001) Positron emission tomography (PET) and other nuclear medicine modalities in staging gastrointestinal cancer. Seminars in Surgical Oncology 20:2, pages 134-146.
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D Desai. (2000) Correlative Whole-Body FDG-PET and Intraoperative Gamma Detection of FDG Distribution in Colorectal Cancer. Clinical Positron Imaging 3:5, pages 189-196.
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Michael A. Morse & H. Kim Lyerly. (1999) Educational Review Cellular and Biological Therapies of Gastrointestinal Tumors: Overview of Clinical Trials. Annals of Surgical Oncology 6:2, pages 218-223.
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Efthimios A. Bakalakos & William E. BurakJr.Jr.. (1999) The Radioimmunoguided Surgery (rigs) System as a Diagnostic Tool. Surgical Oncology Clinics of North America 8:1, pages 129-144.
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Mark W. Arnold, Donn M. Young, Charles L. Hitchcock, Emilio Barberá-Guillem, Carol Nieroda & Edward W. MartinJr.Jr.. (1998) Staging of colorectal cancer. Diseases of the Colon & Rectum 41:12, pages 1482-1487.
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Edward W. Martin & Marlin O. Thurston. (1998) Intraoperative radioimmunodetection. Seminars in Surgical Oncology 15:4, pages 205-208.
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