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Annals of Medicine Volume 23, 1991 - Issue 5
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Original Article

Macrophages and Oxidized Low Density Lipoproteins in the Pathogenesis of Atherosclerosis

Seppo Ylä-Herttuala Department of Medicine, University of California, San Diego, California, USA
Pages 561-567 | Published online: 08 Jul 2009

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Hartmut Kuhn. (2005) Biologic relevance of lipoxygenase isoforms in atherogenesis. Expert Review of Cardiovascular Therapy 3:6, pages 1099-1110.
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Karsten A. Hötzer, Carola Henriquez, Eduardo Pino, Soledad Miranda-Rottmann, Augusto Aspillaga, Federico Leighton & Eduardo Lissi. (2005) Antioxidant and pro-oxidant effects of red wine and its fractions on Cu(II) induced LDL oxidation evaluated by absorbance and chemiluminescence measurements. Free Radical Research 39:2, pages 175-183.
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Eduard Gratacós, Elena Casals, Ramón Deulofeu, Olga Gómez, Vicenç Cararach, Pedro L. Alonso & Albert Fortuny. (2001) SERUM ANTIBODIES TO OXIDIZED LOW-DENSITY LIPOPROTEIN IN PREGNANT WOMEN WITH PREECLAMPSIA AND CHRONIC HYPERTENSION: LACK OF CORRELATION WITH LIPID PEROXIDES. Hypertension in Pregnancy 20:2, pages 177-183.
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K. Chen & B. Frei. (1997) The effect of histidine modification on copper-dependent lipid peroxidation in human low-density lipoprotein. Redox Report 3:3, pages 175-181.
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Anita Mlakar, Andreas Batna, Angela Dudda & Gerhard Spiteller. (1996) Iron (II) Ions Induced Oxidation of Ascorbic Acid and Glucose. Free Radical Research 25:6, pages 525-539.
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E. Malle & W. Sattler. (1994) Platelets and the Lipoproteins: Native, Modified and Platelet Modified Lipoproteins. Platelets 5:2, pages 70-83.
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Bernhard Hennig, Michal Toborek, Angelina Alvarado Cader, EricA. Decker & MaryA. Stuart. (1994) Nutrition, endothelial cell metabolism, and atherosclerosis. Critical Reviews in Food Science and Nutrition 34:3, pages 253-282.
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V. Z. Lankin, A. K. Tikhaze, V. Ya. Kosach, G. G. Konovalova & A. V. Kudryashova. (2023) Modification of low-density lipoproteins by low molecular weight carbonyl products of free-radical oxidation of lipids and carbohydrates plays a key role in atherosclerotic lesion of the vascular wall and in endothelial dysfunction. Acta Biomedica Scientifica 8:3, pages 14-24.
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Maria F. Lopes-Virella & Gabriel Virella. 2023. Lipoproteins in Diabetes Mellitus. Lipoproteins in Diabetes Mellitus 339 355 .
Vadim Z. Lankin, Alla K. Tikhaze & Arthur M. Melkumyants. (2022) Dicarbonyl-Dependent Modification of LDL as a Key Factor of Endothelial Dysfunction and Atherosclerotic Vascular Wall Damage. Antioxidants 11:8, pages 1565.
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Maria F. Lopes-Virella & Gabriel Virella. (2019) Modified LDL Immune Complexes and Cardiovascular Disease. Current Medicinal Chemistry 26:9, pages 1680-1692.
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Annas Al-Sharea, Man Kit Sam Lee, Louise E Purton, Edwin D Hawkins & Andrew J Murphy. (2019) The haematopoietic stem cell niche: a new player in cardiovascular disease?. Cardiovascular Research 115:2, pages 277-291.
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Gabriel Virella, Kelsey Wilson, Johnathon Elkes, Samar M. Hammad, Hussein A. Rajab, Yanchun Li, Charlyne Chassereau, Yan Huang & Maria Lopes-Virella. (2018) Immune complexes containing malondialdehyde (MDA) LDL induce apoptosis in human macrophages. Clinical Immunology 187, pages 1-9.
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Brigitte M. Winklhofer-Roob, Gernot Faustmann & Johannes M. Roob. (2017) Low-density lipoprotein oxidation biomarkers in human health and disease and effects of bioactive compounds. Free Radical Biology and Medicine 111, pages 38-86.
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Man K S Lee, Xiao-Lei Moore, Yi Fu, Annas Al-Sharea, Dragana Dragoljevic, Manuel A Fernandez-Rojo, Robert Parton, Dmitri Sviridov, Andrew J Murphy & Jaye P F Chin-Dusting. (2016) High-density lipoprotein inhibits human M1 macrophage polarization through redistribution of caveolin-1. British Journal of Pharmacology 173:4, pages 741-751.
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Maria F. Lopes-Virella & Gabriel Virella. 2014. Lipoproteins in Diabetes Mellitus. Lipoproteins in Diabetes Mellitus 203 213 .
Mitsuhisa Koga, Atsushi Yamauchi, Yuki Kanaoka, Ryusuke Jige, Anna Tsukamoto, Nao Teshima, Tsuyoshi Nishioku & Yasufumi Kataoka. (2013) BMP4 is increased in the aortas of diabetic ApoE knockout mice and enhances uptake of oxidized low density lipoprotein into peritoneal macrophages. Journal of Inflammation 10:1.
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Maria F. Lopes-Virella & Gabriel Virella. (2013) Pathogenic Role of Modified LDL Antibodies and Immune Complexes in Atherosclerosis. Journal of Atherosclerosis and Thrombosis 20:10, pages 743-754.
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M. I. Dushkin. (2012) Macrophage/foam cell is an attribute of inflammation: Mechanisms of formation and functional role. Biochemistry (Moscow) 77:4, pages 327-338.
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I. Missala, U. Kassner & E. Steinhagen-Thiessen. (2012) A Systematic Literature Review of the Association of Lipoprotein(a) and Autoimmune Diseases and Atherosclerosis. International Journal of Rheumatology 2012, pages 1-10.
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Robert Ringseis & Klaus Eder. (2009) Influence of conjugated linoleic acids on functional properties of vascular cells. British Journal of Nutrition 102:8, pages 1099-1116.
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Natasja de BontMihai G. NeteaChantal RoversTineke SmildeAnneke HijmansPierre N.M. DemackerJos W.M. van der MeerAnton F.H. Stalenhoef. (2006) LPS-Induced Release of IL-1 β , IL-1Ra, IL-6, and TNF- α in Whole Blood from Patients with Familial Hypercholesterolemia: No Effect of Cholesterol-Lowering Treatment . Journal of Interferon & Cytokine Research 26:2, pages 101-107.
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Paola Otero, Bartolomé Bonet, Emilio Herrera & Alberto Rabano. (2005) Development of atherosclerosis in the diabetic BALB/c mice. Atherosclerosis 182:2, pages 259-265.
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Laëtitia Pavan, Axelle Hermouet, Vassilis Tsatsaris, Patrice Thérond, Tatsuya Sawamura, Danièle Evain-Brion & Thierry Fournier. (2004) Lipids from Oxidized Low-Density Lipoprotein Modulate Human Trophoblast Invasion: Involvement of Nuclear Liver X Receptors. Endocrinology 145:10, pages 4583-4591.
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