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Original Article

The Role of Integrins in Tumorigenesis and Metastasis

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Pages 329-344 | Published online: 11 Jun 2009

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Charles N Landen, Michael S Kinch & Anil K Sood. (2005) EphA2 as a target for ovarian cancer therapy. Expert Opinion on Therapeutic Targets 9:6, pages 1179-1187.
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J. Galle, I. Reibiger, M. Westermann, W. Richter & S. Löffler. (2002) Local Cell Membrane Deformations due to Receptor-Ligand Bonding as Seen by Reflection Microscopy. Cell Communication & Adhesion 9:3, pages 161-172.
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Articles from other publishers (50)

Wenjing Peng, Parvin Mirzaei, Rui Zhu, Shiyue Zhou & Yehia Mechref. (2019) Comparative Membrane N -Glycomics of Different Breast Cancer Cell Lines To Understand Breast Cancer Brain Metastasis . Journal of Proteome Research 19:2, pages 854-863.
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Ben Davidson. 2018. Serous Effusions. Serous Effusions 191 237 .
Xiaoqin Liu, Hua Tian, Hong Li, Chao Ge, Fangyu Zhao, Ming Yao & Jinjun Li. (2017) Derivate Isocorydine (d-ICD) Suppresses Migration and Invasion of Hepatocellular Carcinoma Cell by Downregulating ITGA1 Expression. International Journal of Molecular Sciences 18:3, pages 514.
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Pi-Ling Chang, Yu-Hua Hsieh, Chao-Cheng Wang, M.Margaret Juliana, Yuko Tsuruta, Laura Timares, Craig Elmets & Kang-Jey Ho. (2014) Osteopontin facilitates ultraviolet B-induced squamous cell carcinoma development. Journal of Dermatological Science 75:2, pages 121-132.
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Zhihong Wu, Yue Shen, Kebo Gong, Zhihua Wu, Tingguo Zhang, Xiaodan Zhang & Shuling Li. (2013) Increased osteopontin expression is associated with progression from vulvar precancerous lesions to vulvar squamous cell carcinoma. Archives of Gynecology and Obstetrics 289:3, pages 637-644.
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Serenus Hua, Mary Saunders, Lauren M. Dimapasoc, Seung Hyup Jeong, Bum Jin Kim, Suhee Kim, Minkyung So, Kwang-Sik Lee, Jae Han Kim, Kit S. Lam, Carlito B. Lebrilla & Hyun Joo An. (2014) Differentiation of Cancer Cell Origin and Molecular Subtype by Plasma Membrane N-Glycan Profiling. Journal of Proteome Research 13:2, pages 961-968.
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Feng Li, Ying Liu, Xuan Kan, Yong Li, Ming Liu & Jian Guang Lu. (2013) Elevated expression of integrin αv and β5 subunit in laryngeal squamous-cell carcinoma associated with lymphatic metastasis and angiogenesis. Pathology - Research and Practice 209:2, pages 105-109.
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Ben Davidson. 2012. Serous Effusions. Serous Effusions 167 203 .
Ben Davidson & Fernando Schmitt. 2012. Serous Effusions. Serous Effusions 205 223 .
Rui Zhang, Shupei Cheng, Aimin Li, Jie Sun, Yan Zhang & Xuxiang Zhang. (2011) Genome-wide screening of indicator genes for assessing the potential carcinogenic risk of Nanjing city drinking water. Ecotoxicology 20:5, pages 1033-1040.
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Rohan S. Wijesurendra, Andrew Jefferson & Robin P. Choudhury. (2010) Target: ligand interactions of the vascular endothelium. Implications for molecular imaging in inflammation. Integrative Biology 2:10, pages 467-482.
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Jian Guang Lu, Ya Nan Sun, Chao Wang, De Jun Jin & Ming Liu. (2008) Role of the αv-integrin subunit in cell proliferation, apoptosis and tumor metastasis of laryngeal and hypopharyngeal squamous cell carcinomas: a clinical and in vitro investigation. European Archives of Oto-Rhino-Laryngology 266:1, pages 89-96.
