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Original Article

Autoreactive T Cells in Multiple Sclerosis

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Pages 183-201 | Received 26 May 1992, Published online: 10 Jul 2009

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Read on this site (2)

Hideki Garren. (2008) A DNA vaccine for multiple sclerosis. Expert Opinion on Biological Therapy 8:10, pages 1539-1550.
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Stuart Macphail. (1999) Superantigens: Mechanisms by which they may Induce, Exacerbate and Control Autoimmune Diseases. International Reviews of Immunology 18:1-2, pages 141-180.
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Jasmine Zouhair & Bryan Zouhair. (2022) Immunosenescence and Multiple Sclerosis: A Literature Review. Undergraduate Research in Natural and Clinical Science and Technology (URNCST) Journal 6:8, pages 1-10.
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Saige L. Pompura, David A. Hafler & Margarita Dominguez-Villar. (2022) Fatty Acid Metabolism and T Cells in Multiple Sclerosis. Frontiers in Immunology 13.
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Debanjana Chakravarty, Fareeha Saadi, Soumya Kundu, Abhishek Bose, Reas Khan, Kimberly Dine, Lawrence C. Kenyon, Kenneth S. Shindler & Jayasri Das Sarma. (2020) CD4 Deficiency Causes Poliomyelitis and Axonal Blebbing in Murine Coronavirus-Induced Neuroinflammation. Journal of Virology 94:14.
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Jun Young Park, Yeo Wool Kang & Won Gil Cho. (2019) Inflammasome-Mediated Inflammation in Neurodegenerative Diseases. The Open Neurology Journal 13:1, pages 55-62.
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Johan Linden, Gabriel Granåsen, Jonatan Salzer, Anders Svenningsson & Peter Sundström. (2019) Inflammatory activity and vitamin D levels in an MS population treated with rituximab. Multiple Sclerosis Journal - Experimental, Translational and Clinical 5:1, pages 205521731982659.
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Jun Shu, Xiaojuan He, Hong Li, Xue Liu, Xuemei Qiu, Tongliang Zhou, Ping Wang & Xiaojie Huang. (2018) The Beneficial Effect of Human Amnion Mesenchymal Cells in Inhibition of Inflammation and Induction of Neuronal Repair in EAE Mice. Journal of Immunology Research 2018, pages 1-10.
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Laure Michel, Melanie Chesneau, Philippe Manceau, Athenais Genty, Alexandra Garcia, Marion Salou, Annie Elong Ngono, Annaïck Pallier, Marylène Jacq-Foucher, Fabienne Lefrère, Sandrine Wiertlewski, Jean-Paul Soulillou, Nicolas Degauque, David-Axel Laplaud & Sophie Brouard. (2014) Unaltered regulatory B-cell frequency and function in patients with multiple sclerosis. Clinical Immunology 155:2, pages 198-208.
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Tanuja Chitnis & Samia J. Khoury. 2011. Multiple Sclerosis Therapeutics. Multiple Sclerosis Therapeutics 472 482 .
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Mrinalini Kala, Augusto Miravalle & Timothy Vollmer. (2011) Recent insights into the mechanism of action of glatiramer acetate. Journal of Neuroimmunology 235:1-2, pages 9-17.
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Xiao HU, Lei LOU, Jun YUAN, Xing WAN, Jian-yi WANG & Xin-yue QIN. (2010) Anti-inflammatory mechanism of selective estrogen receptor modulator in mice with experimental autoimmune encephalomyelitis. Academic Journal of Second Military Medical University 30:9, pages 946-951.
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Diego Gomez-Nicola, Alessandra Spagnolo, Carmen Guaza & Manuel Nieto-Sampedro. (2010) Aggravated experimental autoimmune encephalomyelitis in IL-15 knockout mice. Experimental Neurology 222:2, pages 235-242.
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J. Hong, H. Li, M. Chen, Y. C. Q. Zang, S. M. Skinner, J. M. Killian & J. Z. Zhang. (2009) Regulatory and pro-inflammatory phenotypes of myelin basic protein-autoreactive T cells in multiple sclerosis. International Immunology 21:12, pages 1329-1340.
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Jeffrey J. Bajramovic, Herbert P. M. Brok, Boudewijn Ouwerling, S. Anwar Jagessar, Linda van Straalen, Ivanela Kondova, Jan Bauer, Sandra Amor, Bert A. ‘t Hart & Avraham Ben-Nun. (2008) Oligodendrocyte-specific protein is encephalitogenic in rhesus macaques and induces specific demyelination of the optic nerve. European Journal of Immunology 38:5, pages 1452-1464.
