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Renal Failure Volume 33, 2011 - Issue 4
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Case Report

Prolonged Hemodialysis for Severe Metformin Intoxication

Stephen I. Rifkin Division of Nephrology and Hypertension, Department of Internal Medicine, College of Medicine, University of South Florida, Tampa, FL, USACorrespondence[email protected]
,
Christopher McFarren Division of Nephrology and Hypertension, Department of Internal Medicine, College of Medicine, University of South Florida, Tampa, FL, USA
,
Raghu Juvvadi Division of Nephrology and Hypertension, Department of Internal Medicine, College of Medicine, University of South Florida, Tampa, FL, USA
&
Samuel S. Weinstein Tampa General Medical Group, Tampa General Hospital, Tampa, FL, USA
Pages 459-461 | Received 07 Dec 2010, Accepted 23 Feb 2011, Published online: 30 Apr 2011

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S. Vecchio, A. Giampreti, V. M. Petrolini, D. Lonati, A. Protti, P. Papa, C. Rognoni, A. Valli, L. Rocchi, L. Rolandi, L. Manzo & C. A. Locatelli. (2014) Metformin accumulation: Lactic acidosis and high plasmatic metformin levels in a retrospective case series of 66 patients on chronic therapy. Clinical Toxicology 52:2, pages 129-135.
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S. A. Al-Abri, S. Hayashi, K. L. Thoren & K. R. Olson. (2013) Metformin overdose-induced hypoglycemia in the absence of other antidiabetic drugs. Clinical Toxicology 51:5, pages 444-447.
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Articles from other publishers (15)

Hannah V. Reynolds, Hamish H. G. Pollock, Yogesh V. ApteAlexis Tabah. (2022) Achieving High Dialysis Dose via Continuous Renal Replacement Therapy in the Setting of Metformin Associated Lactic Acidosis. A Case Series. A&A Practice 16:1, pages e01561.
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Ibrahim Mohammed, Morley D. Hollenberg, Hong Ding & Chris R. Triggle. (2021) A Critical Review of the Evidence That Metformin Is a Putative Anti-Aging Drug That Enhances Healthspan and Extends Lifespan. Frontiers in Endocrinology 12.
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Mohummad Shaan Goonoo, Rebecca Morris, Ajay Raithatha & Fionuala Creagh. (2021) Republished: Metformin-associated lactic acidosis: reinforcing learning points. Drug and Therapeutics Bulletin 59:8, pages 124-127.
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Céline Bellefroid, Pierre Goffin, Julien Guntz & Marine Deville. (2020) Metformin-Induced Lactic Acidosis: A Question of Time. Case Reports in Critical Care 2020, pages 1-4.
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Mohummad Shaan Goonoo, Rebecca Morris, Ajay Raithatha & Fionuala Creagh. (2020) Metformin-associated lactic acidosis: reinforcing learning points. BMJ Case Reports 13:9, pages e235608.
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George Sam Wang & Christopher Hoyte. (2018) Review of Biguanide (Metformin) Toxicity. Journal of Intensive Care Medicine 34:11-12, pages 863-876.
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Jian-Da Lu & Jun Xue. 2019. Critical Care Nephrology. Critical Care Nephrology 600 629.e7 .
David Cucchiari, Manuel Alfredo Podestà, Elisa Merizzoli, Albania Calvetta, Emanuela Morenghi, Claudio Angelini, Claudio Ponticelli & Salvatore Badalamenti. (2016) Dose-related effects of metformin on acid–base balance and renal function in patients with diabetes who develop acute renal failure: a cross-sectional study. Acta Diabetologica 53:4, pages 551-558.
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Aibek E. Mirrakhimov, Aram Barbaryan, Adam Gray & Taha Ayach. (2016) The Role of Renal Replacement Therapy in the Management of Pharmacologic Poisonings. International Journal of Nephrology 2016, pages 1-12.
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Janna H. Villano, Charles W. O’Connell, Binh T. Ly & Aaron Schneir. (2015) Case Files from the University of California San Diego Health System Fellowship Coma and Severe Acidosis: Remember to Consider Acetaminophen. Journal of Medical Toxicology 11:3, pages 368-376.
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Diane P. Calello, Kathleen D. Liu, Timothy J. Wiegand, Darren M. Roberts, Valéry Lavergne, Sophie Gosselin, Robert S. Hoffman, Thomas D. Nolin & Marc Ghannoum. (2015) Extracorporeal Treatment for Metformin Poisoning. Critical Care Medicine 43:8, pages 1716-1730.
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John M. Miles, Andrew D. Rule & Barry A. Borlaug. (2014) Use of Metformin in Diseases of Aging. Current Diabetes Reports 14:6.
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Dieter Müller & Herbert Desel. (2013) Common Causes of Poisoning. Deutsches Ärzteblatt international.
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Kathryn T. Kopec & Michael J. Kowalski. (2012) Metformin-Associated Lactic Acidosis (MALA): Case Files of the Einstein Medical Center Medical Toxicology Fellowship. Journal of Medical Toxicology 9:1, pages 61-66.
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Ngan Lam, Gurbir Sekhon & Andrew A. House. (2012) Metformin-Associated Lactic Acidosis following Intentional Overdose Successfully Treated with Tris-Hydroxymethyl Aminomethane and Renal Replacement Therapy. Case Reports in Nephrology 2012, pages 1-5.
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