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Review Article

The deubiquitinase A20 in immunopathology of autoimmune diseases

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Pages 307-319 | Received 05 Jun 2013, Accepted 01 Mar 2014, Published online: 27 Mar 2014

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Pershang Farshi, Rahul R Deshmukh, Joseph O Nwankwo, Richard T Arkwright, Boris Cvek, Jinbao Liu & Q Ping Dou. (2015) Deubiquitinases (DUBs) and DUB inhibitors: a patent review. Expert Opinion on Therapeutic Patents 25:10, pages 1191-1208.
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Xiaowei Shi, Tian Qian, Min Li, Fangru Chen, Yan Chen & Fei Hao. (2015) Aberrant Low Expression of A20 in Tumor Necrosis Factor-α-stimulated SLE Monocytes Mediates Sustained NF-κB Inflammatory Response. Immunological Investigations 44:5, pages 497-508.
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Prakash Kumar, Pawan Kumar, Debabrata Mandal & Ravichandiran Velayutham. (2022) The emerging role of Deubiquitinases (DUBs) in parasites: A foresight review. Frontiers in Cellular and Infection Microbiology 12.
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Simona Perga, Francesca Montarolo, Serena Martire, Brigitta Bonaldo, Gabriele Bono, Jessica Bertolo, Roberta Magliozzi & Antonio Bertolotto. (2020) Overexpression of the ubiquitin‐editing enzyme A20 in the brain lesions of Multiple Sclerosis patients: moving from systemic to central nervous system inflammation. Brain Pathology 31:2, pages 283-296.
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Lu Zhang, Yao Yao, Junmei Tian, Wanlan Jiang, Shiliang Zhou, Jinyun Chen, Ting Xu & Min Wu. (2020) Alterations and abnormal expression of A20 in peripheral monocyte subtypes in patients with rheumatoid arthritis. Clinical Rheumatology 40:1, pages 341-348.
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Weinan Guo, Jinyuan Ma, Sen Guo, Huina Wang, Sijia Wang, Qiong Shi, Lin Liu, Tao Zhao, Fengfan Yang, Shuyang Chen, Jianru Chen, Jianhong Zhao, Chen Yu, Xiuli Yi, Yuqi Yang, Jingjing Ma, Qingrong Ni, Guannan Zhu, Tianwen Gao & Chunying Li. (2020) A20 regulates the therapeutic effect of anti-PD-1 immunotherapy in melanoma. Journal for ImmunoTherapy of Cancer 8:2, pages e001866.
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Qiang Chen, Kai-Peng Sun, Jiang-Shan Huang, Zeng-Chun Wang & Zhi-Nuan Hong. (2020) Resveratrol attenuates neuroinflammation after deep hypothermia with circulatory arrest in rats. Brain Research Bulletin 155, pages 145-154.
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Qi Bao, Chong Li, Chongfeng Xu, Ruiying Zhang, Kai Zhao & Ziyuan Duan. (2018) Porcine enterocyte protein Btnl5 negatively regulates NF-kappa B pathway by interfering p65 nuclear translocation. Gene 646, pages 47-55.
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Upneet K. Sokhi, Mark P. Liber, Laura Frye, Sungho Park, Kyuho Kang, Tania Pannellini, Baohong Zhao, Rada Norinsky, Lionel B. Ivashkiv & Shiaoching Gong. (2018) Dissection and function of autoimmunity-associated TNFAIP3 (A20) gene enhancers in humanized mouse models. Nature Communications 9:1.
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Zhaoyou Meng, Pan Gao, Lin Chen, Jing Peng, Jialu Huang, Min Wu, Kangning Chen & Zhenhua Zhou. (2017) Artificial Zinc-Finger Transcription Factor of A20 Suppresses Restenosis in Sprague Dawley Rats after Carotid Injury via the PPARα Pathway. Molecular Therapy - Nucleic Acids 8, pages 123-131.
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Simona Perga, Serena Martire, Francesca Montarolo, Nicole D. Navone, Andrea Calvo, Giuseppe Fuda, Alberto Marchet, Daniela Leotta, Adriano Chiò & Antonio Bertolotto. (2017) A20 in Multiple Sclerosis and Parkinson’s Disease: Clue to a Common Dysregulation of Anti-Inflammatory Pathways?. Neurotoxicity Research 32:1, pages 1-7.
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Wei-Lin Jin, Xiao-Yuan Mao & Guan-Zhong Qiu. (2017) Targeting Deubiquitinating Enzymes in Glioblastoma Multiforme: Expectations and Challenges. Medicinal Research Reviews 37:3, pages 627-661.
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Zhaoyou Meng, Ting Zhao, Kai Zhou, Qi Zhong, Yanchun Wang, Xiaoyi Xiong, Faxiang Wang, Yuanrui Yang, Wenyao Zhu, Juan Liu, Maofan Liao, Lirong Wu, Chunmei Duan, Jie Li, Qiuwen Gong, Liang Liu, Ao Xiong, Meihua Yang, Jian Wang & Qingwu Yang. (2017) A20 Ameliorates Intracerebral Hemorrhage–Induced Inflammatory Injury by Regulating TRAF6 Polyubiquitination. The Journal of Immunology 198:2, pages 820-831.
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Avital Eisenberg-Lerner, Ifat Regev & Yifat Merbl. 2017. Proteomics for Drug Discovery. Proteomics for Drug Discovery 139 152 .
Jessica A. Hamerman, Jessica Pottle, Minjian Ni, Yantao He, Zhong-Yin Zhang & Jane H. Buckner. (2016) Negative regulation of TLR signaling in myeloid cells-implications for autoimmune diseases. Immunological Reviews 269:1, pages 212-227.
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Jun Wang & Robert J. Schwartz. 2016. Congenital Heart Diseases: The Broken Heart. Congenital Heart Diseases: The Broken Heart 173 202 .
Matthew S. Hayden & Sankar Ghosh. (2014) Regulation of NF-κB by TNF family cytokines. Seminars in Immunology 26:3, pages 253-266.
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