62
Views
30
CrossRef citations to date
0
Altmetric
Original Article

A Role for Macrophages in the Pathogenesis of Type 1 Diabetes

&
Pages 145-155 | Received 09 Dec 1988, Published online: 07 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Helga Rothe & Hubert Kolb. (1998) The APC1 Concept of Type I Diabetes. Autoimmunity 27:3, pages 179-184.
Read now

Articles from other publishers (29)

Bart O. Roep, Sofia Thomaidou, René van Tienhoven & Arnaud Zaldumbide. (2020) Type 1 diabetes mellitus as a disease of the β-cell (do not blame the immune system?). Nature Reviews Endocrinology.
Crossref
Dana M. PreviteJon D. Piganelli. (2018) Reactive Oxygen Species and Their Implications on CD4 + T Cells in Type 1 Diabetes . Antioxidants & Redox Signaling 29:14, pages 1399-1414.
Crossref
Gina M. Coudriet, Dana M. Previte & Jon D. Piganelli. 2016. Redox-Active Therapeutics. Redox-Active Therapeutics 647 667 .
Jaime Haidet, Vincenza Cifarelli, Xuehui Geng, Massimo Trucco & Patrizia Luppi. 2012. Diabetes & C-Peptide. Diabetes & C-Peptide 111 127 .
Sergio A. Lira, Abel Viejo‐Borbolla, Limin Shang & Andrea P. Martin. 2009. Chemokines, Part A. Chemokines, Part A 193 207 .
Andrea P. Martin, Jennifer M. Alexander-Brett, Claudia Canasto-Chibuque, Alexandre Garin, Jonathan S. Bromberg, Daved H. Fremont & Sergio A. Lira. (2007) The Chemokine Binding Protein M3 Prevents Diabetes Induced by Multiple Low Doses of Streptozotocin. The Journal of Immunology 178:7, pages 4623-4631.
Crossref
Daniel R. Johnson, Jason C. O'Connor, Ansuman Satpathy & Gregory G. Freund. 2006. Interleukins. Interleukins 405 441 .
Thorsten Zacher, Ina Knerr, Wolfgang Rascher, Joachim R. Kalden & Ralf Wassmuth. (2002) Characterization of Monocyte-Derived Dendritic Cells in Recent-Onset Diabetes Mellitus Type 1. Clinical Immunology 105:1, pages 17-24.
Crossref
Lorenzo Piemonti, Biagio Eugenio Leone, Rita Nano, Alessandra Saccani, Paolo Monti, Paola Maffi, Giancarlo Bianchi, Antonio Sica, Giuseppe Peri, Raffaella Melzi, Luca Aldrighetti, Antonio Secchi, Valerio Di Carlo, Paola Allavena & Federico Bertuzzi. (2002) Human Pancreatic Islets Produce and Secrete MCP-1/CCL2: Relevance in Human Islet Transplantation. Diabetes 51:1, pages 55-65.
Crossref
J.B. Classen & D.C. Classen. (2001) Vaccines and the risk of insulin-dependent diabetes (IDDM): potential mechanism of action. Medical Hypotheses 57:5, pages 532-538.
Crossref
Sabine Bieg, William Simonson, Kristian Ellefsen & ???ke Lernmark. (2000) Rel B Is an Early Marker of Autoimmune Islet Inflammation in the BioBreeding (BB) Rat. Pancreas 20:1, pages 47-54.
Crossref
Janusz My?liwiec, Adam Kr?towski, Maciej Kinalski & Ida Kinalska. (1999) CD11a Expression and soluble ICAM-1 levels in peripheral blood in high-risk and overt type 1 diabetes subjects. Immunology Letters 70:1, pages 69-72.
Crossref
Abha Saini, Yue J. Liu, David J. Cohen & Boon S. Ooi. (1996) Hyperglycemia augments macrophage growth responses to colony-stimulating factor-1. Metabolism 45:9, pages 1125-1129.
