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Immunological Investigations
A Journal of Molecular and Cellular Immunology
Volume 44, 2015 - Issue 2
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Original Articles

Anti-inflammatory Effects of Ethanolic Extract from Sargassum horneri (Turner) C. Agardh on Lipopolysaccharide-Stimulated Macrophage Activation via NF-κB Pathway Regulation

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Read on this site (7)

Rasha Abu-Khudir, Gehan A. Ismail & Thoria Diab. (2021) Antimicrobial, Antioxidant, and Anti-Tumor Activities of Sargassum linearifolium and Cystoseira crinita from Egyptian Mediterranean Coast. Nutrition and Cancer 73:5, pages 829-844.
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Kalahe Hewage Iresha Nadeeka Madushani Herath, Jinhee Cho, Hyo Jin Kim, Duong Thi Thuy Dinh, Hyun-Soo Kim, Ginnae Ahn, You-Jin Jeon & Youngheun Jee. (2021) Polyphenol containing Sargassum horneri attenuated Th2 differentiation in splenocytes of ovalbumin-sensitised mice: involvement of the transcription factors GATA3/STAT5/NLRP3 in Th2 polarization. Pharmaceutical Biology 59:1, pages 1462-1470.
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. (2017) Letter from the Editor 2017. Immunological Investigations 46:8, pages 759-764.
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Rohit Kumar, Yogendra Kumar Gupta, Surender Singh & Amol Patil. (2016) Glorisa superba Hydroalcoholic Extract from Tubers Attenuates Experimental Arthritis by Downregulating Inflammatory Mediators, and Phosphorylation of ERK/JNK/p-38. Immunological Investigations 45:7, pages 603-618.
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Rohit Kumar, Vinod Nair, Yogendra Kumar Gupta, Surender Singh & S. Arunraja. (2016) Berberis aristata Ameliorates Adjuvant-Induced Arthritis by Inhibition of NF-κB and Activating Nuclear Factor-E2-related Factor 2/hem Oxygenase (HO)-1 Signaling Pathway. Immunological Investigations 45:6, pages 473-489.
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Sungeun Ahn, Muhammad Hanif Siddiqi, Veronica Castro Aceituno, Shakina Yesmin Simu & Deok Chun Yang. (2016) Suppression of MAPKs/NF-κB Activation Induces Intestinal Anti-Inflammatory Action of Ginsenoside Rf in HT-29 and RAW264.7 Cells. Immunological Investigations 45:5, pages 439-449.
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Huabing Tan, Qin He, Rugui Li, Feifei Lei & Xu Lei. (2016) Trillin Reduces Liver Chronic Inflammation and Fibrosis in Carbon Tetrachloride (CCl4) Induced Liver Injury in Mice. Immunological Investigations 45:5, pages 371-382.
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Articles from other publishers (34)

Su-Bin Park, Woo Kwon Jung, Hwa Young Yu & Junghyun Kim. (2023) The Effects of Sargassum horneri Extract and Fucoidan on Tear Hyposecretion and Ocular Surface Injury in Rats with Dry Eye Diseases. Current Issues in Molecular Biology 45:8, pages 6583-6592.
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Sally M. Khadrawy, Doaa Sh. Mohamed, Randa M. Hassan, Mohamed A. Abdelgawad, Mohammed M. Ghoneim, Sultan Alshehri & Nema S. Shaban. (2023) Royal Jelly and Chlorella vulgaris Mitigate Gibberellic Acid-Induced Cytogenotoxicity and Hepatotoxicity in Rats via Modulation of the PPARα/AP-1 Signaling Pathway and Suppression of Oxidative Stress and Inflammation. Foods 12:6, pages 1223.
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Belgheis Ebrahimi, Saeid Baroutian, Jinyao Li, Baohong Zhang, Tianlei Ying & Jun Lu. (2023) Combination of marine bioactive compounds and extracts for the prevention and treatment of chronic diseases. Frontiers in Nutrition 9.