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Pi-Ling Chang, Louie Harkins, Yu-Hua Hsieh, Patricia Hicks, Kraisorn Sappayatosok, Somchai Yodsanga, Somporn Swasdison, Ann F. Chambers, Craig A. Elmets & Kang-Jey Ho. (2007) Osteopontin Expression in Normal Skin and Non-melanoma Skin Tumors. Journal of Histochemistry & Cytochemistry 56:1, pages 57-66.
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Ben Davidson, Hiep Phuc Dong, Arild Holth, Aasmund Berner & Björn Risberg. (2007) Flow cytometric immunophenotyping of cancer cells in effusion specimens: Diagnostic and research applications. Diagnostic Cytopathology 35:9, pages 568-578.
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Neveen Said, Ida Najwer & Kouros Motamed. (2007) Secreted Protein Acidic and Rich in Cysteine (SPARC) Inhibits Integrin-Mediated Adhesion and Growth Factor-Dependent Survival Signaling in Ovarian Cancer. The American Journal of Pathology 170:3, pages 1054-1063.
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Francis Fouchier, Claude Penel, Marie Pierre Montero, Patricia Bremond & Serge Champion. (2007) Integrin αvβ6 mediates HT29-D4 cell adhesion to MMP-processed fibrinogen in the presence of Mn2+. European Journal of Cell Biology 86:3, pages 143-160.
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Yu-Hua Hsieh, M. Margaret Juliana, Patricia H. Hicks, Gong Feng, Craig Elmets, Lucy Liaw & Pi-Ling Chang. (2006) Papilloma Development Is Delayed in Osteopontin-Null Mice: Implicating an Antiapoptosis Role for Osteopontin. Cancer Research 66:14, pages 7119-7127.
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K. J. McQuade, D. M. Beauvais, B. J. Burbach & A. C. Rapraeger. (2006) Syndecan-1 regulates αvβ5 integrin activity in B82L fibroblasts. Journal of Cell Science 119:12, pages 2445-2456.
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Ben Davidson, Bj?rn Risberg, Aasmund Berner, Carlos W.M. Bedrossian & Reuven Reich. (2006) The biological differences between ovarian serous carcinoma and diffuse peritoneal malignant mesothelioma. Seminars in Diagnostic Pathology 23:1, pages 35-43.
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Reuven Reich, Lina Vintman, Søren Nielsen, Janne Kærn, Carlos Bedrossian, Aasmund Berner & Ben Davidson. (2005) Differential expression of the 67 kilodalton laminin receptor in epithelioid malignant mesothelioma and carcinomas that spread to serosal cavities. Diagnostic Cytopathology 33:5, pages 332-337.
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Eva Sigstad, Hiep Phuc Dong, Søren Nielsen, Aasmund Berner, Ben Davidson & Björn Risberg. (2005) Quantitative analysis of integrin expression in effusions using flow cytometric immunophenotyping. Diagnostic Cytopathology 33:5, pages 325-331.
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Hehong Ni, Anders Bondo Dydensborg, Florence Elizabeth Herring, Nuria Basora, David Gagné, Pierre H Vachon & Jean-François Beaulieu. (2005) Upregulation of a functional form of the β4 integrin subunit in colorectal cancers correlates with c-Myc expression. Oncogene 24:45, pages 6820-6829.
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Gregor Prindull. (2005) Hypothesis: Cell plasticity, linking embryonal stem cells to adult stem cell reservoirs and metastatic cancer cells?. Experimental Hematology 33:7, pages 738-746.
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Ben Davidson, Sophya Konstantinovsky, Søren Nielsen, Hiep Phuc Dong, Aasmund Berner, Mogens Vyberg & Reuven Reich. (2004) Altered Expression of Metastasis-Associated and Regulatory Molecules in Effusions from Breast Cancer Patients. Clinical Cancer Research 10:21, pages 7335-7346.
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Mariarosaria Lovecchio, Eugenio Maiorano, Rosa A. Vacca, Giuseppe Loverro, Margherita Fanelli, Leonardo Resta, Sergio Stefanelli, Luigi Selvaggi, Ersilia Marra & Elda Perlino. (2003) ?1C Integrin Expression in Human Endometrial Proliferative Diseases. The American Journal of Pathology 163:6, pages 2543-2553.
