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Research Article

Design of CD40 Agonists and Their Use in Growing B Cells for Cancer Immunotherapy

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Pages 279-288 | Accepted 07 Jun 2012, Published online: 17 Jul 2012

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Karin Enell Smith, Adnan Deronic, Karin Hägerbrand, Per Norlén & Peter Ellmark. (2021) Rationale and clinical development of CD40 agonistic antibodies for cancer immunotherapy. Expert Opinion on Biological Therapy 21:12, pages 1635-1646.
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Articles from other publishers (22)

José Javier Morales-Núñez, José Francisco Muñoz-Valle, Mariel García-Chagollán, Sergio Cerpa-Cruz, Gloria Esther Martínez-Bonilla, Vianey Monserrat Medina-Rosales, Saúl Alberto Díaz-Pérez, Ferdinando Nicoletti & Jorge Hernández-Bello. (2023) Aberrant B-cell activation and B-cell subpopulations in rheumatoid arthritis: analysis by clinical activity, autoantibody seropositivity, and treatment. Clinical and Experimental Immunology.
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Cheri Peyton Goodall, Benjamin Schwarz, Ekaterina Selivanovitch, John Avera, Joseph Wang, Heini Miettinen & Trevor Douglas. (2021) Controlled Modular Multivalent Presentation of the CD40 Ligand on P22 Virus-like Particles Leads to Tunable Amplification of CD40 Signaling. ACS Applied Bio Materials 4:12, pages 8205-8214.
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Diana Stoycheva, Hasan Simsek, Willi Weber, Anja E. Hauser & Enrico Klotzsch. (2021) External cues to drive B cell function towards immunotherapy. Acta Biomaterialia 133, pages 222-230.
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Benjamin Shibru, Katharina Fey, Stephan Fricke, André-René Blaudszun, Friederike Fürst, Max Weise, Sabine Seiffert, Maria Katharina Weyh, Ulrike Köhl, Ulrich Sack & Andreas Boldt. (2021) Detection of Immune Checkpoint Receptors – A Current Challenge in Clinical Flow Cytometry. Frontiers in Immunology 12.
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Raquel Delgado, Karoline Kielbassa, Johanna ter Burg, Christian Klein, Christine Trumpfheller, Koen de Heer, Arnon P. Kater & Eric Eldering. (2021) Co-Stimulatory versus Cell Death Aspects of Agonistic CD40 Monoclonal Antibody Selicrelumab in Chronic Lymphocytic Leukemia. Cancers 13:12, pages 3084.
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Robby Divine, Ha V. Dang, George Ueda, Jorge A. Fallas, Ivan Vulovic, William Sheffler, Shally Saini, Yan Ting ZhaoInfencia Xavier Raj, Peter A. Morawski, Madeleine F. Jennewein, Leah J. Homad, Yu-Hsin Wan, Marti R. TooleyFranziska SeegerAli EtemadiMitchell L. Fahning, James Lazarovits, Alex Roederer, Alexandra C. Walls, Lance Stewart, Mohammadali Mazloomi, Neil P. King, Daniel J. Campbell, Andrew T. McGuire, Leonidas Stamatatos, Hannele Ruohola-Baker, Julie Mathieu, David Veesler & David Baker. (2021) Designed proteins assemble antibodies into modular nanocages. Science 372:6537.
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Peter D. Koch, Mikael J. Pittet & Ralph Weissleder. (2020) The chemical biology of IL-12 production via the non-canonical NFkB pathway . RSC Chemical Biology 1:4, pages 166-176.
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Frank Mickoleit, Valérie Jérôme, Ruth Freitag & Dirk Schüler. (2020) Bacterial Magnetosomes as Novel Platform for the Presentation of Immunostimulatory, Membrane‐Bound Ligands in Cellular Biotechnology. Advanced Biosystems 4:3, pages 1900231.
