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Annals of Medicine Volume 22, 1990 - Issue 1
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Original Article

The Influence of the Normal Flora on Clostridium difficile Colonisation of the Gut

S. Peter Borriello The Microbial Pathogenicity Research Group, Division of Communicable Diseases, MRC Clinical Research Centre, UK
Pages 61-67 | Received 26 Jun 1989, Published online: 08 Jul 2009

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Giovanny Herrera, Daniel Paredes-Sabja, Manuel Alfonso Patarroyo, Juan David Ramírez & Marina Muñoz. (2021) Updating changes in human gut microbial communities associated with Clostridioides difficile infection. Gut Microbes 13:1.
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Vincent Thomas, Violaine Rochet, Helene Boureau, Caroline Ekstrand, Joel Dore, Anne Collignon & Pierre Bourlioux. (2002) Molecular Characterization and Spatial Analysis of a Simplified Gut Microbiota Displaying Colonization Resistance against Clostridium difficile. Microbial Ecology in Health and Disease 14:4, pages 203-210.
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Kelly R. Reveles, Eric H. Young, Amina R.A.L. Zeidan & Qunfeng Dong. 2021. Handbook of the Biology of Aging. Handbook of the Biology of Aging 367 389 .
Maurício Roberto Motta Pinto da Luz & Ricardo Francisco Waizbort. (2020) Transplantes de microbiota fecal para tratamento da colite pseudomembranosa (1958-2013): prioridade de descoberta e estilos de pensamento na literatura acadêmica. História, Ciências, Saúde-Manguinhos 27:3, pages 859-878.
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Brooke C. Wilson, Tommi Vatanen, Wayne S. Cutfield & Justin M. O'Sullivan. (2019) The Super-Donor Phenomenon in Fecal Microbiota Transplantation. Frontiers in Cellular and Infection Microbiology 9.
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Emily C. Woods, Adrianne N. Edwards, Kevin O. Childress, Joshua B. Jones & Shonna M. McBride. (2018) The C. difficile clnRAB operon initiates adaptations to the host environment in response to LL-37. PLOS Pathogens 14:8, pages e1007153.
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L. Chris Sanchez. 2018. Equine Internal Medicine. Equine Internal Medicine 709 842 .
K Al-Tawil, A Babu, M Loeffler & T Williams. (2017) Second generation cephalosporin antibiotic prophylaxis and Clostridium difficile infection in hip and knee arthroplasty . The Annals of The Royal College of Surgeons of England 99:5, pages 351-354.
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Eva Boon, Conor J. Meehan, Chris Whidden, Dennis H.-J. Wong, Morgan G.I. Langille & Robert G. Beiko. (2014) Interactions in the microbiome: communities of organisms and communities of genes. FEMS Microbiology Reviews 38:1, pages 90-118.
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Cirle A Warren & Richard L Guerrant. (2011) Pathogenic C difficile is here (and everywhere) to stay. The Lancet 377:9759, pages 8-9.
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Mohammad Azam & Richard J. Farrell. 2010. Inflammatory Bowel Disease. Inflammatory Bowel Disease 619 642 .
Gareth C Parkes, Jeremy D Sanderson & Kevin Whelan. (2009) The mechanisms and efficacy of probiotics in the prevention of Clostridium difficile-associated diarrhoea. The Lancet Infectious Diseases 9:4, pages 237-244.
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B. Razavi, A. Apisarnthanarak & L. M. Mundy. (2007) Clostridium difficile: Emergence of Hypervirulence and Fluoroquinolone Resistance. Infection 35:5, pages 300-307.
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Farrin A. Manian, Sangita Aradhyula, Sandy Greisnauer, Diane Senkel, Janice Setzer, Michele Wiechens & P Lynn Meyer. (2007) Is It Clostridium difficile Infection or Something Else? A Case-control Study of 352 Hospitalized Patients With New-onset Diarrhea. Southern Medical Journal 100:8, pages 782-786.
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Michael J. YaegerJoann M. KinyonJ. Glenn Songer. (2016) A Prospective, Case Control Study Evaluating the Association between Clostridium Difficile Toxins in the Colon of Neonatal Swine and Gross and Microscopic Lesions . Journal of Veterinary Diagnostic Investigation 19:1, pages 52-59.
