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Seminars in Ophthalmology Volume 28, 2013 - Issue 5-6: Genetic Advances in Ophthalmology
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Research Article

Fuchs Endothelial Cornea Dystrophy: A Review of the Genetics Behind Disease Development

Cecily E. HamillMassachusetts Eye and Ear Infirmary Boston, MassachusettsUSACorrespondence[email protected]
,
Thore SchmedtMassachusetts Eye and Ear Infirmary Boston, MassachusettsUSA
&
Ula JurkunasMassachusetts Eye and Ear Infirmary Boston, MassachusettsUSA
Pages 281-286 | Received 30 Apr 2013, Accepted 11 Jul 2013, Published online: 18 Oct 2013

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Stephan Ong Tone & Ula Jurkunas. (2019) Imaging the Corneal Endothelium in Fuchs Corneal Endothelial Dystrophy. Seminars in Ophthalmology 34:4, pages 340-346.
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Ester Fernández López, Fook Chang Lam, Marieke Bruinsma, Lamis Baydoun, Isabel Dapena & Gerrit RJ Melles. (2015) Fuchs endothelial corneal dystrophy: current treatment recommendations and experimental surgical options. Expert Review of Ophthalmology 10:3, pages 301-312.
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Articles from other publishers (33)

Rohan Bir Singh, Uday Pratap Singh ParmarFrancesca KahaleBennie H. Jeng & Vishal Jhanji. (2023) Prevalence and Economic Burden of Fuchs Endothelial Corneal Dystrophy in the Medicare Population in the United States. Cornea.
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Pietro ViolaEnrico NeriValeria TestaMohit Parekh, Roberto CianAndrea Grassetto & Vito Romano. (2023) Clinical Outcomes of Preloaded Descemet Membrane Endothelial Keratoplasty With Endothelium Inward: A 24-Month Comparative Analysis Between Fuchs Endothelial Corneal Dystrophy and Bullous Keratopathy. Cornea 42:9, pages 1133-1139.
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Subhradeep Sarkar, Priyalakshmi Panikker, Sharon D’Souza, Rohit Shetty, Rajiv R. Mohan & Arkasubhra Ghosh. (2023) Corneal Regeneration Using Gene Therapy Approaches. Cells 12:9, pages 1280.
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Rajalakshmy Ayilam Ramachandran, Jose Marcos Sanches & Danielle M. Robertson. (2023) The roles of autophagy and mitophagy in corneal pathology: current knowledge and future perspectives. Frontiers in Medicine 10.
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Spela Stunf Pukl. (2022) MicroRNA of Epithelial to Mesenchymal Transition in Fuchs’ Endothelial Corneal Dystrophy. Genes 13:10, pages 1711.
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Yuh-Shin Chang, Chung-Han Ho, Jhi-Joung Wang, Sung-Huei Tseng & Ren-Long Jan. (2022) The Sociodemographic and Risk Factors for Fuchs’ Endothelial Dystrophy: A Nationwide, Matched Case–Control Study in Taiwan. Journal of Personalized Medicine 12:2, pages 305.
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Anupama ChalimeswamyMarasarakottige Yogananda ThanujaSudhir H. Ranganath, Kaveet PandyaUday B. KompellaSangly P. Srinivas. (2022) Oxidative Stress Induces a Breakdown of the Cytoskeleton and Tight Junctions of the Corneal Endothelial Cells. Journal of Ocular Pharmacology and Therapeutics 38:1, pages 74-84.
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Glenn C. Cockerham, Kenneth R. Kenyon & Peter S. Hersh. 2022. Albert and Jakobiec's Principles and Practice of Ophthalmology. Albert and Jakobiec's Principles and Practice of Ophthalmology 555 643 .
Jessica N. Cooke Bailey, Lucia Sobrin & Janey L. Wiggs. 2022. Albert and Jakobiec's Principles and Practice of Ophthalmology. Albert and Jakobiec's Principles and Practice of Ophthalmology 2911 2932 .
Xuerui Liu, Tao Zheng, Chuchu Zhao, Yi Zhang, Hanruo Liu, Liyuan Wang & Ping Liu. (2021) Genetic mutations and molecular mechanisms of Fuchs endothelial corneal dystrophy. Eye and Vision 8:1.
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Amr Elsawy, Taher Eleiwa, Collin Chase, Eyup Ozcan, Mohamed Tolba, William Feuer, Mohamed Abdel-Mottaleb & Mohamed Abou Shousha. (2021) Multidisease Deep Learning Neural Network for the Diagnosis of Corneal Diseases. American Journal of Ophthalmology 226, pages 252-261.
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Isabelle Xu, Mathieu Thériault, Isabelle Brunette, Patrick J. Rochette & Stéphanie Proulx. (2021) Matrix metalloproteinases and their inhibitors in Fuchs endothelial corneal dystrophy. Experimental Eye Research 205, pages 108500.
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Stephan Ong Tone, Viridiana Kocaba, Myriam Böhm, Adam Wylegala, Tomas L. White & Ula V. Jurkunas. (2021) Fuchs endothelial corneal dystrophy: The vicious cycle of Fuchs pathogenesis. Progress in Retinal and Eye Research 80, pages 100863.
