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Chronobiology International
The Journal of Biological and Medical Rhythm Research
Volume 5, 1988 - Issue 4
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Original Article

Time-Dependent Pharmacokinetics and Toxicity of cyclosporine

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Pages 353-362 | Received 01 Jul 1988, Accepted 01 Aug 1988, Published online: 07 Jul 2009

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Read on this site (3)

Marie-France Malmary, Karima Kabbaj, Christian Labat, Raymonde Casse & Jean Oustrin. (1991) Cyclosporine a Dosing-Time-Dependent Effects on Plasma Creatinine and Body Weight in Male Wistar Rats Treated for 3 Weeks. Chronobiology International 8:1, pages 25-34.
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Lane J. Brunner, Kiumars Vadiei, Lalitha V. Iyer & David R. Luke. (1989) Prevention of Cyclosporine-Induced Nephrotoxicity with Pentoxifylline. Renal Failure 11:2-3, pages 97-104.
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Kishor M. Wasan, Lane J. Brunner, Kurt L. Berens, Arthur A. Meltzer & David R. Luke. (1989) Circadian Assessment of Lipids in the Hyperphagic Obese Rat Compared with Lean Litter-Mates. Chronobiology International 6:3, pages 223-228.
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Articles from other publishers (18)

Danyi Lu, Yi Wang, Menglin Chen, Huan Zhao & Dong Dong. 2020. Circadian Pharmacokinetics. Circadian Pharmacokinetics 187 237 .
Lane J Brunner, Joseph T Dipiro & Stuart Feldman. (1994) Metabolic Cage Isolation Reduces Antipyrine Clearance in Rats. Journal of Pharmacy and Pharmacology 46:7, pages 581-584.
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Jinrong Liu & Lane J. Brunner. (2001) Chronic cyclosporine administration induces renal P-glycoprotein in rats. European Journal of Pharmacology 418:1-2, pages 127-132.
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Lane J. Brunner, Ki‐Soo Pai, Myrna Y. Munar, Marc B. Lande, Ali J. Olyaei & Jeanne A. Mowry. (2001) Effect of grapefruit juice on cyclosporin A pharmacokinetics in pediatric renal transplant patients. Pediatric Transplantation 4:4, pages 313-321.
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Lane J. Brunner, William M. Bennett & Dennis R. Koop. (1998) Cyclosporine suppresses rat hepatic cytochrome P450 in a time-dependent manner. Kidney International 54:1, pages 216-223.
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Hitoshi Yamauchi, Eiji Kobayashi, Koh‐ichi Sugimoto, Shuichi Tsuruoka, Machiko Yabana, Masao Ishii & Akio Fujimura. (2007) TIME‐DEPENDENT CYCLOSPORINE A‐INDUCED NEPHROTOXICITY IN RATS. Clinical and Experimental Pharmacology and Physiology 25:6, pages 435-440.
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Liliana E. Albornoz, Susana B. Sanchez, Juan Carlos Bandi, Griselda Canteros, Marcelo De Las Heras & Ricardo C. Mastai. (1997) Pentoxifylline Reduces Nephrotoxicity Associated With Cyclosporine In The Rat By Its Rheological Properties. Transplantation 64:10, pages 1404-1407.
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Ana I Esquifino, Laura Selgas, Valeria Della Maggiore, Patricia O Castrillón & Daniel P Cardinali. (1997) Diurnal changes in cyclosporine effect on ornithine decarboxylase and noradrenergic and cholinergic activities in submaxillary lymph nodes. European Journal of Pharmacology 319:2-3, pages 181-189.
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Akio Fujimura & Akio Ebihara. (1994) Administration time-dependent toxicity of a new immunosuppressive agent, tacrolimus (FK 506). Life Sciences 55:7, pages 485-490.
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Akio Fujimura, Tsuyoshi Shiga, Kyo-ichi Ohashi & Akio Ebihara. (1993) Chronopharmacokinetic Study of a New Immunosuppressive Agent, FK 506, in Mice. Japanese Journal of Pharmacology 61:2, pages 137-139.
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David R. Luke. (2006) Immunosuppressive effect of cyclosporine in the hyperlipidemic rat model. Biopharmaceutics & Drug Disposition 13:9, pages 635-645.
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Kirt J. Vener & Archana Reddy. (1992) Timed treatment of the arthritic diseases: a review and hypothesis. Seminars in Arthritis and Rheumatism 22:2, pages 83-97.
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M. F. Malmary, K. Kabbaj, C. Labat, A. Batalla, I. Houti, S. Moussamih & J. Oustrin. (1992) Chronopharmacokinetics of Cyclosporine A in the Wistar rat following oral administration. European Journal of Drug Metabolism and Pharmacokinetics 17:2, pages 135-144.
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David R. Luke, Lane J. Brunner, Gabriel Lopez-Berestein & Jonathan C. Yau. (1992) Pharmacokinetics of Cyclosporine in Bone Marrow Transplantation: Longitudinal Characterization of Drug in Lipoprotein Fractions. Journal of Pharmaceutical Sciences 81:3, pages 208-211.
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Jonathan C. Yau, Lane J. Brunner, Gabriel Lopez‐Berestein, C. Frederick LeMaistre & David R. Luke. (2012) Therapeutic Drug Monitoring of Cyclosporine‐Lipoprotein Levels. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 11:4, pages 291-295.
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Kurt L. Berens, Kiumars Vadiei, Lane J. Brunner, Kishor M. Wasan & David R. Luke. (1990) Influence of lovastatin on the pharmacokinetics, toxicity and immunologic response of cyclosporine in the obese zucker rat. Biopharmaceutics & Drug Disposition 11:3, pages 197-206.
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David R. Luke, Jeanne E. Beck, Kiumars Vadiei, Mehdi Yousefpour, Charles F. LeMaistre & Jonathan C. Yau. (2013) Longitudinal Study of Cyclosporine and Lipids in Patients Undergoing Bone Marrow Transplantation. The Journal of Clinical Pharmacology 30:2, pages 163-169.
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L. J. Brunner, L. V. Iyer, K. Vadiei, W. V. Weaver & D. R. Luke. (1989) Cyclosporine pharmacokinetics and effect in the Type I diabetic rat model. European Journal of Drug Metabolism and Pharmacokinetics 14:4, pages 287-292.
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