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Zsolt Sarang, Ylva Haig, Annette Hansson, Martin Vondracek, Lars Wärngård & Roland C. Grafström. (2019) Microarray Assessment of Fibronectin, Collagen and Integrin Expression and the Role of Fibronectin–Collagen Coating in the Growth of Normal, SV40 T-antigen-immortalised and Malignant Human Oral Keratinocytes. Alternatives to Laboratory Animals 31:6, pages 575-585.
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Ben Davidson, Bj?rn Risberg, Reuven Reich & Aasmund Berner. (2003) Effusion cytology in ovarian cancer: new molecular methods as aids to diagnosis and prognosis. Clinics in Laboratory Medicine 23:3, pages 729-754.
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Ben Davidson, Iris Goldberg, Reuven Reich, Liora Tell, Hiep Phuc Dong, Claes G Trope?Bj?rn Risberg & Juri Kopolovic. (2003) ?V- and ?1-integrin subunits are commonly expressed in malignant effusions from ovarian carcinoma patients. Gynecologic Oncology 90:2, pages 248-257.
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Changshou Gao, Shenlan Mao, Francesca Ronca, Sufei Zhuang, Vito Quaranta, Peter Wirsching & Kim D Janda. (2003) De novo identification of tumor-specific internalizing human antibody–receptor pairs by phage-display methods. Journal of Immunological Methods 274:1-2, pages 185-197.
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Laura Zamurs, Normand Pouliot, Peter Gibson, Glenn Hocking & Edouard Nice. (2003) Strategies for the purification of laminin-10 for studies on colon cancer metastasis. Biomedical Chromatography 17:2-3, pages 201-211.
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Takayuki NAKAGAWA, Rina UYAMA, Emi OHASHI, Tomoko TAKAHASHI, Sung Hyeol HONG, Manabu MOCHIZUKI, Satoru MATSUNAGA, Ryouhei NISHIMURA & Nobuo SASAKI. (2002) The Expression of Sialyl Lewis X in Canine and Feline Mammary Gland Tumors. Journal of Veterinary Medical Science 64:10, pages 949-952.
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Hisakazu Fujita, Futoshi Okada, Jun-ichi Hamada, Masuo Hosokawa, Tetsuya Moriuchi, Richard Chikara Koya & Noboru Kuzumaki. (2001) Gelsolin functions as a metasatsis suppressor in B16-BL6 mouse melanoma cells and requirement of the carboxyl-terminus for its effect. International Journal of Cancer 93:6, pages 773-780.
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Shingo Miyamoto, Akiko Maruyama, Kaoru Okugawa, Kohei Akazawa, Hideo Baba, Yoshihiko Maehara & Eisuke Mekada. (2001) Loss of motility-related protein 1 (MRP1/CD9) and integrin ?3 expression in endometrial cancers. Cancer 92:3, pages 542-548.
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Michael D. Schaller. (2001) Biochemical signals and biological responses elicited by the focal adhesion kinase. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1540:1, pages 1-21.
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R.R Hantgan, M Stahle, V Del Gaizo, M Adams, T Lasher, W.G Jerome, M McKenzie & D.S Lyles. (2001) αIIb’s cytoplasmic domain is not required for ligand-induced clustering of integrin αIIbβ3. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1540:1, pages 82-95.
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Josef Vormoor, Gudrun Baersch, Stephan Decker, Marc Hotfilder, Karl-Ludwig Sch?fer, Lutz Pelken, Cristian R?be, Frans Van Valen, Heribert J?rgens & Barbara Dockhorn-Dworniczak. (2001) Establishment of an In Vivo Model for Pediatric Ewing Tumors by Transplantation into NOD/ scid Mice. Pediatric Research 49:3, pages 332-341.
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John D. Whittard & Steven K. Akiyama. (2001) Activation of ?1 Integrins Induces Cell?Cell Adhesion. Experimental Cell Research 263:1, pages 65-76.
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