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Original Article

Treatment with Sulfatide or its Precursor, Galactosylceramide, Prevents Diabetes in NOD Mice

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Pages 9-17 | Received 26 May 2000, Accepted 20 Oct 2000, Published online: 07 Jul 2009

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Nadir Kadri, Maria Blomqvist & Susanna L Cardell. (2008) Type II natural killer T cells: a new target for immunomodulation?. Expert Review of Clinical Immunology 4:5, pages 615-627.
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Lijing SuMuhammad AthamnaYing WangJunmei WangMarina Freudenberg, Tao YueJianhui WangEva Marie Y. Moresco, Haoming HeTsaffrir Zor & Bruce Beutler. (2021) Sulfatides are endogenous ligands for the TLR4–MD-2 complex. Proceedings of the National Academy of Sciences 118:30.
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Ewa Gurgul-Convey. (2020) Sphingolipids in Type 1 Diabetes: Focus on Beta-Cells. Cells 9:8, pages 1835.
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Ismail Syed, Maria F. Rubin de Celis, James F. Mohan, Pedro M. Moraes-Vieira, Archana Vijayakumar, Andrew T. Nelson, Dionicio Siegel, Alan Saghatelian, Diane Mathis & Barbara B. Kahn. (2019) PAHSAs attenuate immune responses and promote β cell survival in autoimmune diabetic mice. Journal of Clinical Investigation 129:9, pages 3717-3731.
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Shu-Xia Wang, Chun-Lin Yang, Min Zhang, Peng Zhang, Ru-Tao Liu, Na Zhang, Bing Yang, Xiao-Li Li, Ying-Chun Dou & Rui-Sheng Duan. (2019) Sulfatides ameliorate experimental autoimmune neuritis by suppressing Th1/Th17 cells. Journal of Neuroimmunology 326, pages 55-61.
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Avadhesh Kumar Singh, Prabhanshu Tripathi & Susanna L. Cardell. (2018) Type II NKT Cells: An Elusive Population With Immunoregulatory Properties. Frontiers in Immunology 9.
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Laurits J. Holm, Martin Haupt-Jorgensen, Jesper Larsen, Jano D. Giacobini, Mesut Bilgin & Karsten Buschard. (2018) L-serine supplementation lowers diabetes incidence and improves blood glucose homeostasis in NOD mice. PLOS ONE 13:3, pages e0194414.
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S. Rhost, L. Löfbom, J.-E. Månsson, A. Lehuen, M. Blomqvist & S. L. Cardell. (2014) Administration of Sulfatide to Ameliorate Type I Diabetes in Non-Obese Diabetic Mice. Scandinavian Journal of Immunology 79:4, pages 260-266.
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Jakob Ørskov Sørensen, Karsten Buschard & Carl-Henrik Brogren. (2014) The preventive role of type 2 NKT cells in the development of type 1 diabetes. APMIS 122:3, pages 167-182.
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Caroline Tao, Angelica Sifuentes & William L. Holland. (2014) Regulation of glucose and lipid homeostasis by adiponectin: Effects on hepatocytes, pancreatic β cells and adipocytes. Best Practice & Research Clinical Endocrinology & Metabolism 28:1, pages 43-58.
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Karsten Buschard, Jan-Eric Månsson, Bart O. Roep & Tatjana Nikolic. (2012) Self-Glycolipids Modulate Dendritic Cells Changing the Cytokine Profiles of Committed Autoreactive T Cells. PLoS ONE 7:12, pages e52639.
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Carolina de Lourdes Julião Vieira Rocha, Adeir Moreira Rocha Júnior, Beatriz Julião Vieira Aarestrup & Fernando Monteiro Aarestrup. (2012) Inibição da expressão de ciclooxigenase 2 em feridas cutâneas de camundongos NOD submetidos à terapia a laser de baixa intensidade. Jornal Vascular Brasileiro 11:3, pages 175-181.
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Tadanobu Takahashi & Takashi Suzuki. (2012) Role of sulfatide in normal and pathological cells and tissues. Journal of Lipid Research 53:8, pages 1437-1450.
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Lakshmimathy Subramanian, Hartley Blumenfeld, Robert Tohn, Dalam Ly, Carlos Aguilera, Igor Maricic, Jan-Eric Mansson, Karsten Buschard, Vipin Kumar & Terry L. Delovitch. (2012) NKT Cells Stimulated by Long Fatty Acyl Chain Sulfatides Significantly Reduces the Incidence of Type 1 Diabetes in Nonobese Diabetic Mice. PLoS ONE 7:5, pages e37771.
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KARSTEN BUSCHARD. (2011) What causes type 1 diabetes? Lessons from animal models. APMIS 119:s132, pages 1-19.
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Karsten Buschard, Axel Kornerup Hansen, Karen Jensen, Dicky J. Lindenbergh-Kortleve, Lilian F. de Ruiter, Thomas C. Krohn, Majbritt R. Hufeldt, Finn K. Vogensen, Bent Aasted, Thomas Osterbye, Bart O. Roep, Colin de Haar & Edward E. Nieuwenhuis. (2011) Alcohol Facilitates CD1d Loading, Subsequent Activation of NKT Cells, and Reduces the Incidence of Diabetes in NOD Mice. PLoS ONE 6:4, pages e17931.
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Janet M. Wenzlau, Leah Sheridan & John C. Hutton. 2011. Immunoendocrinology: Scientific and Clinical Aspects. Immunoendocrinology: Scientific and Clinical Aspects 15 39 .
Todd E. Fox & Mark Kester. 2010. Sphingolipids as Signaling and Regulatory Molecules. Sphingolipids as Signaling and Regulatory Molecules 206 216 .
Mikhail Bogdanov, Eugenia Mileykovskaya & William Dowhan. 2008. Lipids in Health and Disease. Lipids in Health and Disease 197 239 .
Michal Levy, Nicolas Garmy, Ehud Gazit & Jacques Fantini. (2006) The minimal amyloid‐forming fragment of the islet amyloid polypeptide is a glycolipid‐binding domain. The FEBS Journal 273:24, pages 5724-5735.
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K. Buschard, M. Blomqvist, T. Osterbye & P. Fredman. (2005) Involvement of sulfatide in beta cells and type 1 and type 2 diabetes. Diabetologia 48:10, pages 1957-1962.
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Maria Blomqvist, Anne Kaas, Jan‐Eric Månsson, Bent Formby, Britt‐Marie Rynmark, Karsten Buschard & Pam Fredman. (2003) Developmental expression of the type I diabetes related antigen sulfatide and sulfated lactosylceramide in mammalian pancreas. Journal of Cellular Biochemistry 89:2, pages 301-310.
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