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J. Hughes, N. Taylor, E. Cerda & M.A. de la Cal. 2005. Infection Control in the Intensive Care Unit. Infection Control in the Intensive Care Unit 191 211 .
S. Buyse, E. Azoulay & B. Schlemmer. 2005. Yearbook of Intensive Care and Emergency Medicine 2005. Yearbook of Intensive Care and Emergency Medicine 2005 369 381 .
Richard J. Farrell, Lorraine Kyne & Ciarán P. Kelly. 2005. Inflammatory Bowel Disease: From Bench to Bedside. Inflammatory Bowel Disease: From Bench to Bedside 823 844 .
Reet Mandar, Marika Mikelsaar, Epp Sepp & Heidi Annuk. 2004. Lactic Acid Bacteria. Lactic Acid Bacteria.
Thomas J Borody, Eloise F Warren, Sharyn M Leis, Rosa Surace, Ori Ashman & Steven Siarakas. (2004) Bacteriotherapy Using Fecal Flora. Journal of Clinical Gastroenterology 38:6, pages 475-483.
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John R. Stroehlein. (2004) Treatment of clostridium difficile infection. Current Treatment Options in Gastroenterology 7:3, pages 235-239.
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Samuel L. Jones & Anthony T. Blikslager. 2004. Equine Internal Medicine. Equine Internal Medicine 769 949 .
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I.R. Poxton, J. McCoubrey & G. Blair. (2001) The pathogenicity of Clostridium difficile. Clinical Microbiology and Infection 7:8, pages 421-427.
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Linda S Boeckner, Marilynn I Schnepf & Bryan C Tungland. 2001. 1 63 .
Daniel Allen Nadeau. (2008) Intestinal Warfare: The Role of Short‐Chain Fructooligosaccharides in Health and Disease. Nutrition in Clinical Care 3:5, pages 266-273.
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R. J. Farrell & J. T. LaMont. 2000. Clostridium difficile. Clostridium difficile 109 125 .
Jane Freeman & Mark H Wilcox. (1999) Antibiotics and. Microbes and Infection 1:5, pages 377-384.
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Ciarán P. KellyMDMDJ. Thomas LaMontMDMD. (1998) Clostridium difficile Infection . Annual Review of Medicine 49:1, pages 375-390.
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Gerald W. Tannock. 1997. Gastrointestinal Microbiology. Gastrointestinal Microbiology 187 215 .
Gerald W. Tannock. 1997. Gastrointestinal Microbiology. Gastrointestinal Microbiology 434 465 .
Linda A. Toth & Clark M. Blatteis. 2011. Comprehensive Physiology. Comprehensive Physiology 1489 1519 .
Val H. Smith & Robert D. Holt. (1996) Resource competition and within-host disease dynamics. Trends in Ecology & Evolution 11:9, pages 386-389.
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Christine Roffe. (1996) Biotherapy for antibiotic-associated and other diarrhoeas. Journal of Infection 32:1, pages 1-10.
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Stanislava Stavric & Ervin T. Kornegay. 1995. Biotechnology in Animal Feeds and Animal Feeding. Biotechnology in Animal Feeds and Animal Feeding 205 231 .
Blair A. Jobe, Andrew Grasley, Karen E. Deveney, Clifford W. Deveney & Brett C. Sheppard. (1995) Clostridium difficile colitis: An increasing hospital-acquired illness. The American Journal of Surgery 169:5, pages 480-483.
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Ciaran P. Kelly, Charalabos Pothoulakis & J. Thomas LaMont. (1994) Clostridium difficile Colitis. New England Journal of Medicine 330:4, pages 257-262.
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Charalabos Pothoulakis, Ignazio Castagliuolo, Ciaran P. Kelly & J.Thomas LaMont. (1993) Clostridium difficile-associated diarrhea and colitis: pathogenesis and therapy. International Journal of Antimicrobial Agents 3:1, pages 17-32.
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Val H. Smith. (1993) Resource Competition between Host and Pathogen. BioScience 43:1, pages 21-30.
Crossref
Val H. Smith. 1993. Advances in Microbial Ecology. Advances in Microbial Ecology 1 37 .
Roy FullerDavid J. Hentges. 1992. Probiotics. Probiotics 87 110 .

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