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Immunological Investigations
A Journal of Molecular and Cellular Immunology
Volume 44, 2015 - Issue 2
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Original Articles

Peripheral whole blood FOXP3 TSDR methylation: a potential marker in severity assessment of autoimmune diseases and chronic infections

Owen NgalamikaDepartment of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenetics, Changsha, Hunan, PR China, ;Dermatology and Venereology Division, University Teaching Hospital, University of Zambia School of Medicine, Lusaka, Zambia, and
,
Gongping LiangDepartment of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenetics, Changsha, Hunan, PR China,
,
Ming ZhaoDepartment of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenetics, Changsha, Hunan, PR China,
,
Xinhai YuDepartment of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenetics, Changsha, Hunan, PR China,
,
Yang YangDepartment of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenetics, Changsha, Hunan, PR China,
,
Heng YinDepartment of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenetics, Changsha, Hunan, PR China,
,
Yu LiuDepartment of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenetics, Changsha, Hunan, PR China,
,
Susan YungDepartment of Medicine, The University of Hong Kong, Hong Kong, China
,
Tak Mao ChanDepartment of Medicine, The University of Hong Kong, Hong Kong, China
&
Qianjin LuDepartment of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenetics, Changsha, Hunan, PR China, Correspondence[email protected]
 show all
Pages 126-136 | Published online: 01 Aug 2014

