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Immunological Investigations
A Journal of Molecular and Cellular Immunology
Volume 44, 2015 - Issue 4
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Original Articles

Significant Impact of IL-6 -174G/C but Inverse Relation with -634 C/G Polymorphism in Patients with Non-Small Cell Lung Cancer in Kashmiri Population

Imtiyaz A. BhatDepartment of Immunology and Molecular Medicine, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, India,
,
Iqbal QasimDepartment of Immunology and Molecular Medicine, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, India,
,
Khalid Z. MasoodiDivision of Biotechnology, SKUAST Kashmir, Shalimar, Srinagar, India,
,
Shabeer A. PaulDepartment of General Medicine, Sher-i-Kashmir Institute of Medical Sciences, Medical College, Bemina, Srinagar, India,
,
Bashir A. BhatDepartment of Plastic Surgery, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, India, and
,
Roohi RasoolDepartment of Immunology and Molecular Medicine, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, India,
,
S. A. AzizDepartment of Medical Oncology, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, India
&
Zafar A. ShahDepartment of Immunology and Molecular Medicine, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, India, Correspondence[email protected] [email protected]
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Pages 349-360 | Published online: 05 May 2015

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Kaiyue Ding, Minhan Yi, Linsen Li & Yuan Zhang. (2021) Interleukin polymorphisms and protein levels associated with lung cancer susceptibility and phenotypes. Expert Review of Clinical Immunology 17:9, pages 1029-1040.
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Ya Cao, Haitao Huang, Zhenxin Wang & Guangbo Zhang. (2017) The Inflammatory CXC Chemokines, GROαhigh, IP-10low, and MIGlow, in Tumor Microenvironment Can Be Used as New Indicators for Non-small Cell Lung Cancer Progression. Immunological Investigations 46:4, pages 361-374.
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Articles from other publishers (12)

Paulina Wigner-Jeziorska, Radosław Grębowski, Joanna Saluk, Michał Bijak & Janusz Szemraj. (2023) Polymorphic variations and mRNA expression of the genes encoding interleukins as well as enzymes of oxidative and nitrative stresses as a potential risk of nephrolithiasis development. PLOS ONE 18:10, pages e0293280.
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Xun Wang, Yikui Hu, Peng Zhang & Chunlian Tang. (2022) To investigation of the correlation between serum IL-6, IL-8, and TNF-a levels and Helicobacter pylori infection in gastric cancer patients based on drug-loaded magnetic nanoparticles. Applied Nanoscience 13:5, pages 3459-3464.
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Radosław Grębowski, Joanna Saluk, Michał Bijak, Janusz Szemraj & Paulina Wigner. (2023) Variability, Expression, and Methylation of IL-6 and IL-8 Genes in Bladder Cancer Pathophysiology. International Journal of Molecular Sciences 24:7, pages 6266.
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Romério Alencar de Oliveira Filho, José Gildo de Moura Monteiro Júnior, Dário Celestino Sobral Filho, Dilênia de Oliveira Cipriano Torres, Fabrício Oliveira Souto, Danyelly Bruneska Gondim Martins, José Luiz de Lima Filho & Rosângela Ferreira Frade de Araújo. (2020) Impact of cytokines levels and interleukin 6 (-634 C>G) polymorphism on clinical outcomes in patients with sepsis. Meta Gene 26, pages 100814.
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Xiaoping Wei, Chen Wang, Haiming Feng, Bing Li, Peng Jiang, Jianbao Yang, Duojie Zhu, Shaobo Zhang, Tao Jin & Yuqi Meng. (2020) Effects of ALOX5, IL6R and SFTPD gene polymorphisms on the risk of lung cancer: A case-control study in China. International Immunopharmacology 79, pages 106155.
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Houda Kaanane, Nezha Senhaji, Hind Berradi, Nadia Benchakroun, Abdellatif Benider, Mehdi Karkouri, Hicham El Attar, IGOT CASA, Meriem Khyatti & Sellama Nadifi. (2019) Association of Variants in IL6-Related Genes with Lung Cancer Risk in Moroccan Population. Lung 197:5, pages 601-608.
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Linghui Zhou, Yi Zheng, Tian Tian, Kang Liu, Meng Wang, Shuai Lin, Yujiao Deng, Cong Dai, Peng Xu, Qian Hao, Huafeng Kang & Zhijun Dai. (2018) Associations of interleukin-6 gene polymorphisms with cancer risk: Evidence based on 49,408 cancer cases and 61,790 controls. Gene 670, pages 136-147.
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Cristina Pérez-Ramírez, Ahmed Alnatsha, Marisa Cañadas-Garre, Eduardo Villar, Javier Valdivia-Bautista, María J. Faus-Dáder & Miguel Á. Calleja-Hernández. (2017) Cytokine single-nucleotide polymorphisms and risk of non-small-cell lung cancer. Pharmacogenetics and Genomics 27:12, pages 438-444.
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Cristina Pérez-Ramírez, Marisa Cañadas-Garre, Ahmed Alnatsha, Miguel Ángel Molina, Ana I. Robles, Eduardo Villar, Juan Ramón Delgado, María José Faus-Dáder & Miguel Ángel Calleja-Hernández. (2017) Interleukins as new prognostic genetic biomarkers in non-small cell lung cancer. Surgical Oncology 26:3, pages 278-285.
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Tong-Zu Liu, Zhong-Qiang Guo, Ting Wang, Yue Cao, Di Huang & Xing-Huan Wang. (2017) Meta-analysis of the role of IL-6 rs1800795 polymorphism in the susceptibility to prostate cancer. Medicine 96:11, pages e6126.
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Ayse Feyda NursalMustafa PehlivanHandan Haydaroğlu SahinSacide Pehlivan. (2016) The Associations of IL-6, IFN-γ, TNF-α, IL-10, and TGF-β1 Functional Variants with Acute Myeloid Leukemia in Turkish Patients . Genetic Testing and Molecular Biomarkers 20:9, pages 544-551.
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Soo Ok Lee, Xiaodong Yang, Shanzhou Duan, Ying Tsai, Laura R. Strojny, Peter Keng & Yuhchyau Chen. (2015) IL-6 promotes growth and epithelial-mesenchymal transition of CD133+ cells of non-small cell lung cancer. Oncotarget 7:6, pages 6626-6638.
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