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Original Article

Watermelon extract reduces blood pressure but does not change sympathovagal balance in prehypertensive and hypertensive subjects

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Pages 244-248 | Received 06 Aug 2015, Accepted 30 Jan 2016, Published online: 07 Mar 2016

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Seung Eun Jung,$suffix/text()$suffix/text(), Amy C. Ellis,$suffix/text()$suffix/text() & Kristi Crowe-White,$suffix/text()$suffix/text(). (2018) Intention of Older Women to Consume 100% Watermelon Juice for Vascular Health: An Application of Theory of Planned Behavior. Journal of Nutrition in Gerontology and Geriatrics 37:2, pages 130-143.
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Manoel Miranda Neto, Taís F. da Silva, Fabiano F. de Lima, Thibério M. Q. Siqueira, Lydiane T. Toscano, Stephanney K. M. S. F. de Moura & Alexandre S. Silva. (2017) Whole Red Grape Juice Reduces Blood Pressure at Rest and Increases Post-exercise Hypotension. Journal of the American College of Nutrition 36:7, pages 533-540.
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Amy Cameron Ellis$suffix/text()$suffix/text(), Tanja Dudenbostel$suffix/text()$suffix/text(), Julie L. Locher$suffix/text()$suffix/text() & Kristi Crowe-White$suffix/text()$suffix/text(). (2016) Modulating Oxidative Stress and Inflammation in Elders: The MOXIE Study. Journal of Nutrition in Gerontology and Geriatrics 35:4, pages 219-242.
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Shadia Hamoud Alshahrani, Pushpamala Ramaiah, Ali Sami Dheyab, Mohammad Rudiansyah, Qutaiba A. Qasim, Farag M.A. Altalbawy, Rasha Fadhel Obaid, Abbas F. Almulla, Andrés Alexis Ramírez-Coronel, Gamal A. Gabr, Chairun Nasirin, Yasser Fakri Mustafa & Ali Amin Naghda. (2023) The effect of watermelon supplementation on blood pressure: a meta-analysis of randomised clinical trials. Journal of Herbal Medicine 41, pages 100726.
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Jaikko Daughtry, Caitlin Rasmussen, Martin RosasJr.Jr., Liyue Zhang, Stephanie Lu, Shirin Hooshmand, Changqi Liu, Mark Kern & Mee Young Hong. (2023) Blenderized watermelon consumption decreases body mass index, body mass index percentile, body fat and HbA1c in children with overweight or obesity . Pediatric Obesity 18:8.
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Elmira Karimi, Faezeh Abaj, Mohammad Gholizadeh, Omid Asbaghi, Mohammad Reza Amini, Ehsan Ghaedi & Amir Hadi. (2023) Watermelon consumption decreases risk factors of cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials. Diabetes Research and Clinical Practice 202, pages 110801.
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Hun-Young Park, Sung-Woo Kim, Jisoo Seo, Yanghoon P. Jung, Hyunji Kim, Ah-Jin Kim, Sonwoo Kim & Kiwon Lim. (2023) Dietary Arginine and Citrulline Supplements for Cardiovascular Health and Athletic Performance: A Narrative Review. Nutrients 15:5, pages 1268.
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Rachel Matthews, Kate S. Early, Cullen M. Vincellette, Jack Losso, Guillaume Spielmann, Brian A. Irving & Timothy D. Allerton. (2023) The Effect of Watermelon Juice Supplementation on Heart Rate Variability and Metabolic Response during an Oral Glucose Challenge: A Randomized, Double-Blind, Placebo-Controlled Crossover Trial. Nutrients 15:4, pages 810.
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Sadegh Jafarnejad, Catherine Tsang & Negin Amin. (2022) Potential blood pressure lowering effect of L-citrulline supplementation in at risk populations: a meta-analysis. Nutrition & Food Science 53:1, pages 203-217.
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Mônica Volino-Souza, Gustavo Vieira de Oliveira, Carlos Adam Conte-Junior, Arturo Figueroa & Thiago Silveira Alvares. (2022) Current Evidence of Watermelon (Citrullus lanatus) Ingestion on Vascular Health: A Food Science and Technology Perspective. Nutrients 14:14, pages 2913.
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Adam M. Gonzalez, Anthony G. Pinzone, Shaina E. Lipes, Gerald T. Mangine, Jeremy R. Townsend, Timothy D. Allerton, Katie M. Sell & Jamie J. Ghigiarelli. (2022) Effect of watermelon supplementation on exercise performance, muscle oxygenation, and vessel diameter in resistance-trained men. European Journal of Applied Physiology 122:7, pages 1627-1638.
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Fatima Saqib, Muqeet Wahid, Arwa Abdulkreem AL-Huqail, Hanadi Talal Ahmedah, Nicusor Bigiu, Marius Irimie, Marius Moga, Romina Alina Marc (Vlaic), Oana Lelia Pop & Liana Maria Chicea. (2022) Metabolomics based mechanistic insights to vasorelaxant and cardioprotective effect of ethanolic extract of Citrullus lanatus (Thunb.) Matsum. & Nakai. seeds in isoproterenol induced myocardial infraction. Phytomedicine 100, pages 154069.
