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Laboratory Study

Metformin alleviated EMT and fibrosis after renal ischemia–reperfusion injury in rats

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Pages 614-621 | Received 05 Oct 2015, Accepted 26 Jan 2016, Published online: 26 Feb 2016

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Feng Wang, Chen Xu Zhou, Zhi Zheng, Du Juan Li, Wen Li & Yun Zhou. (2023) Metformin reduces myogenic contracture and myofibrosis induced by rat knee joint immobilization via AMPK-mediated inhibition of TGF-β1/Smad signaling pathway. Connective Tissue Research 64:1, pages 26-39.
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Lei Zhang, Xiaochun Zhang, Lihua Guan, Daxin Zhou & Junbo Ge. (2023) AMPK/mTOR-mediated therapeutic effect of metformin on myocardial ischaemia reperfusion injury in diabetic rat. Acta Cardiologica 78:1, pages 64-71.
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E Lioudaki, M Whyte, ES Androulakis, KG Stylianou, EK Daphnis & ES Ganotakis. (2017) Renal Effects of SGLT‐2 Inhibitors and Other Anti‐diabetic Drugs: Clinical Relevance and Potential Risks. Clinical Pharmacology & Therapeutics 102:3, pages 470-480.
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Kerui Fan, Kejia Wu, Ling Lin, Pu Ge, Jie Dai, Xiaojiao He, Kai Hu & Li Zhang. (2017) Metformin mitigates carbon tetrachloride-induced TGF-?1/Smad3 signaling and liver fibrosis in mice. Biomedicine & Pharmacotherapy 90, pages 421-426.
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