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Suresh de Silva, George Fromm, Casey W. Shuptrine, Kellsey Johannes, Arpita Patel, Kyung Jin Yoo, Kaiwen Huang & Taylor H. Schreiber. (2020) CD40 Enhances Type I Interferon Responses Downstream of CD47 Blockade, Bridging Innate and Adaptive Immunity. Cancer Immunology Research 8:2, pages 230-245.
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Jialing Zhang, Stephan S. Späth, Sherman M. Weissman & Samuel G. Katz. 2020. Cell Reprogramming for Immunotherapy. Cell Reprogramming for Immunotherapy 139 171 .
Valérie Jérôme, Ruth Freitag, Dirk Schüler & Frank Mickoleit. (2019) SEAP activity measurement in reporter cell-based assays using BCIP / NBT as substrate. Analytical Biochemistry 585, pages 113402.
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Fei Fei Guo & Jiu Wei Cui. (2019) The Role of Tumor-Infiltrating B Cells in Tumor Immunity. Journal of Oncology 2019, pages 1-9.
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Kerstin Wennhold, Alexander Shimabukuro-Vornhagen & Michael von Bergwelt-Baildon. (2019) B Cell-Based Cancer Immunotherapy. Transfusion Medicine and Hemotherapy 46:1, pages 36-46.
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James M. Mathew, Jessica H. Voss, Scott T. McEwen, Iwona Konieczna, Arjun Chakraborty, Xuemei Huang, Jie He, Lorenzo Gallon, Richard S. Kornbluth & Joseph R. Leventhal. (2018) Generation and Characterization of Alloantigen-Specific Regulatory T Cells For Clinical Transplant Tolerance. Scientific Reports 8:1.
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Manzoor M KhanManzoor M. Khan. 2016. Immunopharmacology. Immunopharmacology 397 425 .
Amer Assal, Justin Kaner, Gopichand Pendurti & Xingxing Zang. (2015) Emerging targets in cancer immunotherapy: beyond CTLA-4 and PD-1. Immunotherapy 7:11, pages 1169-1186.
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Ingegerd Elvers, Jason Turner-Maier, Ross Swofford, Michele Koltookian, Jeremy Johnson, Chip Stewart, Cheng-Zhong Zhang, Steven E. Schumacher, Rameen Beroukhim, Mara Rosenberg, Rachael Thomas, Evan Mauceli, Gad Getz, Federica Di Palma, Jaime F. Modiano, Matthew Breen, Kerstin Lindblad-Toh & Jessica Alföldi. (2015) Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background. Genome Research 25:11, pages 1634-1645.
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Karīna Siliņa, Undīne Rulle, Zane Kalniņa & Aija Linē. (2014) Manipulation of tumour-infiltrating B cells and tertiary lymphoid structures: a novel anti-cancer treatment avenue?. Cancer Immunology, Immunotherapy 63:7, pages 643-662.
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Sachin Gupta, James M. Termini, Francesca N. Raffa, Cindi-Ann Williams, Richard S. Kornbluth & Geoffrey W. Stone. (2014) Vaccination with a Fusion Protein That Introduces HIV-1 Gag Antigen into a Multitrimer CD40L Construct Results in Enhanced CD8 + T Cell Responses and Protection from Viral Challenge by Vaccinia-Gag . Journal of Virology 88:3, pages 1492-1501.
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Lee P. Richman & Robert H. Vonderheide. (2014) Role of Crosslinking for Agonistic CD40 Monoclonal Antibodies as Immune Therapy of Cancer. Cancer Immunology Research 2:1, pages 19-26.
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Edwin Bremer. (2013) Targeting of the Tumor Necrosis Factor Receptor Superfamily for Cancer Immunotherapy. ISRN Oncology 2013, pages 1-25.
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Ann L. White, H. T. Claude Chan, Ruth R. French, Stephen A. Beers, Mark S. Cragg, Peter W. M. Johnson & Martin J. Glennie. (2013) Fc?R??B controls the potency of agonistic anti-TNFR mAbs. Cancer Immunology, Immunotherapy 62:5, pages 941-948.
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