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Original Article

The NOD Mouse as a Model of SLE

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Pages 53-64 | Received 02 Jun 2000, Accepted 29 Sep 2000, Published online: 07 Jul 2009

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Read on this site (2)

François D. Dufour, Alan G. Baxter & Pablo A. Silveira. (2008) Interactions between B-Lymphocytes and Type 1 NKT Cells in Autoimmune Diabetes. Journal of Immunotoxicology 5:2, pages 249-257.
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Andres Rojas, FingPing Xu, Mauricio Rojas & James W. Thomas. (2003) Structure and Function of CD72 in the Non-obese Diabetic (NOD) Mouse. Autoimmunity 36:4, pages 233-239.
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Articles from other publishers (37)

Robert Root-Bernstein, Kaylie Chiles, Jack Huber, Alison Ziehl, Miah Turke & Maja Pietrowicz. (2023) Clostridia and Enteroviruses as Synergistic Triggers of Type 1 Diabetes Mellitus. International Journal of Molecular Sciences 24:9, pages 8336.
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Teri M. Greiling, Carina Dehner, Xinguo Chen, Kevin Hughes, Alonso J. Iñiguez, Marco Boccitto, Daniel Zegarra Ruiz, Stephen C. Renfroe, Silvio M. Vieira, William E. Ruff, Soyeong Sim, Christina KriegelJulia Glanternik, Xindi Chen, Michael GirardiPatrick DegnanKaren H. Costenbader, Andrew L. Goodman, Sandra L. Wolin & Martin A. Kriegel. (2018) Commensal orthologs of the human autoantigen Ro60 as triggers of autoimmunity in lupus. Science Translational Medicine 10:434.
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Edward P.F. Chu, Colleen M. Elso, Abigail H. Pollock, May A. Alsayb, Leanne Mackin, Helen E. Thomas, Thomas W.H. Kay, Pablo A. Silveira, Ashley S. Mansell, Katharina Gaus & Thomas C. Brodnicki. (2017) Disruption of Serinc1, which facilitates serine-derived lipid synthesis, fails to alter macrophage function, lymphocyte proliferation or autoimmune disease susceptibility. Molecular Immunology 82, pages 19-33.
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Phuc T. Dang, Quyen Bui, Claretta S. D’Souza & Jacqueline M. Orian. 2015. Emerging and Evolving Topics in Multiple Sclerosis Pathogenesis and Treatments. Emerging and Evolving Topics in Multiple Sclerosis Pathogenesis and Treatments 143 177 .
Anna E. Kersh, Lindsay J. Edwards & Brian D. Evavold. (2014) Progression of Relapsing-Remitting Demyelinating Disease Does Not Require Increased TCR Affinity or Epitope Spread. The Journal of Immunology 193:9, pages 4429-4438.
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Sydney K. Elizer, Andrew F. Marshall & Daniel J. Moore. (2014) Dysregulation of T Lymphocyte Proliferative Responses in Autoimmunity. PLoS ONE 9:8, pages e106347.
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Stanford L. Peng. 2012. Autoimmunity. Autoimmunity 135 168 .
Socorro Miranda-Hernandez, Nicole Gerlach, Julie M. Fletcher, Erik Biros, Matthias Mack, Heinrich Körner & Alan G. Baxter. (2011) Role for MyD88, TLR2 and TLR9 but Not TLR1, TLR4 or TLR6 in Experimental Autoimmune Encephalomyelitis. The Journal of Immunology 187:2, pages 791-804.
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Dwight H. Kono & Argyrios N. Theofilopoulos. 2011. Systemic Lupus Erythematosus. Systemic Lupus Erythematosus 63 105 .
M E Stern, C S Schaumburg, R Dana, M Calonge, J Y Niederkorn & S C Pflugfelder. (2010) Autoimmunity at the ocular surface: pathogenesis and regulation. Mucosal Immunology 3:5, pages 425-442.
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Béatrice Regnault, José Osorio y Fortea, Dongmei Miao, George Eisenbarth & Evie Melanitou. (2009) Early over expression of messenger RNA for multiple genes, including insulin, in the Pancreatic Lymph Nodes of NOD mice is associated with Islet Autoimmunity. BMC Medical Genomics 2:1.
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Xiaoyan Xiao, Peng Zhao, Daniel Rodriguez-Pinto, Dake Qi, Octavian Henegariu, Lena Alexopoulou, Richard A. Flavell, F. Susan Wong & Li Wen. (2009) Inflammatory Regulation by TLR3 in Acute Hepatitis. The Journal of Immunology 183:6, pages 3712-3719.
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Xiaoyan Xiao, Bin Ma, Baojun Dong, Peng Zhao, Ningwen Tai, Li Chen, F. Susan Wong & Li Wen. (2009) Cellular and humoral immune responses in the early stages of diabetic nephropathy in NOD mice. Journal of Autoimmunity 32:2, pages 85-93.
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Margaret A. Jordan & Alan G. Baxter. (2008) The genetics of immunoregulatory T cells. Journal of Autoimmunity 31:3, pages 237-244.
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Julie M. Fletcher, Margaret A. Jordan, Sarah L. Snelgrove, Robyn M. Slattery, François D. Dufour, Konstantinos Kyparissoudis, Gurdyal S. Besra, Dale I. Godfrey & Alan G. Baxter. (2008) Congenic Analysis of the NKT Cell Control Gene Nkt2 Implicates the Peroxisomal Protein Pxmp4 . The Journal of Immunology 181:5, pages 3400-3412.
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Grant Morahan, Lois Balmer & Donald Monley. (2008) Establishment of “The Gene Mine”: a resource for rapid identification of complex trait genes. Mammalian Genome 19:6, pages 390-393.