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Jun Hwi Cho, Dae Hyun Kim, Jong Suk Lee, Mi-Suk Seo, Mi Eun Kim & Jun Sik Lee. (2022) Sargassum horneri (Turner) C. Agardh Extract Regulates Neuroinflammation In Vitro and In Vivo. Current Issues in Molecular Biology 44:11, pages 5416-5426.
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Na Zhou, Na Wu, Yao Yao, Shuping Chen, Mingsheng Xu, Zhongping Yin, Yan Zhao & Yonggang Tu. (2022) Anti-inflammatory effects of tripeptide WLS on TNF-α-induced HT-29 cells and DSS-induced colitis in mice. Food & Function 13:18, pages 9496-9512.
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Tharuka Gunathilake, Taiwo O. Akanbi, Hafiz A. R. Suleria, Tim D. Nalder, David S. Francis & Colin J. Barrow. (2022) Seaweed Phenolics as Natural Antioxidants, Aquafeed Additives, Veterinary Treatments and Cross-Linkers for Microencapsulation. Marine Drugs 20:7, pages 445.
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Eun-Ji Joung, Lei Cao, Wi-Gyeong Gwon, Mi-Sung Kwon, Kwon Taek Lim & Hyeung-Rak Kim. (2022) Meroterpenoid-Rich Ethanoic Extract of Sargassum macrocarpum Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice. Foods 11:3, pages 329.
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Cristina Mihaela Ghiciuc, Andrei Gheorghe Vicovan, Celina Silvia Stafie, Sabina Antonela Antoniu & Paraschiva Postolache. (2021) Marine-Derived Compounds for the Potential Treatment of Glucocorticoid Resistance in Severe Asthma. Marine Drugs 19:11, pages 586.
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Maki Morita, Shinobu Sugihara, Yumiko Inoue, Yoshiko Suyama, Tomomi Notsu, Yasutaka Yamamoto, Hiromi Sakaguchi, Kohei Fukuoka, Yusuke Endo, Atsuro Koga, Hitoshi KawamotoMinoru FunakoshiYasunari MikiShunjiro Yagi, Haruaki Ninomiya & Ichiro Hisatome. (2021) Angiogenic effects of high molecular weight fucoidan in a mouse ischemic limb model. Vascular Failure 4:2, pages 61-67.
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Marcelo D. Catarino, Sónia J. Amarante, Nuno Mateus, Artur M. S. Silva & Susana M. Cardoso. (2021) Brown Algae Phlorotannins: A Marine Alternative to Break the Oxidative Stress, Inflammation and Cancer Network. Foods 10:7, pages 1478.
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Wonmin Ko, Hwan Lee, Nayeon Kim, Hee Geun Jo, Eun-Rhan Woo, Kyounghoon Lee, Young Seok Han, Sang Rul Park, Ginnae Ahn, Sun Hee Cheong & Dong-Sung Lee. (2021) The Anti-Oxidative and Anti-Neuroinflammatory Effects of Sargassum horneri by Heme Oxygenase-1 Induction in BV2 and HT22 Cells. Antioxidants 10:6, pages 859.
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Zeynab Kohandel, Tahereh Farkhondeh, Michael Aschner & Saeed Samarghandian. (2021) Nrf2 a molecular therapeutic target for Astaxanthin. Biomedicine & Pharmacotherapy 137, pages 111374.
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Shigeru Murakami, Chihiro Hirazawa, Takuma Ohya, Rina Yoshikawa, Toshiki Mizutani, Ning Ma, Mitsuru Moriyama, Takashi Ito & Chiaki Matsuzaki. (2021) The Edible Brown Seaweed Sargassum horneri (Turner) C. Agardh Ameliorates High-Fat Diet-Induced Obesity, Diabetes, and Hepatic Steatosis in Mice. Nutrients 13:2, pages 551.
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Eui Jeong Han, Hyun-Soo Kim, Kyungsook Jung, Kalu Kapuge Asanka Sanjeewa, Kalahe Hewage Iresha Nadeeka Madushani Herath, WonWoo Lee, Youngheun Jee, You-Jin Jeon, Jeongjun Lee, Taehee Kim, Ilekuttige Priyan Shanura Fernando & Ginnae Ahn. (2021) Sargassum horneri ethanol extract ameliorates TNF-α/IFN-γ-induced inflammation in human keratinocytes and TPA-induced ear edema in mice. Food Bioscience 39, pages 100831.