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Muqeet Wahid & Fatima Saqib. (2022) Scientific basis for medicinal use of Citrullus lanatus (Thunb.) in diarrhea and asthma: In vitro, in vivo and in silico studies. Phytomedicine 98, pages 153978.
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Salvador J. Jaime, Jessica Nagel, Arun Maharaj, Stephen M. Fischer, Elizabeth Schwab, Christopher Martinson, Kim Radtke, Richard P. Mikat & Arturo Figueroa. (2022) L-Citrulline supplementation attenuates aortic pulse pressure and wave reflection responses to cold stress in older adults. Experimental Gerontology 159, pages 111685.
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Britt Burton-Freeman, Morganne Freeman, Xuhuiqun Zhang, Amandeep Sandhu & Indika Edirisinghe. (2021) Watermelon and l-Citrulline in Cardio-Metabolic Health: Review of the Evidence 2000–2020. Current Atherosclerosis Reports 23:12.
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Francisco A. O. Júnior, Clara R. Ruiz, Yohanna de Oliveira, Marco A. V. Barros, Alexandre S. Silva, Maria S. B. Santos, Vinícius J. B. Martins, Camille M. Balarini & Valdir A. Braga. (2021) Coconut Oil Supplementation Does Not Affect Blood Pressure Variability and Oxidative Stress: A Placebo-Controlled Clinical Study in Stage-1 Hypertensive Patients. Nutrients 13:3, pages 798.
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Cécile Vors, Maryka Rancourt-Bouchard, Charles Couillard, Iris Gigleux, Patrick Couture & Benoît Lamarche. (2021) Sex May Modulate the Effects of Combined Polyphenol Extract and L-citrulline Supplementation on Ambulatory Blood Pressure in Adults with Prehypertension: A Randomized Controlled Trial. Nutrients 13:2, pages 399.
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Audrey C Tierney, Chloe E Rumble, Lauren M Billings & Elena S George. (2020) Effect of Dietary and Supplemental Lycopene on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis. Advances in Nutrition 11:6, pages 1453-1488.
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Mariana Buranelo Egea, Gavin Pierce, Alexandra R Becraft, Marlena Sturm, Wesley Yu & Neil F Shay. (2020) Intake of Watermelon and Watermelon Byproducts in Male Mice Fed a Western-Style Obesogenic Diet Alters Hepatic Gene Expression Patterns, as Determined by RNA Sequencing. Current Developments in Nutrition 4:8, pages nzaa122.
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Jiayi Fan, Eunyoung Park, Liyun Zhang, Indika Edirisinghe, Britt Burton-Freeman & Amandeep K. Sandhu. (2020) Pharmacokinetic Parameters of Watermelon (Rind, Flesh, and Seeds) Bioactive Components in Human Plasma: A Pilot Study to Investigate the Relationship to Endothelial Function. Journal of Agricultural and Food Chemistry 68:28, pages 7393-7403.
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Jahidur Rashid, Shaun S. Kumar, Kathleen M. Job, Xiaoxi Liu, Candice D. Fike & Catherine M. T. Sherwin. (2020) Therapeutic Potential of Citrulline as an Arginine Supplement: A Clinical Pharmacology Review. Pediatric Drugs 22:3, pages 279-293.
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Michael T. Murray. 2020. Textbook of Natural Medicine. Textbook of Natural Medicine 1391 1399.e2 .
Nick E. Flynn, Max H. Shaw & Jace T. Becker. 2020. Amino Acids in Nutrition and Health. Amino Acids in Nutrition and Health 97 109 .
Laura Ellwood, Gizemnur Torun, Zuhal Bahar & Ritin Fernandez. (2019) Effects of flavonoid-rich fruits on hypertension in adults. JBI Database of Systematic Reviews and Implementation Reports 17:10, pages 2075-2105.
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J. Casonatto, J.V. Cavalari, K.F. Goessler, D.G.D. Christofaro, M.D. Polito, D.M. Enokida & K. Grandolfi. (2019) Citrulline malate supplementation might potentiate post-exercise hypotension in hypertensives: A 24-hour analysis. Science & Sports 34:4, pages 261.e1-261.e9.
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Amy C. Ellis, Tanja Dudenbostel & Kristi Crowe-White. (2019) Watermelon Juice: a Novel Functional Food to Increase Circulating Lycopene in Older Adult Women. Plant Foods for Human Nutrition 74:2, pages 200-203.
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Sepideh Mahboobi, Catherine Tsang, Shahla Rezaei & Sadegh Jafarnejad. (2018) RETRACTED ARTICLE: Effect of l-citrulline supplementation on blood pressure: a systematic review and meta-analysis of randomized controlled trials. Journal of Human Hypertension 33:1, pages 10-21.
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Timothy Allerton, David Proctor, Jacqueline Stephens, Tammy Dugas, Guillaume Spielmann & Brian Irving. (2018) l-Citrulline Supplementation: Impact on Cardiometabolic Health. Nutrients 10:7, pages 921.
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Arturo Figueroa, Alexei Wong, Salvador J. Jaime & Joaquin U. Gonzales. (2017) Influence of L-citrulline and watermelon supplementation on vascular function and exercise performance. Current Opinion in Clinical Nutrition & Metabolic Care 20:1, pages 92-98.
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