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Original Article

The Concept of Type-1 and Type-2 Helper T Cells and Their Cytokines in Humans

Pages 427-455 | Received 30 Sep 1996, Published online: 10 Jul 2009

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R. A. Ajjan & A. P. Weetman. (2014) New understanding of the role of cytokines in the pathogenesis of Graves’ ophthalmopathy. Journal of Endocrinological Investigation 27:3, pages 237-245.
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Crossref
Michel Fougereau. 2002. Encyclopedia of Molecular Biology. Encyclopedia of Molecular Biology.
Steffen Pelzl, Gerhard Opelz, Manfred Wiesel, Peter Schnülle, Constanze Schönemann, Bernd Döhler & Caner Süsal. (2002) SOLUBLE CD30 AS A PREDICTOR OF KIDNEY GRAFT OUTCOME1. Transplantation 73:1, pages 3-6.
Crossref
Jean Bousquet, Paul van Cauwenberge & Nikolai Khaltaev. (2001) Allergic Rhinitis and Its Impact on Asthma. Journal of Allergy and Clinical Immunology 108:5, pages S147-S334.
Crossref
Kohsuke Masutani, Mitsuteru Akahoshi, Kazuhiko Tsuruya, Masanori Tokumoto, Toshiharu Ninomiya, Tsutomu Kohsaka, Kyoichi Fukuda, Hidetoshi Kanai, Hitoshi Nakashima, Takeshi Otsuka & Hideki Hirakata. (2001) Predominance of Th1 immune response in diffuse proliferative lupus nephritis. Arthritis & Rheumatism 44:9, pages 2097-2106.
Crossref
Fritz E Lower, Santosh Menon & Juan A Sanchez. (2001) Association of parvovirus B19 with plasma cell–rich myocardial infiltrates after heart transplantation. The Journal of Heart and Lung Transplantation 20:7, pages 755-758.
Crossref
Piero Stratta, Alessandra Messuerotti, Caterina Canavese, Mirella Coen, Luigi Luccoli, Benedetta Bussolati, Laura Giorda, Pasquale Malavenda, Maria Cacciabue, Massimiliano Bugiani, Mario Bo, Manuel Ventura, Giovanni Camussi & Bice Fubini. (2001) The role of metals in autoimmune vasculitis: epidemiological and pathogenic study. Science of The Total Environment 270:1-3, pages 179-190.
Crossref
Ilja Střı́ž, Tadashi Mio, Yuichi Adachi, Stefano Carnevali, Debra J. Romberger & Stephen I. Rennard. (2000) Effects of interferons alpha and gamma on cytokine production and phenotypic pattern of human bronchial epithelial cells. International Journal of Immunopharmacology 22:8, pages 573-585.
Crossref
A Von Ruecker & I.G.H Schmidt-Wolf. (2000) Strategies to evaluate metabolic stress and catabolism by means of immunological variables. Clinical Nutrition 19:3, pages 147-156.
Crossref
M Itoh, K Uchimura, M Makino, T Kobayashi, R Hayashi, M Nagata, H Kakizawa, K Fujiwara & A Nagasaka. (2000) PRODUCTION OF IL-10 AND IL-12 IN CD40 AND INTERLEUKIN 4-ACTIVATED MONONUCLEAR CELLS FROM PATIENTS WITH GRAVES' DISEASE. Cytokine 12:6, pages 688-693.
Crossref
Van Anh Nguyen, Roswitha Sgonc, Hermann Dietrich & Georg Wick. (2000) Endothelial Injury in Internal Organs of University of California at Davis Line 200 (UCD 200) Chickens, an Animal Model for Systemic Sclerosis (Scleroderma). Journal of Autoimmunity 14:2, pages 143-149.
Crossref
Johnny T. StineChristi WoodMark HillAngela EppCarol J. RaportVicki L. SchweickartYoshio EndoTakuma SasakiGraham SimmonsChris BoshoffPaul ClaphamYuan ChangPatrick MoorePatrick W. GrayDavid Chantry. (2000) KSHV-encoded CC chemokine vMIP-III is a CCR4 agonist, stimulates angiogenesis, and selectively chemoattracts TH2 cells. Blood 95:4, pages 1151-1157.
Crossref
