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Endocrine Research Communications Volume 1, 1974 - Issue 1
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Original Article

An Early Cordycepin-Sensitive Event in the Action of Glucocorticoid Hormones on Rat Thymus Cells in vitro: Evidence that Synthesis of Mew Mrna Initiates the Earliest Metabolic Effects of Steroid Hormones

Donald A. Young Department of Medicine and of Radiation Biology and Biophysics, University of Rochester, School of Medicine and Dentistry, Rochester, New York, 14642
,
Thomas Barnard Department of Medicine and of Radiation Biology and Biophysics, University of Rochester, School of Medicine and Dentistry, Rochester, New York, 14642
,
Steven Mendelsohn Department of Medicine and of Radiation Biology and Biophysics, University of Rochester, School of Medicine and Dentistry, Rochester, New York, 14642
&
Stephen Giddings Department of Medicine and of Radiation Biology and Biophysics, University of Rochester, School of Medicine and Dentistry, Rochester, New York, 14642
Pages 63-72 | Received 01 Dec 1973, Published online: 07 Jul 2009

Citations (21)

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Read on this site (1)

Allan Munck, GeraldR. Crabtree & KendallA. Smith. (1978) Effects and receptors of glucocorticoids in rat thymus cells and human peripheral lymphocytes. Journal of Toxicology and Environmental Health 4:2-3, pages 409-425.
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Articles from other publishers (20)

Andrew D. Wallace, Thomas T. Wheeler & Donald A. Young. (1997) Inducibility of E4BP4 Suggests a Novel Mechanism of Negative Gene Regulation by Glucocorticoids. Biochemical and Biophysical Research Communications 232:2, pages 403-406.
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Robert A. Colbert, John M. Amatruda & Donald A. Young. (1985) The hepatic glucocorticoid domain: evidence for early and late hormone-mediated changes in the synthesis of individual protein gene products. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 826:1, pages 49-66.
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E V Maytin, R A Colbert & D A Young. (1985) Early heat shock proteins in primary thymocytes. Evidence for transcriptional and translational regulation.. Journal of Biological Chemistry 260:4, pages 2384-2392.
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Victoria N. Luine & Bruce S. McEwen. 1985. Reproduction. Reproduction 665 721 .
Thomas C. Dembinski & Philip A. Bell. (1984) Glucocorticoids modify the rate of ribosomal RNA synthesis in rat thymus cells by regulating the polymerase elongation rate. Journal of Steroid Biochemistry 21:5, pages 497-504.
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E V Maytin & D A Young. (1983) Separate glucocorticoid, heavy metal, and heat shock domains in thymic lymphocytes.. Journal of Biological Chemistry 258:20, pages 12718-12722.
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Nicholas Thomas, Joshua L. Edwards & Philip A. Bell. (1983) Studies of the mechanism of glucocorticoid-induced pyknosis in isolated rat thymocytes. Journal of Steroid Biochemistry 18:5, pages 519-524.
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John Stevens, Yee-Wan Stevens & Harriette Haubenstock. 1983. Biochemical Actions of Hormones. Biochemical Actions of Hormones 383 446 .
Endo Yoshihiro, Fujihira Eiichi, Araki Tsutomu & Tsurufuji Susumu. (1981) Glucocorticoid receptors in carrageenin-induced granuloma in rats: Activation to dexamethasone-binding form by sulfhydryl compounds. Journal of Steroid Biochemistry 14:12, pages 1337-1345.
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B.P. Voris & D.A. Young. (1981) Glucocorticoid-induced proteins in rat thymus cells.. Journal of Biological Chemistry 256:21, pages 11319-11329.
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D A Young, B P Voris & M L Nicholson. (1981) Cellular and biochemical actions of adrenal glucocorticoid hormones on rat thymic lymphocytes.. Environmental Health Perspectives 38, pages 89-97.
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Lorin K. Johnson, Steven K. Nordeen, James L. Roberts & John D. Baxter. 1980. Gene Regulation by Steroid Hormones. Gene Regulation by Steroid Hormones 153 187 .
D. Duval, F. Homo, C. Fournier & J.P. Dausse. (1979) Glucocorticoid receptors in mouse spleen cell subpopulations. Cellular Immunology 46:1, pages 1-11.
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Philip A. Bell & Neil M. Borthwick. (1979) Regulation of transcription in rat thymus cells by glucocorticoids. Journal of Steroid Biochemistry 11:1, pages 381-387.
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PHILIP A. BELL & NEIL M. BORTHWICK. 1979. Hormonal Steroids. Hormonal Steroids 381 387 .
A. Munck, G. R. Crabtree & K. A. Smith. 1979. Glucocorticoid Hormone Action. Glucocorticoid Hormone Action 341 355 .
JOHN D. BAXTER & ROBERT D. IVARIE. 1978. Receptors and Hormone Action. Receptors and Hormone Action 251 296 .
S K Nordeen & D A Young. (1976) Glucocorticoid action on rat thymic lymphocytes. Experiments utilizing adenosine to support cellular metabolism lead to a reassessment of catabolic hormone actions.. Journal of Biological Chemistry 251:23, pages 7295-7303.
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John A. Cidlowski. (1975) Concanavalin a induced glucocorticoid resistance in rat thymocytes in relation to glucose metabolism and glucocorticoid receptors. Biochemical and Biophysical Research Communications 67:1, pages 463-470.
Crossref
Max H. Cake & Gerald Litwack. 1975. Biochemical Actions of Hormones. Biochemical Actions of Hormones 317 390 .

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