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Glenn C. Cockerham, Kenneth R. Kenyon & Peter S. Hersh. 2020. Albert and Jakobiec's Principles and Practice of Ophthalmology. Albert and Jakobiec's Principles and Practice of Ophthalmology 1 89 .
Jessica N. Cooke Bailey, Lucia Sobrin & Janey L. Wiggs. 2020. Albert and Jakobiec's Principles and Practice of Ophthalmology. Albert and Jakobiec's Principles and Practice of Ophthalmology 1 22 .
Yuichi Tokuda, Naoki Okumura, Yuya Komori, Naoya Hanada, Kei Tashiro, Noriko Koizumi & Masakazu Nakano. (2020) Transcriptome dataset of human corneal endothelium based on ribosomal RNA-depleted RNA-Seq data. Scientific Data 7:1.
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Eric Chen, Kelley Bohm, Mark Rosenblatt & Kai Kang. (2020) Epigenetic regulation of anterior segment diseases and potential therapeutics. The Ocular Surface 18:3, pages 383-395.
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Myron Yanoff & Joseph W. Sassani. 2020. Ocular Pathology. Ocular Pathology 272 356.e7 .
Robert P. IgoJr.Jr. & Jessica N. Cooke Bailey. 2020. Genetics and Genomics of Eye Disease. Genetics and Genomics of Eye Disease 259 275 .
Stephan Ong Tone, Matthew James Bruha, Myriam Böhm, Christina Prescott & Ula Jurkunas. (2019) Regional variability in corneal endothelial cell density between guttae and non-guttae areas in Fuchs endothelial corneal dystrophy. Canadian Journal of Ophthalmology 54:5, pages 570-576.
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Shruti Aggarwal, Bernardo M. Cavalcanti, Laura Regali, Andrea Cruzat, Monique Trinidad, Candice Williams, Ula V. Jurkunas & Pedram Hamrah. (2018) In Vivo Confocal Microscopy Shows Alterations in Nerve Density and Dendritiform Cell Density in Fuchs’ Endothelial Corneal Dystrophy. American Journal of Ophthalmology 196, pages 136-144.
Crossref
Esam T. Ahmed Mohamed, Jean-Marc Perone, Sebastian Brand, Michael Koegel & Nico F. Declercq. (2018) Scanning Acoustic Microscopy Comparison of Descemet's Membrane Normal Tissue and Tissue With Fuchs' Endothelial Dystrophy. Investigative Opthalmology & Visual Science 59:13, pages 5627.
Crossref
Takashi Miyai. (2018) Fuchs Endothelial Corneal Dystrophy and Mitochondria. Cornea 37:1, pages S74-S77.
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Michael D. Wagoner, Laura R. Bohrer, Benjamin T. Aldrich, Mark A. Greiner, Robert F. Mullins, Kristan S. Worthington, Budd A. Tucker & Luke A. Wiley. (2018) Feeder-free differentiation of cells exhibiting characteristics of corneal endothelium from human induced pluripotent stem cells. Biology Open.
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Abraham Kuot, Alex W. Hewitt, Grant R. Snibson, Emmanuelle Souzeau, Richard Mills, Jamie E. Craig, Kathryn P. Burdon & Shiwani Sharma. (2017) TGC repeat expansion in the TCF4 gene increases the risk of Fuchs’ endothelial corneal dystrophy in Australian cases. PLOS ONE 12:8, pages e0183719.
Crossref
José Augusto Urrego-Díaz, Juan Sebastián Frías-Ordoñez, Germán Figueroa-Echandía & Guillermo Durán-Silva. (2017) Acute corneal edema without epithelium compromise. A case report and literature review. Revista de la Facultad de Medicina 65:3, pages 513-519.
Crossref
Emily Khuc, Russell Bainer, Marie Wolf, Selene M. Clay, Daniel J. Weisenberger, Jacquelyn Kemmer, Valerie M. Weaver, David G. Hwang & Matilda F. Chan. (2017) Comprehensive characterization of DNA methylation changes in Fuchs endothelial corneal dystrophy. PLOS ONE 12:4, pages e0175112.
Crossref
Guadalupe VillarrealJr.Jr., Laura Kallay, Gustavo Vedana & Albert S. Jun. 2017. Current Treatment Options for Fuchs Endothelial Dystrophy. Current Treatment Options for Fuchs Endothelial Dystrophy 1 16 .
Esben Nielsen. (2016) Fuchs' endothelial corneal dystrophy: pathology and treatment outcome. Acta Ophthalmologica 94, pages 1-27.
Crossref
Maryam Ali, VijayKrishna Raghunathan, Jennifer Y. Li, Christopher J. Murphy & Sara M. Thomasy. (2016) Biomechanical relationships between the corneal endothelium and Descemet's membrane. Experimental Eye Research 152, pages 57-70.
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Justin T. Kwan, Kristine Dalton & Barry A. Weissman. (2016) Contact Lens Applications and the Corneal Dystrophies. Eye & Contact Lens: Science & Clinical Practice 42:3, pages 177-184.
Crossref
Jayne S. Weiss, Hans Ulrik Møller, Anthony J. Aldave, Berthold Seitz, Cecilie Bredrup, Tero Kivelä, Francis L. Munier, Christopher J. Rapuano, Kanwal K. Nischal, Eung Kweon Kim, John Sutphin, Massimo Busin, Antoine Labbé, Kenneth R. Kenyon, Shigeru Kinoshita & Walter Lisch. (2015) IC3D Classification of Corneal Dystrophies—Edition 2. Cornea 34:2, pages 117-159.
Crossref
Tero Kivelä, Elisabeth M. Messmer & Beata Rymgayłło-Jankowska. 2015. Eye Pathology. Eye Pathology 79 154 .

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