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Laboratory Study

Protective effect of sitagliptin against renal ischemia reperfusion injury in rats

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Pages 687-693 | Received 30 Jun 2014, Accepted 04 Jan 2015, Published online: 23 Feb 2015

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Suat Tekin, Asiye Beytur, Murat Cakir, Aslı Taslıdere, Yavuz Erden, Cigdem Tekin & Suleyman Sandal. (2022) Protective effect of saxagliptin against renal ischaemia reperfusion injury in rats. Archives of Physiology and Biochemistry 128:3, pages 608-618.
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Tavga Ahmed Aziz. (2021) Cardioprotective Effect of Quercetin and Sitagliptin in Doxorubicin-Induced Cardiac Toxicity in Rats. Cancer Management and Research 13, pages 2349-2357.
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Iman O. Sherif, Alaa A. Alshaalan & Nora H. Al-Shaalan. (2020) Renoprotective effect of vildagliptin following hepatic ischemia/reperfusion injury. Renal Failure 42:1, pages 208-215.
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Zheen Aorahman Ahmed, Aso Nihad Abtar, Hemn Hassan Othman & Tavga Ahmed Aziz. (2019) Effects of quercetin, sitagliptin alone or in combination in testicular toxicity induced by doxorubicin in rats. Drug Design, Development and Therapy 13, pages 3321-3329.
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Articles from other publishers (13)

Ahmed B. Hamed, Hanan S. El-Abhar, Dalaal M. Abdallah, Kawkab A. Ahmed & Yasmin S. Abulfadl. (2023) Prunetin in a GPR30-dependent manner mitigates renal ischemia/reperfusion injury in rats via interrupting indoxyl sulfate/TLR4/TRIF, RIPK1/RIPK3/MLKL, and RIPK3/PGAM5/DRP-1 crosstalk. Saudi Pharmaceutical Journal 31:11, pages 101818.
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Eslam Hassan, Shady Allam, Ahmed M. Mansour, Aya Shaheen & Salama A. Salama. (2022) The potential protective effects of estradiol and 2-methoxyestradiol in ischemia reperfusion-induced kidney injury in ovariectomized female rats. Life Sciences 296, pages 120441.
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Małgorzata Krzystek-Korpacka, Mariusz G. Fleszar, Paulina Fortuna, Kinga Gostomska-Pampuch, Łukasz Lewandowski, Tomasz Piasecki, Bogna Kosyk, Adam Szeląg & Małgorzata Trocha. (2021) Modulation of Prostanoids Profile and Counter-Regulation of SDF-1α/CXCR4 and VIP/VPAC2 Expression by Sitagliptin in Non-Diabetic Rat Model of Hepatic Ischemia-Reperfusion Injury. International Journal of Molecular Sciences 22:23, pages 13155.
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Małgorzata Trocha, Mariusz G. Fleszar, Paulina Fortuna, Łukasz Lewandowski, Kinga Gostomska-Pampuch, Tomasz Sozański, Anna Merwid-Ląd & Małgorzata Krzystek-Korpacka. (2021) Sitagliptin Modulates Oxidative, Nitrative and Halogenative Stress and Inflammatory Response in Rat Model of Hepatic Ischemia-Reperfusion. Antioxidants 10:8, pages 1168.
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Hailei SunZhengchun ZhouHaiyang XuanZhongya Yan. (2021) Anti-inflammatory and protective effects of combined treatment with sitagliptin and melatonin in cardiac ischemia reperfusion injury in obese rats: Involvement of TLR-4/NF-κB pathway. European Journal of Inflammation 19, pages 205873922110662.
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Walaa Yehia Abdelzaher, Remon Roshdy Rofaeil, Doaa Mohamed Elroby Ali & Mina Ezzat Attya. (2019) Protective effect of dipeptidyl peptidase-4 inhibitors in testicular torsion/detorsion in rats: a possible role of HIF-1α and nitric oxide. Naunyn-Schmiedeberg's Archives of Pharmacology 393:4, pages 603-614.
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Małgorzata Trocha, Małgorzata Krzystek-Korpacka, Anna Merwid-Ląd, Beata Nowak, Małgorzata Pieśniewska, Piotr Dzięgiel, Agnieszka Gomułkiewicz, Przemysław Kowalski, Dorota Diakowska, Adam Szeląg & Tomasz Sozański. (2019) Sitagliptin-Dependent Differences in the Intensity of Oxidative Stress in Rat Livers Subjected to Ischemia and Reperfusion. Oxidative Medicine and Cellular Longevity 2019, pages 1-10.
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Nada M. Kamel, Mai A. Abd El Fattah, Hanan S. El-Abhar & Dalaal M. Abdallah. (2019) Novel repair mechanisms in a renal ischaemia/reperfusion model: Subsequent saxagliptin treatment modulates the pro-angiogenic GLP-1/cAMP/VEGF, ANP/eNOS/NO, SDF-1α/CXCR4, and Kim-1/STAT3/HIF-1α/VEGF/eNOS pathways. European Journal of Pharmacology 861, pages 172620.
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A.J. Scheen & P. Delanaye. (2018) Renal outcomes with dipeptidyl peptidase-4 inhibitors. Diabetes & Metabolism 44:2, pages 101-111.
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Marcel H. A. Muskiet, Lennart Tonneijck, Mark M. Smits, Michaël J.B. van Baar, Mark H. H. Kramer, Ewout J. Hoorn, Jaap A. Joles & Daniël H. van Raalte. (2017) GLP-1 and the kidney: from physiology to pharmacology and outcomes in diabetes. Nature Reviews Nephrology 13:10, pages 605-628.
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Hossein Fatemikia, Mohammad Seyedabadi, Zynab Karimi, Kiarash Tanha, Majid Assadi & Kaveh Tanha. (2017) Comparison of 99mTc-DMSA renal scintigraphy with biochemical and histopathological findings in animal models of acute kidney injury. Molecular and Cellular Biochemistry 434:1-2, pages 163-169.
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Christoph Reichetzeder, Karoline von Websky, Oleg Tsuprykov, Azadeh Mohagheghi Samarin, Luise Gabriele Falke, Sulistyo Emantoko Dwi Putra, Ahmed Abdallah Hasan, Viktoriia Antonenko, Caterina Curato, Jörg Rippmann, Thomas Klein & Berthold Hocher. (2017) Head-to-head comparison of structurally unrelated dipeptidyl peptidase 4 inhibitors in the setting of renal ischemia reperfusion injury. British Journal of Pharmacology 174:14, pages 2273-2286.
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Anton Ivanovich Korbut & Vadim Valerievich Klimontov. (2016) Incretin-based therapy: renal effects. Diabetes mellitus 19:1, pages 53-63.
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