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Antony Basten. (2007) The evolution of clinical immunology and allergy in Australia. Immunology & Cell Biology 86:1, pages 16-21.
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Margaret A. Jordan, Julie M. Fletcher, Daniel Pellicci & Alan G. Baxter. (2007) Slamf1 , the NKT Cell Control Gene Nkt1 . The Journal of Immunology 178:3, pages 1618-1627.
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Stella Mayo & Anthony Quinn. (2007) Altered susceptibility to EAE in congenic NOD mice: Altered processing of the encephalitogenic MOG35–55 peptide by NOR/LtJ mice. Clinical Immunology 122:1, pages 91-100.
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Pablo A. Silveira, Harold D. Chapman, Jessica Stolp, Ellis Johnson, S. Lewis Cox, Kara Hunter, Linda S. Wicker & David V. Serreze. (2006) Genes within the Idd5 and Idd9/11 Diabetes Susceptibility Loci Affect the Pathogenic Activity of B Cells in Nonobese Diabetic Mice . The Journal of Immunology 177:10, pages 7033-7041.
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Dwight H. Kono & Argyrios N. Theofilopoulos. (2006) Genetics of SLE in mice. Springer Seminars in Immunopathology 28:2, pages 83-96.
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Pablo A. Silveira & Shane T. Grey. (2006) B cells in the spotlight: innocent bystanders or major players in the pathogenesis of type 1 diabetes. Trends in Endocrinology & Metabolism 17:4, pages 128-135.
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Bronwyn A. O'Brien, Xuan Geng, Catherine H. Orteu, Yongqian Huang, Mehran Ghoreishi, YiQun Zhang, Jason A. Bush, Gang Li, Diane T. Finegood & Jan Peter Dutz. (2006) A deficiency in the in vivo clearance of apoptotic cells is a feature of the NOD mouse. Journal of Autoimmunity 26:2, pages 104-115.
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Bao-You Xu, Hua Yang, David V. Serreze, Rebecca MacIntosh, Weiming Yu & James R. WrightJrJr. (2005) Rapid Destruction of Encapsulated Islet Xenografts by NOD Mice is CD4-Dependent and Facilitated by B-cells: Innate Immunity and Autoimmunity Do Not Play Significant Roles. Transplantation 80:3, pages 402-409.
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Daniel J. Moore, Hooman Noorchashm, Tina H. Lin, Siri A. Greeley & Ali Naji. (2005) NOD B-cells Are Insufficient to Incite T-Cell-Mediated Anti-islet Autoimmunity. Diabetes 54:7, pages 2019-2025.
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Mark S. AndersonJeffrey A. Bluestone. (2005) THE NOD MOUSE: A Model of Immune Dysregulation. Annual Review of Immunology 23:1, pages 447-485.
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James L Mobley. (2004) Is rheumatoid arthritis a consequence of natural selection for enhanced tuberculosis resistance?. Medical Hypotheses 62:5, pages 839-843.
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G. Ravel, M. Christ, F. Horand & J. Descotes. (2004) Autoimmunity, environmental exposure and vaccination: is there a link?. Toxicology 196:3, pages 211-216.
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. 2004. Immunotoxicology of Drugs and Chemicals: an Experimental and Clinical Approach - Volume I: Principles and Methods of Immunotoxicology. Immunotoxicology of Drugs and Chemicals: an Experimental and Clinical Approach - Volume I: Principles and Methods of Immunotoxicology 205 217 .
Michelle Solomon & Nora Sarvetnick. 2004. 239 264 .
Dwight H. Kono, Roberto Baccalà & Argyrios N. Theofilopoulos. 2004. Systemic Lupus Erythematosus. Systemic Lupus Erythematosus 225 263 .
Luis M. Esteban, Tatiana Tsoutsman, Margaret A. Jordan, Daniel Roach, Lynn D. Poulton, Andrew Brooks, Olga V. Naidenko, Stephane Sidobre, Dale I. Godfrey & Alan G. Baxter. (2003) Genetic Control of NKT Cell Numbers Maps to Major Diabetes and Lupus Loci. The Journal of Immunology 171:6, pages 2873-2878.
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Diane L. Sewell, Emily K. Reinke, Dominic O. Co, Laura H. Hogan, Robert B. Fritz, Matyas Sandor & Zsuzsa Fabry. (2003) Infection with Mycobacterium bovis BCG Diverts Traffic of Myelin Oligodendroglial Glycoprotein Autoantigen-Specific T Cells Away from the Central Nervous System and Ameliorates Experimental Autoimmune Encephalomyelitis . Clinical and Vaccine Immunology 10:4, pages 564-572.
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Ute C. Rogner & Philip Avner. (2003) Congenic mice: cutting tools for complex immune disorders. Nature Reviews Immunology 3:3, pages 243-252.
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Todd Pearson, Thomas G. Markees, Linda S. Wicker, David V. Serreze, Laurence B. Peterson, John P. Mordes, Aldo A. Rossini & Dale L. Greiner. (2003) NOD Congenic Mice Genetically Protected From Autoimmune Diabetes Remain Resistant to Transplantation Tolerance Induction. Diabetes 52:2, pages 321-326.
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J. Lang & D. Bellgrau. (2002) A T‐Cell Functional Phenotype Common among Autoimmune‐Prone Rodent Strains. Scandinavian Journal of Immunology 55:6, pages 546-559.
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M. Flodström, F.-D. Shi, N. Sarvetnick & H.-G. Ljunggren. (2002) The Natural Killer Cell - Friend or Foe in Autoimmune Disease?. Scandinavian Journal of Immunology 55:5, pages 432-441.
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