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Marcelo D. Catarino, Ana Silva, Maria T. Cruz, Nuno Mateus, Artur M.S. Silva & Susana M. Cardoso. (2020) Phlorotannins from Fucus vesiculosus: Modulation of Inflammatory Response by Blocking NF-κB Signaling Pathway. International Journal of Molecular Sciences 21:18, pages 6897.
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Md. Abdul Hannan, Raju Dash, Md. Nazmul Haque, Md. Mohibbullah, Abdullah Al Mamun Sohag, Md. Ataur Rahman, Md Jamal Uddin, Mahboob Alam & Il Soo Moon. (2020) Neuroprotective Potentials of Marine Algae and Their Bioactive Metabolites: Pharmacological Insights and Therapeutic Advances. Marine Drugs 18:7, pages 347.
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Mohammed I. Rushdi, Iman A. M. Abdel-Rahman, Hani Saber, Eman Zekry Attia, Wedad M. Abdelraheem, Hashem A. Madkour, Hossam M. Hassan, Abeer H. Elmaidomy & Usama Ramadan Abdelmohsen. (2020) Pharmacological and natural products diversity of the brown algae genus Sargassum . RSC Advances 10:42, pages 24951-24972.
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Menglu Xia, Chunping Liu, Lei Gao & Yanbin Lu. (2019) One-Step Preparative Separation of Phytosterols from Edible Brown Seaweed Sargassum horneri by High-Speed Countercurrent Chromatography. Marine Drugs 17:12, pages 691.
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Saraswati, Puspo Edi Giriwono, Diah Iskandriati, Chin Ping Tan & Nuri Andarwulan. (2019) Sargassum Seaweed as a Source of Anti-Inflammatory Substances and the Potential Insight of the Tropical Species: A Review. Marine Drugs 17:10, pages 590.
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Claudia Juárez-Portilla, Tatiana Olivares-Bañuelos, Tania Molina-Jiménez, José Armando Sánchez-Salcedo, Diana I. Del Moral, Thuluz Meza-Menchaca, Mónica Flores-Muñoz, Óscar López-Franco, Gabriel Roldán-Roldán, Arturo Ortega & Rossana C. Zepeda. (2019) Seaweeds-derived compounds modulating effects on signal transduction pathways: A systematic review. Phytomedicine 63, pages 153016.
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Thilina U. Jayawardena, Hyun-Soo Kim, K.K. Asanka Sanjeewa, Seo-Young Kim, Jung-Rae Rho, Youngheun Jee, Ginnae Ahn & You-Jin Jeon. (2019) Sargassum horneri and isolated 6-hydroxy-4,4,7a-trimethyl-5,6,7,7a-tetrahydrobenzofuran-2(4H)-one (HTT); LPS-induced inflammation attenuation via suppressing NF-κB, MAPK and oxidative stress through Nrf2/HO-1 pathways in RAW 264.7 macrophages. Algal Research 40, pages 101513.
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K. K. Asanka Sanjeewa, I. P. S. Fernando, Seo-Young Kim, Won-Suck Kim, Ginnae Ahn, Youngheun Jee & You-Jin Jeon. (2019) Ecklonia cava (Laminariales) and Sargassum horneri (Fucales) synergistically inhibit the lipopolysaccharide-induced inflammation via blocking NF-κB and MAPK pathways. ALGAE 34:1, pages 45-56.
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Kalahe Hewage Iresha Nadeeka Madushani Herath, Jinhee Cho, Areum Kim, Hyun-Soo Kim, Eui Jeong Han, Hak Ju Kim, Myung Sook Kim, Ginnae Ahn, You-Jin Jeon & Youngheun Jee. (2019) Differential modulation of immune response and cytokine profiles of Sargassum horneri ethanol extract in murine spleen with or without Concanavalin A stimulation. Biomedicine & Pharmacotherapy 110, pages 930-942.