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Luca Castelli, Cristoforo Comi, Annalisa Chiocchetti, Stefania Nicola, Riccardo Mesturini, Mara Giordano, Sandra D'Alfonso, Elisa Cerutti, Daniela Galimberti, Chiara Fenoglio, Fabiana Tesser, Junji Yagi, José Maria Rojo, Franco Perla, Maurizio Leone, Elio Scarpini, Francesco Monaco & Umberto Dianzani. (2007) ICOS gene haplotypes correlate with IL10 secretion and multiple sclerosis evolution. Journal of Neuroimmunology 186:1-2, pages 193-198.
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Tanuja Chitnis. 2007. The Neurobiology of Multiple Sclerosis. The Neurobiology of Multiple Sclerosis 43 72 .
Tanuja Chitnis & Samia J Khoury. (2003) Role of costimulatory pathways in the pathogenesis of multiple sclerosis and experimental autoimmune encephalomyelitis. Journal of Allergy and Clinical Immunology 112:5, pages 837-849.
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E Sarugeri, N Dozio, C Belloni, F Meschi, M R Pastore & E Bonifacio. (1998) Autoimmune responses to the β cell autoantigen, insulin, and the INS VNTR- IDDM2 locus . Clinical and Experimental Immunology 114:3, pages 370-376.
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Timothy B. Oriss, Paul Q. Hu & Timothy M. Wright. (2001) Distinct Autoreactive T Cell Responses to Native and Fragmented DNA Topoisomerase I: Influence of APC Type and IL-2. The Journal of Immunology 166:9, pages 5456-5463.
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Maria V. Tejada-Simon, Jian Hong, Victor M. Rivera & Jingwu Z. Zhang. (2001) Reactivity pattern and cytokine profile of T cells primed by myelin peptides in multiple sclerosis and healthy individuals. European Journal of Immunology 31:3, pages 907-917.
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Maria V. Tejada-Simon, Ying C. Q. Zang, Deye Yang, Jian Hong, Sufang Li, Rana A. K. Singh, Ella Van den Berg-Loonen, James M. Killian, Victor M. Rivera & Jingwu Z. Zhang. (2000) Aberrant T cell responses to myelin antigens during clinical exacerbation in patients with multiple sclerosis. International Immunology 12:12, pages 1641-1650.
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Johan Van Weyenbergh, Pawel Lipinski, Annie Abadie, Dorothée Chabas, Ulrich Blank, Roland Liblau & Juana Wietzerbin. (1998) Antagonistic Action of IFN-β and IFN-γ on High Affinity Fcγ Receptor Expression in Healthy Controls and Multiple Sclerosis Patients. The Journal of Immunology 161:3, pages 1568-1574.
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Martin H.G. Rep, Rogier Q. Hintzen, Chris H. Polman & RenéA.W. van Lier. (1996) Recombinant Interferon-β blocks proliferation but enhances interleukin-10 secretion by activated human T-cells. Journal of Neuroimmunology 67:2, pages 111-118.
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David A. Hafler, Mark G. Saadeh, Vijay K. Kuchroo, Edgar Milford & Lawrence Steinman. (1996) TCR usage in human and experimental demyelinating disease. Immunology Today 17:4, pages 152-159.
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Jingwu Zhang, Caroline Vandevyver, Piet Stinissen, Nadja Mertens, Ella van den Berg-Loonen & Jef Raus. (1995) Activation and clonal expansion of human Myelin Basic Protein-reactive T cells by bacterial superantigens. Journal of Autoimmunity 8:4, pages 615-632.
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Caroline Vandevyver, Nadja Mertens, Peter van den Elsen, Robert Medaer, Jef Raus & Jingwu Zhang. (2005) Clonal expansion of myelin basic protein‐reactive T cells in patients with multiple sclerosis: Restricted T cell receptor V gene rearrangements and CDR3 sequence. European Journal of Immunology 25:4, pages 958-968.
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T. Lohmann, M. Londei, R.D.G. Leslie, M. Hawa, M. Geysen & S. Rodda. (1994) Immunodominant epitopes of glutamic acid decarboxylase 65 and 67 in insulin-dependent diabetes mellitus. The Lancet 343:8913, pages 1607-1608.
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Jingwu Zhang & Jef Raus. (1994) Myelin basic protein-reactive T cells in multiple sclerosis: Pathologic relevance and therapeutic targeting. Cytotechnology 16:3, pages 181-187.
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Jingwu Zhang & Jef Raus. (1993) T-cell vaccination in autoimmune diseases from laboratory to clinic. Human Immunology 38:2, pages 87-96.
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