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Nordic Journal of Psychiatry Volume 70, 2016 - Issue 6
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Research Article

Clozapine treatment and discontinuation in Iceland: A national longitudinal study using electronic patient records

Oddur IngimarssonFaculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland; ;Mental Health Services, Landspitali University Hospital, Reykjavik, Iceland;
,
James H. MacCabeKings College London, UK; ;National Psychosis Unit, Bethlem Royal Hospital, South London and Maudsley NHS Foundation Trust, London, UK
,
Magnús HaraldssonFaculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland; ;Mental Health Services, Landspitali University Hospital, Reykjavik, Iceland;
,
Halldóra JónsdóttirFaculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland; ;Mental Health Services, Landspitali University Hospital, Reykjavik, Iceland;
&
Engilbert SigurdssonFaculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland; ;Mental Health Services, Landspitali University Hospital, Reykjavik, Iceland; Correspondence[email protected]
Pages 450-455 | Received 19 Nov 2015, Accepted 11 Feb 2016, Published online: 06 Apr 2016

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Michelle I. Jakobsen, Julie P. Schaug, Jimmi Nielsen & Erik Simonsen. (2023) Antipsychotic prescribing practices for outpatients with schizophrenia and reasons for non-clozapine treatment - Data from a Danish quality assessment audit. Nordic Journal of Psychiatry 77:5, pages 481-490.
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Edouard-Jules Laforgue, Marion Istvan, Marylène Guerlais, Anicet Chaslerie, Pascal Artarit, Genevieve Vallot, Pascale Jolliet, Marie Grall-Bronnec & Caroline Victorri-Vigneau. (2021) What about regular hematological monitoring during clozapine treatment? A compliance analysis using the French health insurance database. Expert Opinion on Drug Safety 20:10, pages 1247-1256.
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Meha Verma, Sandeep Grover, Subho Chakrabarti & Devakshi Dua. (2021) Attitude towards and experience with clozapine of patients and their caregivers after three months of starting of clozapine. Nordic Journal of Psychiatry 75:5, pages 336-343.
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Wenying Yi, Shenglin She, Jie Zhang, Haibo Wu, Yingjun Zheng & Yuping Ning. (2020) Clozapine Use in Patients with Early-Stage Schizophrenia in a Chinese Psychiatric Hospital. Neuropsychiatric Disease and Treatment 16, pages 2827-2836.
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Oddur Ingimarsson, James H. MacCabe & Engilbert Sigurdsson. (2018) Constipation, ileus and medication use during clozapine treatment in patients with schizophrenia in Iceland. Nordic Journal of Psychiatry 72:7, pages 497-500.
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Oddur Ingimarsson, James H. MacCabe, Magnús Haraldsson, Halldóra Jónsdóttir & Engilbert Sigurdsson. (2017) Risk of diabetes and dyslipidemia during clozapine and other antipsychotic drug treatment of schizophrenia in Iceland. Nordic Journal of Psychiatry 71:7, pages 496-502.
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Articles from other publishers (14)

