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Original Article

A Human Anti-Cardiolipin Autoantibody is Encoded by Developmentally restricted Heavy and Light Chain Variable Region Genes

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Pages 97-105 | Received 04 Jun 1990, Published online: 07 Jul 2009

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Arthur Hohmann, Ewa Cairns, Michael Brisco, David A. Bell & Betty Diamond. (1995) Immunoglobulin Gene Sequence Anlaysis of Anti-Cardiolipin and Anti-Cardiolipin Idiotype (H3) Human Monoglonal Antibodies. Autoimmunity 22:1, pages 49-57.
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Hwee-Ming Cheng. (1994) Cryptic Antiphospholipid Autoantibodies and Serum Co-Inhibitors. Autoimmunity 19:2, pages 127-133.
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Articles from other publishers (23)

I Giles, A Lambrianides & A Rahman. (2008) Examining the non-linear relationship between monoclonal antiphospholipid antibody sequence, structure and function. Lupus 17:10, pages 895-903.
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M D DALEY, V MISENER, T OLEE, P P CHEN & K A SIMINOVITCH. (1993) Genetic analysis of the variable region genes encoding a monospecific human natural anti-DNA antibody. Clinical and Experimental Immunology 93:1, pages 11-18.
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X MARIETTE, Y LEVY, M-L DUBREUIL, L INTRATOR, F DANON & J-C BROUET. (1993) Characterization of a human monoclonal autoantibody directed to cardiolipin/β2 glycoprotein I produced by chronic lymphocytic leukaemia B cells. Clinical and Experimental Immunology 94:2, pages 385-390.
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George F. WidhopfIIII, Craig J. GoldbergTraci L. ToyLaura Z. RassentiWilliam G. WierdaJohn C. ByrdMichael J. KeatingJohn G. Gribben, Kanti R. Rai & Thomas J. Kipps. (2008) Nonstochastic pairing of immunoglobulin heavy and light chains expressed by chronic lymphocytic leukemia B cells is predicated on the heavy chain CDR3. Blood 111:6, pages 3137-3144.
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Ian P. Giles, David A. Isenberg & Anisur Rahman. 2006. Hughes Syndrome. Hughes Syndrome 470 491 .
George F. WidhopfIIIILaura Z. RassentiTraci L. ToyJohn G. GribbenWilliam G. WierdaThomas J. Kipps. (2004) Chronic lymphocytic leukemia B cells of more than 1% of patients express virtually identical immunoglobulins. Blood 104:8, pages 2499-2504.
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George F. WidhopfIIII, Diana C. Brinson, Thomas J. Kipps & Helen Tighe. (2004) Transgenic Expression of a Human Polyreactive Ig Expressed in Chronic Lymphocytic Leukemia Generates Memory-Type B Cells That Respond to Nonspecific Immune Activation. The Journal of Immunology 172:4, pages 2092-2099.
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CONSTANTIN A. BONA & FREDA K. STEVENSON. 2004. Molecular Biology of B Cells. Molecular Biology of B Cells 381 401 .
Ian P. Giles, Joanna D. Haley, Sylvia Nagl, David A. Isenberg, David S. Latchman & Anisur Rahman. (2003) A systematic analysis of sequences of human antiphospholipid and anti–β2-glycoprotein I antibodies: The importance of somatic mutations and certain sequence motifs. Seminars in Arthritis and Rheumatism 32:4, pages 246-265.
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Harald Burkhardt & Reinhard E. Voll. 2003. Molekularmedizinische Grundlagen von rheumatischen Erkrankungen. Molekularmedizinische Grundlagen von rheumatischen Erkrankungen 165 211 .
George F. WidhopfIIII & Thomas J. Kipps. (2001) Normal B Cells Express 51p1 -Encoded Ig Heavy Chains That Are Distinct From Those Expressed by Chronic Lymphocytic Leukemia B Cells . The Journal of Immunology 166:1, pages 95-102.
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A. Rahman & D. Isenberg. 2000. Hughes Syndrome. Hughes Syndrome 358 371 .
Miri Blank, Ari Waisman, Edna Mozes, Takao Koike & Yehuda Shoenfeld. (1999) Characteristics and pathogenic role of anti-β2-glycoprotein I single-chain Fv domains: induction of experimental antiphospholipid syndrome. International Immunology 11:12, pages 1917-1926.
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Reginald U. Chukwuocha, Elie T. Hsiao, Peter Shaw, Joseph L. Witztum & Pojen P. Chen. (1999) Isolation, Characterization and Sequence Analysis of Five IgG Monoclonal Anti-β2-Glycoprotein-1 and Anti-Prothrombin Antigen-Binding Fragments Generated by Phage Display. The Journal of Immunology 163:8, pages 4604-4611.
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Hans‐Peter Brezinschek, Ruth I Brezinschek, Thomas DÖrner & Peter E Lipsky. (2001) Similar characteristics of the CDR3 of V H 1‐69/DP‐10 rearrangements in normal human peripheral blood and chronic lymphocytic leukaemia B cells . British Journal of Haematology 102:2, pages 516-521.
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D.A. Isenberg, C.T. Ravirajan, A. Rahman & J. Kalsi. (2016) The role of antibodies to DNA in systemic lupus erythematosus— A review and introduction to an international workshop on DNA antibodies held in London, May 1996. Lupus 6:3, pages 290-304.
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S Menon, M.A.A Rahman, C.T Ravirajan, D Kandiah, C.M Longhurst, T McNally, W.M Williams, D.S Latchman & D.A Isenberg. (1997) The Production, Binding Characteristics and Sequence Analysis of Four Human IgG Monoclonal Antiphospholipid Antibodies. Journal of Autoimmunity 10:1, pages 43-57.
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Anisur Rahman, Sanjeev Menon, David S. Latchman & David A. Isenberg. (1996) Sequences of monoclonal antiphospholipid antibodies: variations on an anti-DNA antibody theme. Seminars in Arthritis and Rheumatism 26:2, pages 515-525.
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P.‐M. YANG, T. OLEE, D. A. CARSON & P. P. CHEN. (2008) Characterization of Two Highly Homologous Autoantibody‐Related VHl Genes in Humans. Scandinavian Journal of Immunology 37:4, pages 504-508.
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Vincent Hurez, Srinivas‐ V. Kaveri & Michel D. Kazatchkine. (2005) Expression and control of the natural autoreactive IgG repertoire in normal human serum. European Journal of Immunology 23:4, pages 783-789.
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INGRID RANDEN, KEITHM. THOMPSON, VIRGINIA PASCUAL, KIMBFRLY VICTOR, DENNIS BHALR, JOHN COADWELL, ØYSTEIN FORRE, J. DONALD CAPRA & JACOBB. NATVIG. (2006) Rheumatoid Factor V Genes from Patients with Rheumatoid Arthritis are Diverse and Show Evidence of an Antigen‐Driven Response. Immunological Reviews 128:1, pages 49-71.
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Ton LOGTENBERG, MIEKEE. M. SSCHUTTE, SASKIA B. EBELING, FRITS H. J. GMELIG‐MEYLING & JOHAN H. VAN ES. (2006) Molecular Approaches to the Study of Human B‐Cell and (Auto)antibody Repertoire Generation and Selection. Immunological Reviews 128:1, pages 23-47.
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M. M. NEWKIRK. (2006) Complete Amino Acid Sequence of the Variable Regions of Two Highly Related Heavy and Light Chains of Human IgG (SFL) and IgM (RIV) Rheumatoid Factors. Scandinavian Journal of Immunology 35:6, pages 651-658.
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