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Critical Reviews in Biotechnology Volume 29, 2009 - Issue 4
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Review Article

Critical analysis of engineering aspects of shaken flask bioreactors

S. SureshDepartment of Chemical Engineering, Indian Institute of Technology Roorkee, Roorkee-247 667, Uttarakhand, India
,
V.C. SrivastavaDepartment of Chemical Engineering, Indian Institute of Technology Roorkee, Roorkee-247 667, Uttarakhand, IndiaCorrespondence[email protected]/[email protected]
&
I.M. MishraDepartment of Chemical Engineering, Indian Institute of Technology Roorkee, Roorkee-247 667, Uttarakhand, India
Pages 255-278 | Accepted 23 May 2009, Published online: 06 Oct 2009

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Angus Shiue, Shih-Chieh Chen, Jyh-Cheng Jeng, Likuan Zhu & Graham Leggett. (2020) Mixing Performance Analysis of Orbitally Shaken Bioreactors. Applied Sciences 10:16, pages 5597.
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Masato Takahashi & Hideki Aoyagi. (2018) Practices of shake-flask culture and advances in monitoring CO2 and O2. Applied Microbiology and Biotechnology 102:10, pages 4279-4289.
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Zhiming Lu, Kang Wang, Gaofeng Jin, Kang Huang & Jingfeng Huang. (2017) CFD studies on hydrodynamic characteristics of shaking bioreactors with wide conical bottom. Journal of Chemical Technology & Biotechnology 93:3, pages 810-817.
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Astrid Dürauer, Stefanie Hobiger, Cornelia Walther & Alois Jungbauer. (2016) Mixing at the microscale: Power input in shaken microtiter plates. Biotechnology Journal 11:12, pages 1539-1549.
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C. Palacios-Morales, J.P. Aguayo-Vallejo, M.A. Trujillo-Roldán, R. Zenit, G. Ascanio & M.S. Córdova-Aguilar. (2016) The flow inside shaking flasks and its implication for mycelial cultures. Chemical Engineering Science 152, pages 163-171.
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Michael C. FlickingerSuresh Sundaramurthy. 2009. Encyclopedia of Industrial Biotechnology. Encyclopedia of Industrial Biotechnology 1 17 .
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Karen Gómez-Pazarín, Celia Flores, Tania Castillo, Jochen Büchs, Enrique Galindo & Carlos Peña. (2016) Molecular weight and viscosifying power of alginates produced in Azotobacter vinelandii cultures in shake flasks under low power input . Journal of Chemical Technology & Biotechnology 91:5, pages 1485-1492.
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E. Mancilla, C.A. Palacios-Morales, M.S. Córdova-Aguilar, M.A. Trujillo-Roldán, G. Ascanio & R. Zenit. (2015) A hydrodynamic description of the flow behavior in shaken flasks. Biochemical Engineering Journal 99, pages 61-66.
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Xue Xia, Shuangjun Lin, Xiao-Xia Xia, Feng-Song Cong & Jian-Jiang Zhong. (2014) Significance of agitation-induced shear stress on mycelium morphology and lavendamycin production by engineered Streptomyces flocculus. Applied Microbiology and Biotechnology 98:10, pages 4399-4407.
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Márcio B. Machado & Suzanne M. Kresta. (2013) The confined impeller stirred tank (CIST): A bench scale testing device for specification of local mixing conditions required in large scale vessels. Chemical Engineering Research and Design 91:11, pages 2209-2224.
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Patrick Jonczyk, Meike Takenberg, Steffen Hartwig, Sascha Beutel, Ralf G. Berger & Thomas Scheper. (2013) Cultivation of shear stress sensitive microorganisms in disposable bag reactor systems. Journal of Biotechnology 167:4, pages 370-376.
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Mário A.P. Nunes, Pedro C.B. Fernandes & Maria H.L. Ribeiro. (2013) Microtiter plates versus stirred mini-bioreactors in biocatalysis: A scalable approach. Bioresource Technology 136, pages 30-40.
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Chao Li, Jian-Ye Xia, Ju Chu, Yong-Hong Wang, Ying-Ping Zhuang & Si-Liang Zhang. (2013) CFD analysis of the turbulent flow in baffled shake flasks. Biochemical Engineering Journal 70, pages 140-150.
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Alexander Grünberger, Jan van Ooyen, Nicole Paczia, Peter Rohe, Georg Schiendzielorz, Lothar Eggeling, Wolfgang Wiechert, Dietrich Kohlheyer & Stephan Noack. (2013) Beyond growth rate 0.6: Corynebacterium glutamicum cultivated in highly diluted environments . Biotechnology and Bioengineering 110:1, pages 220-228.
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Wolf Klöckner & Jochen Büchs. (2012) Advances in shaking technologies. Trends in Biotechnology 30:6, pages 307-314.
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Takuro Kobayashi & Yu-You Li. (2011) Performance and characterization of a newly developed self-agitated anaerobic reactor with biological desulfurization. Bioresource Technology 102:10, pages 5580-5588.
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Marie‐Françoise Clincke, Emmanuel Guedon, Frances T. Yen, Virginie Ogier, Olivier Roitel & Jean‐Louis Goergen. (2010) Effect of surfactant pluronic F‐68 on CHO cell growth, metabolism, production, and glycosylation of human recombinant IFN‐γ in mild operating conditions. Biotechnology Progress 27:1, pages 181-190.
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