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Original Article

Mechanisms of Action of Antiestrogens: Relevance to Clinical Benefits and Risks

Clinical Science Review

Pages 604-611 | Published online: 11 Jun 2009

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Robert W Brueggemeier. (2002) Aromatase inhibitors in breast cancer therapy. Expert Review of Anticancer Therapy 2:2, pages 181-191.
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Elavarasan Subramani, Arun Prabhu Rameshbabu, Manivannan Jothiramajayam, Bhuvaneshwaran Subramanian, Debangana Chakravorty, Gunja Bose, Mamata Joshi, Chaitali Datta Ray, Indrani Lodh, Ratna Chattopadhyay, Sudipto Saha, Anita Mukherjee, Santanu Dhara, Baidyanath Chakravarty & Koel Chaudhury. (2017) Mycobacterial heat shock protein 65 mediated metabolic shift in decidualization of human endometrial stromal cells. Scientific Reports 7:1.
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Tarun Jha, Nilanajn Adhikari, Amit Kumar Halder & Achintya Saha. 2015. Quantitative Structure-Activity Relationships in Drug Design, Predictive Toxicology, and Risk Assessment. Quantitative Structure-Activity Relationships in Drug Design, Predictive Toxicology, and Risk Assessment 400 470 .
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Yanlei Ma, Peng Zhang, Yongzhi Yang, Feng Wang & Huanlong Qin. (2012) Metabolomics in the fields of oncology: a review of recent research. Molecular Biology Reports 39:7, pages 7505-7511.
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Mohamed-Elamir F. Hegazy, Amira M. Gamal-Eldeen, Ali M. El-Halawany, Abou El-Hamd H. Mohamed & Paul W. Paré. (2012) Steroidal Metabolites Transformed by Marchantia polymorpha Cultures Block Breast Cancer Estrogen Biosynthesis. Cell Biochemistry and Biophysics 63:1, pages 85-96.
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Catherine Oakman, Leonardo Tenori, Laura Biganzoli, Libero Santarpia, Silvia Cappadona, Claudio Luchinat & Angelo Di Leo. (2011) Uncovering the metabolomic fingerprint of breast cancer. The International Journal of Biochemistry & Cell Biology 43:7, pages 1010-1020.
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Paul Goldsmith, Hayley Fenton, Gareth Morris-Stiff, Niaz Ahmad, Julie Fisher & K. Rajendra Prasad. (2010) Metabonomics: A Useful Tool for the Future Surgeon. Journal of Surgical Research 160:1, pages 122-132.
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Carlos Gueto, Juan Torres & Ricardo Vivas-Reyes. (2009) CoMFA, LeapFrog and blind docking studies on sulfonanilide derivatives acting as selective aromatase expression regulators. European Journal of Medicinal Chemistry 44:9, pages 3445-3451.
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Rona Yoffe, Yasmin Khakoo, Ira J. Dunkel, Mark Souweidane, Eric Lis & Charles Sklar. (2005) Recurrent ependymoma treated with high‐dose tamoxifen in a peripubertal female: Impact on tumor and the pituitary–ovarian axis. Pediatric Blood & Cancer 49:5, pages 758-760.
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Nigel J. Gooderham & Paul L. Carmichael. 2005. The Cancer Handbook. The Cancer Handbook.
Maneesh N. Singh, Helen F. Stringfellow, Evangelos Paraskevaidis, Pierre L. Martin-Hirsch & Francis L. Martin. (2007) Tamoxifen: Important considerations of a multi-functional compound with organ-specific properties. Cancer Treatment Reviews 33:2, pages 91-100.
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S.C. Mitchell & P.L. Carmichael. (2005) Metabonomics and the endocrine system. Molecular and Cellular Endocrinology 244:1-2, pages 10-14.
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Robert W. Brueggemeier, John C. Hackett & Edgar S. Diaz-Cruz. (2005) Aromatase Inhibitors in the Treatment of Breast Cancer. Endocrine Reviews 26:3, pages 331-345.
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Nigel J. Gooderham & Paul L. Carmichael. 2005. The Cancer Handbook. The Cancer Handbook.
Jessica C. M. Pole, Leslie I. Gold, Terry Orton, Russell Huby & Paul L. Carmichael. (2005) Gene expression changes induced by estrogen and selective estrogen receptor modulators in primary-cultured human endometrial cells: signals that distinguish the human carcinogen tamoxifen. Toxicology 206:1, pages 91-109.
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Julian L. Griffin & John P. Shockcor. (2004) Metabolic profiles of cancer cells. Nature Reviews Cancer 4:7, pages 551-561.
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Julian L. Griffin. (2004) Metabolic profiles to define the genome: can we hear the phenotypes?. Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 359:1446, pages 857-871.
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J.L Griffin, J.C.M Pole, J.K Nicholson & P.L Carmichael. (2003) Cellular environment of metabolites and a metabonomic study of tamoxifen in endometrial cells using gradient high resolution magic angle spinning 1H NMR spectroscopy. Biochimica et Biophysica Acta (BBA) - General Subjects 1619:2, pages 151-158.
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Robert W. Brueggemeier. (2002) Overview of the Pharmacology of the Aromatase Inactivator Exemestane. Breast Cancer Research and Treatment 74:2, pages 177-185.
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Robert W. Brueggemeier. (2001) Aromatase, Aromatase Inhibitors, and Breast Cancer. American Journal of Therapeutics 8:5, pages 333-344.
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