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Busra Aydin, Kazim Yalcin Arga & Ayse Serap Karadag. (2020) Omics-Driven Biomarkers of Psoriasis: Recent Insights, Current Challenges, and Future Prospects. Clinical, Cosmetic and Investigational Dermatology 13, pages 611-625.
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Parisa Zafari, Kheirollah Yari, Shayan Mostafaei, Nasrin Iranshahi, Shirin Assar, Adel Fekri & Mahdi Taghadosi. (2018) Analysis of Helios gene expression and Foxp3 TSDR methylation in the newly diagnosed Rheumatoid Arthritis patients. Immunological Investigations 47:6, pages 632-642.
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Hong-Jun Liu, Ai-Fen Zhang, Na Zhao & Xue-Zhong Li. (2016) Role of miR-146a in Enforcing Effect of Specific Immunotherapy on Allergic Rhinitis. Immunological Investigations 45:1, pages 1-10.
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Naoko Kanda, Toshihiko Hoashi & Hidehisa Saeki. (2021) The Defect in Regulatory T Cells in Psoriasis and Therapeutic Approaches. Journal of Clinical Medicine 10:17, pages 3880.
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Chang Zeng, Lam C. Tsoi & Johann E. Gudjonsson. (2021) Dysregulated epigenetic modifications in psoriasis. Experimental Dermatology 30:8, pages 1156-1166.
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Yi-Shu Huang, Wen-Yi Tseng, Felix I. L. Clanchy, Louise M. Topping, Joy Ogbechi, Kay McNamee, Dany Perocheau, Nien-Yi Chiang, Peter Ericsson, Anette Sundstedt, Zhong-Tian Xue, Leif G. Salford, Hans-Olov Sjögren, Trevor W. Stone, Hsi-Hsien Lin, Shue-Fen Luo & Richard O. Williams. (2021) Pharmacological modulation of T cell immunity results in long-term remission of autoimmune arthritis. Proceedings of the National Academy of Sciences 118:19, pages e2100939118.
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Liqiong Zhu, Meilan Liu, Suning Zhang, Yuhua Ou, Ying Chen, Jing Wei, Fang Su, Hui Chen & Jianping Zhang. (2020) Foxp3 TSDR Hypermethylation Is Correlated with Decreased Tregs in Patients with Unexplained Recurrent Spontaneous Abortion. Reproductive Sciences 28:2, pages 470-478.
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Liesa S. Ziegler, Marlene C. Gerner, Ralf L. J. Schmidt, Doris Trapin, Peter Steinberger, Winfried F. Pickl, Christian Sillaber, Gerda Egger, Ilse Schwarzinger & Klaus G. Schmetterer. (2020) Attenuation of canonical NF‐κB signaling maintains function and stability of human Treg. The FEBS Journal 288:2, pages 640-662.
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Ai-Hua Liao & Hong Liu. 2021. Reproductive Immunology. Reproductive Immunology 365 385 .
Christian M. Hedrich. 2021. Systemic Lupus Erythematosus. Systemic Lupus Erythematosus 277 292 .
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Alexey V. Churov, Kylymbek Y. Mamashov & Anastasiia V. Novitskaia. (2020) Homeostasis and the functional roles of CD4+ Treg cells in aging. Immunology Letters 226, pages 83-89.
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Tayfun Hilmi Akbaba, Erdal Sag, Banu Balci-Peynircioglu & Seza Ozen. (2020) Epigenetics for Clinicians from the Perspective of Pediatric Rheumatic Diseases. Current Rheumatology Reports 22:8.
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S. Hanaei, G. Sanati, S. Zoghi, S. Gharibzadeh, V. Ziaee & N. Rezaei. (2020) The status of FOXP3 gene methylation in pediatric systemic lupus erythematosus. Allergologia et Immunopathologia 48:4, pages 332-338.
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Antonio Sahuquillo-Torralba & Blanca de Unamuno-Bustos. (2020) Impacto de la epigenética en el conocimiento de la patogenia y respuesta al tratamiento de la psoriasis. Piel 35:3, pages 176-183.
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Shuai Shao & Johann E. Gudjonsson. 2020. Epigenetics in Allergy and Autoimmunity. Epigenetics in Allergy and Autoimmunity 209 221 .
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Mariela Vega-Cárdenas, Edith E. Uresti-Rivera, Juan D. Cortés-García, Margarita Briones-Espinoza, Víctor M. Ruíz-Rodríguez, Elizabeth Reynaga-Hernández, Alejandro Mendez-Mancilla & Diana P. Portales-Pérez. (2019) Increased levels of adipose tissue-resident Th17 cells in obesity associated with miR-326. Immunology Letters 211, pages 60-67.
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Sarah A. Robertson, Ella S. Green, Alison S. Care, Lachlan M. Moldenhauer, Jelmer R. Prins, M. Louise Hull, Simon C. Barry & Gustaaf Dekker. (2019) Therapeutic Potential of Regulatory T Cells in Preeclampsia—Opportunities and Challenges. Frontiers in Immunology 10.
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Christian Michael Hedrich. 2019. Pharmacoepigenetics. Pharmacoepigenetics 597 608 .
Haijing Wu, Jieyue Liao, Qianwen Li, Ming Yang, Ming Zhao & Qianjin Lu. (2018) Epigenetics as biomarkers in autoimmune diseases. Clinical Immunology 196, pages 34-39.
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Christian Michael Hedrich. (2018) Mechanistic aspects of epigenetic dysregulation in SLE. Clinical Immunology 196, pages 3-11.
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Sarah A. Robertson, Alison S. Care & Lachlan M. Moldenhauer. (2018) Regulatory T cells in embryo implantation and the immune response to pregnancy. Journal of Clinical Investigation 128:10, pages 4224-4235.
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Hulin Ma, Weishi Gao, Xiaoxia Sun & Weixing Wang. (2018) STAT5 and TET2 Cooperate to Regulate FOXP3-TSDR Demethylation in CD4 + T Cells of Patients with Colorectal Cancer . Journal of Immunology Research 2018, pages 1-8.
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Saeed Aslani, Soheila Sobhani, Farhad Gharibdoost, Ahmadreza Jamshidi & Mahdi Mahmoudi. (2018) Epigenetics and pathogenesis of systemic sclerosis; the ins and outs. Human Immunology 79:3, pages 178-187.
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Ye Shu, Qinghua Hu, Hai Long, Christopher Chang, Qianjin Lu & Rong Xiao. (2016) Epigenetic Variability of CD4+CD25+ Tregs Contributes to the Pathogenesis of Autoimmune Diseases. Clinical Reviews in Allergy & Immunology 52:2, pages 260-272.
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