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Renal Failure Volume 36, 2014 - Issue 10
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Research Article

Urinary netrin-1 and KIM-1 as early biomarkers for septic acute kidney injury

Yuexing TuIntensive Care Unit, Zhejiang Provincial People's Hospital HangzhouChina
,
Hui WangIntensive Care Unit, The Affiliated Hospital of Hangzhou Normal University HangzhouChina
,
Renhua SunIntensive Care Unit, Zhejiang Provincial People's Hospital HangzhouChina
,
Yin NiIntensive Care Unit, Zhejiang Provincial People's Hospital HangzhouChina
,
Leilei MaIntensive Care Unit, Zhejiang Provincial People's Hospital HangzhouChina
,
Fei XvDepartment of Laboratory Medicine, Zhejiang Provincial People's Hospital HangzhouChina
,
Xiuping HuIntensive Care Unit, Zhejiang Provincial People's Hospital HangzhouChina
,
Lingzhi JiangIntensive Care Unit, Zhejiang Provincial People's Hospital HangzhouChina
,
Aiping WuIntensive Care Unit, Zhejiang Provincial People's Hospital HangzhouChina
,
Xv ChenIntensive Care Unit, Zhejiang Provincial People's Hospital HangzhouChina
,
Minhua ChenIntensive Care Unit, Zhejiang Provincial People's Hospital HangzhouChina
,
Jingquan LiuIntensive Care Unit, Zhejiang Provincial People's Hospital HangzhouChina
&
Fang HanIntensive Care Unit, Zhejiang Provincial People's Hospital HangzhouChinaCorrespondence[email protected]
 show all
Pages 1559-1563 | Received 28 May 2014, Accepted 15 Jul 2014, Published online: 26 Aug 2014