Ebenezer Oloyede, Olubanke Dzahini, Zadro Abolou, Siobhan Gee, Eromona Whiskey, Diksha Malhotra, Masuma Hussain, Ian Osborne, Cecilia Casetta, Philip McGuire, James H. MacCabe & David Taylor. (2023) Clinical impact of reducing the frequency of clozapine monitoring: controlled mirror-image cohort study. The British Journal of Psychiatry, pages 1-7.
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Ebenezer Oloyede, Eromona Whiskey, Cecilia Casetta, Olubanke Dzahini, Danielle Dunnett, Shreyans Gandhi, Fiona Gaughran, Sukhi Shergill, Philip McGuire, James H MacCabe & David Taylor. (2022) Relaxation of the criteria for entry to the UK Clozapine Central Non-Rechallenge Database: a modelling study. The Lancet Psychiatry 9:8, pages 636-644.
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Graham Blackman, Ebenezer Oloyede, Mark Horowitz, Robert Harland, David Taylor, James MacCabe & Philip McGuire. (2022) Reducing the Risk of Withdrawal Symptoms and Relapse Following Clozapine Discontinuation—Is It Feasible to Develop Evidence-Based Guidelines?. Schizophrenia Bulletin 48:1, pages 176-189.
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Ebenezer Oloyede, Graham Blackman, Eromona Whiskey, Christian Bachmann, Olubanke Dzahini, Sukhi Shergill, David Taylor, Philip McGuire & James MacCabe. (2022) Clozapine haematological monitoring for neutropenia: a global perspective. Epidemiology and Psychiatric Sciences 31.
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Ebenezer Oloyede, Cecilia Casetta, Olubanke Dzahini, Aviv Segev, Fiona Gaughran, Sukhi Shergill, Alek Mijovic, Marinka Helthuis, Eromona Whiskey, James Hunter MacCabe & David Taylor. (2021) There Is Life After the UK Clozapine Central Non-Rechallenge Database. Schizophrenia Bulletin 47:4, pages 1088-1098.
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Katsunori Toyoda, Takeo Hata, Shigeru Yamauchi, Shinya Kinoshita, Masami Nishihara, Kazuhisa Uchiyama, Ken Inada & Tetsufumi Kanazawa. (2021) Clozapine Is Better Tolerated in Younger Patients: Risk Factors for Discontinuation from a Nationwide Database in Japan. Psychiatry Investigation 18:2, pages 101-109.
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Noraly Stam, Heidi Taipale, Antti Tanskanen, Luka Isphording, Cynthia Okhuijsen‐Pfeifer, Catharina C.M. Schuiling‐Veninga, Jens H.J. Bos, Bert J. Bijker, Jari Tiihonen & Jurjen J. Luykx. (2020) Persistence of Antipsychotic Use After Clozapine Discontinuation: A Real‐World Study Across Antipsychotics. Clinical and Translational Science 13:6, pages 1170-1177.
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Jurjen J. Luykx, Noraly Stam, Antti Tanskanen, Jari Tiihonen & Heidi Taipale. (2020) In the aftermath of clozapine discontinuation: comparative effectiveness and safety of antipsychotics in patients with schizophrenia who discontinue clozapine. The British Journal of Psychiatry 217:3, pages 498-505.
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Alp Ucok, Elif Anıl Yağcıoğlu, Mustafa Yıldız, Semra Ulusoy Kaymak, Meram Can Saka, Rümeysa Taşdelen, Ayşen Esen Danacı & Şevin Hun Şenol. (2019) Reasons for clozapine discontinuation in patients with treatment-resistant schizophrenia. Psychiatry Research.
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Marieke M. Beex-Oosterhuis, E.R. (Rob) Heerdink, Arthur R. Van Gool & Rob J. van Marum. (2018) Predicting Unsuccessful Clozapine Treatment After First Use in Adult Patients With Psychotic Disorders. Journal of Clinical Psychopharmacology 38:6, pages 604-608.
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C. J. Bachmann, L. Aagaard, M. Bernardo, L. Brandt, M. Cartabia, A. Clavenna, A. Coma Fusté, K. Furu, K. Garuoliené, F. Hoffmann, S. Hollingworth, K. F. Huybrechts, L. J. Kalverdijk, K. Kawakami, H. Kieler, T. Kinoshita, S. C. López, J. E. Machado‐Alba, M. E. Machado‐Duque, M. Mahesri, P. S. Nishtala, D. Piovani, J. Reutfors, L. K. Saastamoinen, I. Sato, C. C. M. Schuiling‐Veninga, Y.‐C. Shyu, D. Siskind, S. Skurtveit, H. Verdoux, L.‐J. Wang, C. Zara Yahni, H. Zoëga & D. Taylor. (2017) International trends in clozapine use: a study in 17 countries. Acta Psychiatrica Scandinavica 136:1, pages 37-51.
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Caroline Demily, Charlyne Duwime, Alice Poisson, Nathalie Boddaert & Arnold Munnich. (2017) Authors' reply ? Clozapine for mitochondrial psychosis. Molecular Genetics and Metabolism Reports 10, pages 101.
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Hassane Lgaz, Rachid Salghi, Shehdeh Jodeh & Belkheir Hammouti. (2017) Effect of clozapine on inhibition of mild steel corrosion in 1.0 M HCl medium. Journal of Molecular Liquids 225, pages 271-280.
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Oddur Ingimarsson, James H. MacCabe, Magn?s Haraldsson, Halld?ra J?nsd?ttir & Engilbert Sigurdsson. (2016) Neutropenia and agranulocytosis during treatment of schizophrenia with clozapine versus other antipsychotics: an observational study in Iceland. BMC Psychiatry 16:1.
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