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Autoimmunity Volume 10, 1991 - Issue 4
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Original Article

Human Monoclonal Thyroglobulin Autoantibodies of High Affinity. I. Production, Characterisation and Interaction with Murine Monoclonal Thyroglobulin Antibodies

N. Fukuma Endocrine Immunology Unit, Department of Medicine, University of Wales College of Medicine, Heath Park, Cardiff, UK
,
V. B. Petersen RSR Ltd., Avenue Park, Pentwyn, Cardiff, UK
,
S. M. McLachlan Endocrine Immunology Unit, Department of Medicine, University of Wales College of Medicine, Heath Park, Cardiff, UK
,
C. A.S. Pegg Department of Surgery, University of Nottingham, UK
&
B. Rees Smith Endocrine Immunology Unit, Department of Medicine, University of Wales College of Medicine, Heath Park, Cardiff, UK
Pages 291-295 | Received 14 Jun 1991, Published online: 07 Jul 2009

Citations (20)

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Read on this site (2)

Takashi Akamizu. (2003) Monoclonal Antibodies to Thyroid Specific Autoantigens. Autoimmunity 36:6-7, pages 361-366.
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M. Horimoto, V. S. Petersen, C. A. S. Pgg, N. Fukuma, N. Wakabayashi, Y. Kiso, J. Furmaniak & B. Rees Smith. (1993) Production and Characterisation of a Human Monoclonal Thyroid Peroxidase Autoantibody. Autoimmunity 14:1, pages 1-7.
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Articles from other publishers (18)

R. A. Ajjan & A. P. Weetman. 2018. Thyroid Diseases. Thyroid Diseases 57 87 .
R. A. Ajjan & A. P. Weetman. 2016. Thyroid Diseases. Thyroid Diseases 1 31 .
S M MCLACHLAN & B RAPOPORT. (1995) Genetic and epitopic analysis of thyroid peroxidase (TPO) autoantibodies: markers of the human thyroid autoimmune response. Clinical and Experimental Immunology 101:2, pages 200-206.
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M Liu, L Zhao, Y Gao, Y Huang, G Lu & X Guo. (2012) Epitope recognition patterns of thyroglobulin antibody in sera from patients with Hashimoto's thyroiditis on different thyroid functional status. Clinical and Experimental Immunology 170:3, pages 283-290.
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Eric M. Jacobson, Erlinda Concepcion, Kenneth Ho, Peter Kopp, Jussara Vono Toniolo & Yaron Tomer. (2011) cDNA Immunization of Mice with Human Thyroglobulin Generates Both Humoral and T Cell Responses: A Novel Model of Thyroid Autoimmunity. PLoS ONE 6:4, pages e19200.
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Francesco Latrofa, Debora Ricci, Lucia Grasso, Paolo Vitti, Lucio Masserini, Fulvio Basolo, Clara Ugolini, Giovanni Mascia, Antonio Lucacchini & Aldo Pinchera. (2008) Characterization of Thyroglobulin Epitopes in Patients with Autoimmune and Non-Autoimmune Thyroid Diseases Using Recombinant Human Monoclonal Thyroglobulin Autoantibodies. The Journal of Clinical Endocrinology & Metabolism 93:2, pages 591-596.
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Eric M. Jacobson & Yaron Tomer. (2007) The CD40, CTLA-4, thyroglobulin, TSH receptor, and PTPN22 gene quintet and its contribution to thyroid autoimmunity: Back to the future. Journal of Autoimmunity 28:2-3, pages 85-98.
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Peter BurneSarah MitchellBernard Rees Smith. (2005) Point-of-Care Assays for Autoantibodies to Thyroid Peroxidase and to Thyroglobulin. Thyroid 15:9, pages 1005-1010.
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Sandra M. McLachlan & Basil Rapoport. (2004) Thyroid stimulating monoclonal antibodies: overcoming the road blocks and the way forward. Clinical Endocrinology 61:1, pages 10-18.
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Francesco Latrofa, Pavel Pichurin, Jin Guo, Basil Rapoport & Sandra M. McLachlan. (2003) Thyroglobulin-Thyroperoxidase Autoantibodies Are Polyreactive, Not Bispecific: Analysis Using Human Monoclonal Autoantibodies. The Journal of Clinical Endocrinology & Metabolism 88:1, pages 371-378.
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Maria Pilar Armengol, Manel Juan, Anna Lucas-Martín, María Teresa Fernández-Figueras, Dolores Jaraquemada, Teresa Gallart & Ricardo Pujol-Borrell. (2001) Thyroid Autoimmune Disease. The American Journal of Pathology 159:3, pages 861-873.
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V. ESTIENNE, R.S. McINTOSH, J. RUF, M.S. ASGHAR, P.F. WATSON, P. CARAYON & A.P. WEETMAN. (1998) Comparative Mapping of Cloned Human and Murine Antithyroglobulin Antibodies: Recognition by Human Antibodies of an Immunodominant Region. Thyroid 8:8, pages 643-646.
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Richard Mclntosh, Philip Watson & Anthony Weetman. (1998) Somatic hypermutation in antoimmune thyroid disease. Immunological Reviews 162:1, pages 219-231.
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R.S. McINTOSH & A.P. WEETMAN. (1997) Molecular Analysis of the Antibody Response to Thyroglobulin and Thyroid Peroxidase. Thyroid 7:3, pages 471-487.
Crossref
Takashi Misaki, Mohammad S. Alam, Harumi Sakahara, Kanji Kasagi & Junji Konishi. (1997) Binding of a human monoclonal antithyroglobulin antibody to cultured human thyroid cancer cells. Annals of Nuclear Medicine 11:2, pages 81-85.
Crossref
Basil Rapoport, Stefano Portolano & Sandra M. McLachlan. (1995) Combinatorial libraries: new insights into human organ-specific autoantibodies. Immunology Today 16:1, pages 43-49.
Crossref
Brian R. Champion, Anne Cooke & David C. Rayner. (1992) Thyroid autoimmunity. Current Opinion in Immunology 4:6, pages 770-778.
Crossref
Majida Bouanani, Véronique Hanin, Madeleine Bastide & Bernard Pau. (1992) New antigenic clusters on human thyroglobulin defined by an expanded panel of monoclonal antibodies. Immunology Letters 32:3, pages 259-264.
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