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Thilina U. Jayawardena, K. K. Asanka Sanjeewa, I. P. Shanura Fernando, Bo Mi Ryu, Min-Cheol Kang, Youngheun Jee, Won Woo Lee & You-Jin Jeon. (2018) Sargassum horneri (Turner) C. Agardh ethanol extract inhibits the fine dust inflammation response via activating Nrf2/HO-1 signaling in RAW 264.7 cells. BMC Complementary and Alternative Medicine 18:1.
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Callie Farruggia, Mi-Bo Kim, Minkyung Bae, Yoojin Lee, Tho X. Pham, Yue Yang, Myung Joo Han, Young-Ki Park & Ji-Young Lee. (2018) Astaxanthin exerts anti-inflammatory and antioxidant effects in macrophages in NRF2-dependent and independent manners. The Journal of Nutritional Biochemistry 62, pages 202-209.
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Patrícia Máximo, Luísa Ferreira, Paula Branco, Pedro Lima & Ana Lourenço. (2018) Secondary Metabolites and Biological Activity of Invasive Macroalgae of Southern Europe. Marine Drugs 16:8, pages 265.
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Jin-Hye Lee, Yun-Kyung Lee, Yu-Ra Choi, Joon Park, Sung Keun Jung & Yoon Hyuk Chang. (2018) The characterization, selenylation and anti-inflammatory activity of pectic polysaccharides extracted from Ulmus pumila L.. International Journal of Biological Macromolecules 111, pages 311-318.
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Dong-Sub Kim, Nak-Yun Sung, Sang-Yun Park, Geon Kim, Ji Eom, Jin-Gon Yoo, In-Ra Seo, In-Jun Han, Young-Baik Cho & Kyung-Ah Kim. (2018) Immunomodulating activity of Sargassum horneri extracts in RAW264.7 macrophages . Journal of Nutrition and Health 51:6, pages 507.
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Shahin Roohinejad, Mohamed Koubaa, Francisco J. Barba, Sania Saljoughian, Mehrnoush Amid & Ralf Greiner. (2017) Application of seaweeds to develop new food products with enhanced shelf-life, quality and health-related beneficial properties. Food Research International 99, pages 1066-1083.
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Eun-Ji Joung, Wi-Gyeong Gwon, Taisun Shin, Bok-Mi Jung, JaeSue Choi & Hyeung-Rak Kim. (2016) Anti-inflammatory action of the ethanolic extract from Sargassum serratifolium on lipopolysaccharide-stimulated mouse peritoneal macrophages and identification of active components. Journal of Applied Phycology 29:1, pages 563-573.
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Shamim Ahmad. 2016. Reactive Oxygen Species in Biology and Human Health. Reactive Oxygen Species in Biology and Human Health 25 40 .
Li Ma, Chuan-an Shen, Lei Gao, Da-wei Li, Yu-ru Shang, Kai Yin, Dong-xu Zhao, Wen-feng Cheng & Dong-qin Quan. (2016) Anti-inflammatory activity of chitosan nanoparticles carrying NF-κB/p65 antisense oligonucleotide in RAW264.7 macropghage stimulated by lipopolysaccharide. Colloids and Surfaces B: Biointerfaces 142, pages 297-306.
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Xianjun Yu, Qun Zhao, Haiwei Zhang, Cunxian Fan, Xixi Zhang, Qun Xie, Chengxian Xu, Yongbo Liu, Xiaoxia Wu, Quanbin Han & Haibing Zhang. (2016) Gambogenic acid inhibits LPS-simulated inflammatory response by suppressing NF-κB and MAPK in macrophages. Acta Biochimica et Biophysica Sinica 48:5, pages 454-461.
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Wen-Juan Du, Xiao-Lin Yang, Zi-Jing Song, Jiao-Ying Wang, Wen-Jun Zhang, Xin He, Run-Qi Zhang, Chun-Feng Zhang, Fei Li, Chun-Hao Yu, Chong-Zhi Wang & Chun-Su Yuan. (2016) Antitumor Activity of Total Flavonoids from Daphne genkwa in Colorectal Cancer. Phytotherapy Research 30:2, pages 323-330.
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