Crossref
T. Mandrup-Poulsen. (1996) The role of interleukin-1 in the pathogenesis of IDDM. Diabetologia 39:9, pages 1005-1029.
Crossref
H. Rothe, V. Burkart, A. Faust & H. Kolb. (1996) Interleukin-12 gene expression is associated with rapid development of diabetes mellitus in non-obese diabetic mice. Diabetologia 39:1, pages 119-122.
Crossref
Yue J. Liu, Abha Saini, David J. Cohen & Boon S. Ooi. (1995) Modulation of macrophage proliferation by hyperglycemia. Molecular and Cellular Endocrinology 114:1-2, pages 187-192.
Crossref
F. A. Gries, H. Kolb & T. Koschinsky. 1995. Oxidative Stress and Aging. Oxidative Stress and Aging 191 201 .
A. J. Davies, A. J. Bone, T. J. Wilkin, D. R. Cole & H. Rokos. (1994) Serum biopterin — a novel marker for immune activation during pre-diabetes in the BB rat. Diabetologia 37:5, pages 466-470.
Crossref
Thomas Mandrup-Poulsen, Urs Zumsteg, Jesper Reimers, Flemming Pociot, Lise Mørch, Steffen Helqvist, Charles A. Dinarello & Jørn Nerup. (1993) Involvement of interleukin 1 and interleukin 1 antagonist in pancreatic β-cell destruction in insulin-dependent diabetes mellitus. Cytokine 5:3, pages 185-191.
Crossref
Volker Burkart, Yoichiro Imai, Boris Kallmann & Hubert Kolb. (2001) Cyclosporin A protects pancreatic islet cells from nitric oxide‐dependent macrophage cytotoxicity. FEBS Letters 313:1, pages 56-58.
Crossref
Daniël Pipeleers & Zhidong Ling. (1992) Pancreatic beta cells in insulin-dependent diabetes. Diabetes / Metabolism Reviews 8:3, pages 209-227.
Crossref
T.E. Mandel. 1992. Molecular Immunology. Molecular Immunology 157 196 .
CLAUDE C.A. BERNARD, TOM E. MANDEL & IAN R. MACKAY. 1992. The Autoimmune Diseases II. The Autoimmune Diseases II 47 106 .
Jürgen Zielasek & Hubert Kolb. (1992) Ganglioside therapy of type I diabetes: Enhancement of hyperglycemia in the low dose streptozotocin model. Life Sciences 51:1, pages 49-52.
Crossref
Leonard C. Harrison. (1991) Transgenic approaches to understanding the role of MHC genes in insulin dependent diabetes mellitus I. Immune and non-immune mechanisms of ? cell destruction. Bailli?re's Clinical Endocrinology and Metabolism 5:3, pages 439-448.
Crossref
J. MØLVIG, F. POCIOT, L. BÆK, H. WORSAAE, L. DALL WOGENSEN, P. CHRISTENSEN, L. STAUB‐NIELSEN, T. MANDRUP‐POULSEN, K. MANOGUE & J. NERUP. (2006) Monocyte Function in IDDM Patients and Healthy Individuals. Scandinavian Journal of Immunology 32:3, pages 297-311.
Crossref
J. Allison, L. C. Harrison, I. L. Campbell & J. F. A. P. Miller. 1990. The Role of Viruses and the Immune System in Diabetes Mellitus. The Role of Viruses and the Immune System in Diabetes Mellitus 121 135 .
H. Kolb & V. Kolb-Bachofen. 1990. The Molecular Biology of Autoimmune Disease. The Molecular Biology of Autoimmune Disease 313 323 .
R. Mirakian, A. Ciampolillo, U. Deuss, A. Miyazaki & G. F. Bottazzo. 1990. The Role of Micro-organisms in Non-infectious Diseases. The Role of Micro-organisms in Non-infectious Diseases 131 154 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.