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Laboratory Studies

Notch2/Hes-1 Pathway Plays an Important Role in Renal Ischemia and Reperfusion Injury-Associated Inflammation and Apoptosis and the γ-Secretase Inhibitor DAPT has a Nephroprotective Effect

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Pages 207-216 | Received 20 Sep 2010, Accepted 14 Dec 2010, Published online: 18 Feb 2011

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Qiaoqi Zhang, Lei Xie, Lin Jiang, Jiaqing Ni, Wenke Han, Xiuhua Mi & Ping Wang. (2022) Icariin attenuates renal fibrosis in vivo and in vitro by inhibiting the Notch2/Hes-1 pathway. Growth Factors 40:1-2, pages 26-36.
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Rong Tang, Xiangcheng Xiao, Yang Lu, Huihui Li, Qiaoling Zhou, Patrick Kwadwo Nuro-Gyina & Xia Li. (2020) Interleukin-22 attenuates renal tubular cells inflammation and fibrosis induced by TGF-β1 through Notch1 signaling pathway. Renal Failure 42:1, pages 381-390.
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Haluk Ilhan, Murat Eroglu, Volkan Inal, Yusuf Emrah Eyi, Ibrahim Arziman, Ali Osman Yildirim, Ali Tansel, Günalp Uzun & Levent Yamanel. (2012) Hyperbaric Oxygen Therapy Alleviates Oxidative Stress and Tissue Injury in Renal Ischemia/Reperfusion Injury in Rats. Renal Failure 34:10, pages 1305-1308.
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