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Xiaobing Li, Xianghua Liu, Ji Li, ELi Song, Ning Sun, Wen Liu, Tian Wang, Jinchang Yang & Zhenzhen Li. (2018) Semaphorin-3A and Netrin-1 predict the development of kidney injury in children with congenital hydronephrosis. Scandinavian Journal of Clinical and Laboratory Investigation 78:1-2, pages 55-61.
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Wei Wei, Yibo Zhao, Yan Zhang, Songtao Shou & Heng Jin. (2023) The early diagnosis and pathogenic mechanisms of sepsis-related acute kidney injury. Open Life Sciences 18:1.
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Jiatong Xu, Jiaying Li, Yan Li, Xiaoxiao Shi, Huadong Zhu & Limeng Chen. (2023) Multidimensional Landscape of SA-AKI Revealed by Integrated Proteomics and Metabolomics Analysis. Biomolecules 13:9, pages 1329.
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Camila Eleuterio Rodrigues & Zoltán H. Endre. (2022) Definitions, phenotypes, and subphenotypes in acute kidney injury—Moving towards precision medicine. Nephrology 28:2, pages 83-96.
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Barbara Infante, Francesca Conserva, Paola Pontrelli, Serena Leo, Alessandra Stasi, Marco Fiorentino, Dario Troise, Andrea dello Strologo, Carlo Alfieri, Loreto Gesualdo, Giuseppe Castellano & Giovanni Stallone. (2023) Recent advances in molecular mechanisms of acute kidney injury in patients with diabetes mellitus. Frontiers in Endocrinology 13.
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文敬 李. (2022) Research Progress in Early Prediction of Sep-tic Associated Acute Kidney Injury. Advances in Clinical Medicine 12:08, pages 8071-8076.
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Dominik Jarczak, Stefan Kluge & Axel Nierhaus. (2021) Sepsis—Pathophysiology and Therapeutic Concepts. Frontiers in Medicine 8.
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Chenxiao Liu, Qi Li, Xiu Feng & Qian Li. (2018) Elevated levels of netrin-1 in the serum of patients with diabetic nephropathy: Relationship with renal function and inflammation. European Journal of Inflammation 16, pages 205873921880928.
Crossref
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M. Cardenas-Gonzalez, M. Pavkovic & V.S. Vaidya. 2018. Comprehensive Toxicology. Comprehensive Toxicology 147 163 .
Rajit K. Basu. 2018. Critical Care Nephrology and Renal Replacement Therapy in Children. Critical Care Nephrology and Renal Replacement Therapy in Children 81 98 .
Jiao Liu, Guang Li, Lianghai Li, Zhiyong Liu, Qingshan Zhou, Guirong Wang & Dechang Chen. (2017) Surfactant protein-D (SP-D) gene polymorphisms and serum level as predictors of susceptibility and prognosis of acute kidney injury in the Chinese population. BMC Nephrology 18:1.
Crossref
Yiming Shao, Yinqiang Fan, Yuliu Xie, Lu Yin, Yuanli Zhang, Liehua Deng, Xiaocong Sun, Xin Shao, Xinzhang Tan, Junbing He & Shiman Zhao. (2017) Effect of continuous renal replacement therapy on kidney injury molecule-1 and neutrophil gelatinase-associated lipocalin in patients with septic acute kidney injury. Experimental and Therapeutic Medicine 13:6, pages 3594-3602.
Crossref
Paraskevi Pavlakou, Vassilios Liakopoulos, Theodoros Eleftheriadis, Michael Mitsis & Evangelia Dounousi. (2017) Oxidative Stress and Acute Kidney Injury in Critical Illness: Pathophysiologic Mechanisms—Biomarkers—Interventions, and Future Perspectives. Oxidative Medicine and Cellular Longevity 2017, pages 1-11.
Crossref
C.L. Edelstein. 2017. Biomarkers of Kidney Disease. Biomarkers of Kidney Disease 241 315 .
Marlies E. van Wolfswinkel, Liese C. Koopmans, Dennis A. Hesselink, Ewout J. Hoorn, Rob Koelewijn, Jaap J. van Hellemond & Perry J. J. van Genderen. (2016) Neutrophil gelatinase-associated lipocalin (NGAL) predicts the occurrence of malaria-induced acute kidney injury. Malaria Journal 15:1.
Crossref
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Crossref
Daniel J. Kilburn, Kiran Shekar & John F. Fraser. (2016) The Complex Relationship of Extracorporeal Membrane Oxygenation and Acute Kidney Injury: Causation or Association?. BioMed Research International 2016, pages 1-14.
Crossref
Kevin J. Downes & Stuart L. Goldstein. 2016. Biomarkers in Kidney Disease. Biomarkers in Kidney Disease 689 718 .
Ling-Xin Chen & Jay L. Koyner. (2015) Biomarkers in Acute Kidney Injury. Critical Care Clinics 31:4, pages 633-648.
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Crossref
Bai-Sheng Gong & Qiang Feng. (2015) Netrin-1: The new tumor markers in renal clear cell carcinoma. Asian Pacific Journal of Tropical Medicine 8:6, pages 489-493.
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Suzana Bojic, Jelena Kotur-Stevuljevic, Nevena Kalezic, Predrag Stevanovic, Zorana Jelic-Ivanovic, Dragoljub Bilanovic, Lidija Memon, Mladen Damnjanovic, Zdravko Kalaba & Sanja Simic-Ogrizovic. (2015) Diagnostic Value of Matrix Metalloproteinase-9 and Tissue Inhibitor of Matrix Metalloproteinase-1 in Sepsis-Associated Acute Kidney Injury. The Tohoku Journal of Experimental Medicine 237:2, pages 103-109.
Crossref
Rashid Alobaidi, Rajit K. Basu, Stuart L. Goldstein & Sean M. Bagshaw. (2015) Sepsis-Associated Acute Kidney Injury. Seminars in Nephrology 35:1, pages 2-11.
Crossref
Kevin J. Downes & Stuart L. Goldstein. 2015. Biomarkers in Kidney Disease. Biomarkers in Kidney Disease 1 30 .

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