Emanuelle Trannoy, Rosemarie Berger, Georges Holländer, Fabrice Bailleux, Pierre Heimendinger, Delphine Vuillier & Hervé Creusvaux. (2000) Vaccination of immunocompetent elderly subjects with a live attenuated Oka strain of varicella zoster virus: a randomized, controlled, dose-response trial. Vaccine 18:16, pages 1700-1706.
Crossref
LINA MATERA & MARCELLA MORI. (2006) Cooperation of Pituitary Hormone Prolactin with Interleukin-2 and Interleukin-12 on Production of Interferon-γ by Natural Killer and T Cells. Annals of the New York Academy of Sciences 917:1, pages 505-513.
Crossref
Cristina Mapp, Piera Boschetto, Deborah Miotto, Edoardo De Rosa & Leonardo M. Fabbri. (1999) Mechanisms of occupational asthma. Annals of Allergy, Asthma & Immunology 83:6, pages 645-664.
Crossref
V. K. Singh, S. Mehrotra & S. S. Agarwal. (1999) The paradigm of Th1 and Th2 cytokines. Immunologic Research 20:3, pages 147-161.
Crossref
Lisa M. Austin, Maki Ozawa, Toyoko Kikuchi, Ian B. Walters & James G. Krueger. (1999) The Majority of Epidermal T Cells in Psoriasis Vulgaris Lesions can Produce Type 1 Cytokines, Interferon-γ, Interleukin-2, and Tumor Necrosis Factor-α, Defining TC1 (Cytotoxic T Lymphocyte) and TH1 Effector Populations:1 a Type 1 Differentiation Bias is also Measured in Circulating Blood T Cells in Psoriatic Patients. Journal of Investigative Dermatology 113:5, pages 752-759.
Crossref
N. Hida, T. Shimoyama, P. Neville, M. F. Dixon, A. T. Axon, S. Shimoyama T & J. E. Crabtree. (1999) Increased expression of IL-10 and IL-12 (p40) mRNA in Helicobacter pylori infected gastric mucosa: relation to bacterial cag status and peptic ulceration. Journal of Clinical Pathology 52:9, pages 658-664.
Crossref
György Haskó & Csaba Szabó. (2009) IL‐12 as a therapeutic target for pharmacological modulation in immune‐mediated and inflammatory diseases: regulation of T helper 1/T helper 2 responses. British Journal of Pharmacology 127:6, pages 1295-1304.
Crossref
Marcela F Pasetti, Richard J Anderson, Fernando R Noriega, Myron M Levine & Marcelo B Sztein. (1999) Attenuated ΔguaBA Salmonella typhi Vaccine Strain CVD 915 as a Live Vector Utilizing Prokaryotic or Eukaryotic Expression Systems to Deliver Foreign Antigens and Elicit Immune Responses. Clinical Immunology 92:1, pages 76-89.
Crossref
RONALD L. WILDER & ILIA J. ELENKOV. (1999) Hormonal Regulation of Tumor Necrosis Factor-alpha, Interleukin-12 and Interleukin-10 Production by Activated Macrophages: A Disease-modifying Mechanism in Rheumatoid Arthritis and Systemic Lupus Erythematosus?. Annals of the New York Academy of Sciences 876:1 NEUROENDOCRIN, pages 14-31.
Crossref
C.G. BegleyN.A. Nicola. (1999) Resolving Conflicting Signals: Cross Inhibition of Cytokine Signaling Pathways. Blood 93:5, pages 1443-1447.
Crossref
C.G. BegleyN.A. Nicola. (1999) Resolving Conflicting Signals: Cross Inhibition of Cytokine Signaling Pathways. Blood 93:5, pages 1443-1447.
Crossref
Mark D. Mannie. (1999) Immunological self/nonself discrimination. Immunologic Research 19:1, pages 65-87.
Crossref
Diane E. Griffin. 1999. Encyclopedia of Virology. Encyclopedia of Virology 339 344 .
Margaret Wang, Andrew Saxon & David Diaz-Sanchez. (1999) Early IL-4 Production Driving Th2 Differentiation in a Humanin VivoAllergic Model Is Mast Cell Derived. Clinical Immunology 90:1, pages 47-54.
Crossref
Geneviève Milon & Yasmine Belkaid. (1998) Cytokines et infection. Annales de l'Institut Pasteur / Actualités 9:2, pages 107-120.
Crossref

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