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Autoimmunity Volume 9, 1991 - Issue 3
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Original Article

Effects of Ginkgolide B, A Platelet-Activating Factor Inhibitor on Insulitis in the Spontaneously Diabetic Bb Rat

Jill C. Becka Department of Medicine, University of Washington, Seattle, WA, 98195
,
Charles J. Goodnera Department of Medicine, University of Washington, Seattle, WA, 98195
,
Cindy Wilsona Department of Medicine, University of Washington, Seattle, WA, 98195
,
Deborah Wilsona Department of Medicine, University of Washington, Seattle, WA, 98195
,
Dave Gliddena Department of Medicine, University of Washington, Seattle, WA, 98195
,
Denis G. Baskina Department of Medicine, University of Washington, Seattle, WA, 98195;b Biological Structure, University of Washington, Seattle, WA, 98195;c Veterans Administration Medical Center, Seattle, WA, 98108
,
Åke Lernmarka Department of Medicine, University of Washington, Seattle, WA, 98195
&
Pierre Braquetd Institut Henri Beaufour, Le Plessis Robinson, France
 show all
Pages 225-235 | Received 05 Sep 1990, Accepted 12 Dec 1990, Published online: 07 Jul 2009

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Dian-Lei Wang, Dai-Yin Peng, Xiu-Hua Tao, Yin Cao, Wei-Dong Chen, Yan Liang, Lin Xie & Xiao-Dong Liu. (2013) The pharmacokinetics and conversion of the lactone to the carboxylate forms of ginkgolide B in rat plasma. Journal of Asian Natural Products Research 15:4, pages 337-343.
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Lance W. Jobe, Roel Ubungen, Charles J. Goodner, Denis G. Baskin, Pierre Braquet & Åke Lernmark. (1993) Protection from Bb Rat Diabetes by the Platelet-Activating Factor Inhibitor BN50730. Autoimmunity 16:4, pages 259-266.
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Lance W. Jobe, Sarah Vertrees, Cindy A. Wilson, Cindy Jacobs, Deborah L. Wilson, Kathleen S. Picha, Paul Bakert & Åke Lernmark. (1992) IN VIVO EFFECTS OF INTERLEUKIN-1/β ON BLOOD LEUKOCYTES IN BB RATS PRONE OR RESISTANT TO DIABETES. Autoimmunity 11:4, pages 233-237.
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Articles from other publishers (20)

Weile Ye, Jiaojiao Wang, Peter J. Little, Jiami Zou, Zhihua Zheng, Jing Lu, Yanjun Yin, Hao Liu, Dongmei Zhang, Peiqing Liu, Suowen Xu, Wencai Ye & Zhiping Liu. (2024) Anti-atherosclerotic effects and molecular targets of ginkgolide B from Ginkgo biloba. Acta Pharmaceutica Sinica B 14:1, pages 1-19.
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Xiaowei Zhang, Xinpeng Diao, Luya Li, Yuqian Zhang, Man Liao, Guohua Zhang & Lantong Zhang. (2022) Identification of metabolites of Ginkgolide B in vivo and in vitro using ultra‐high‐performance liquid chromatography‐quadrupole time‐of‐flight mass spectrometry. Journal of Separation Science 45:14, pages 2458-2477.
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Marika Bogdani, Linda Faxius, Malin Fex, Anita Ramelius, Anya Wernersson, John P. Mordes, Elizabeth P. Blankenhorn & Åke Lernmark. (2021) The Vbeta13 T Cell Receptor Monoclonal Antibody Reduces Hyaluronan and CD68+, CD3+, and CD8+ Cell Infiltrations to Delay Diabetes in Congenic BB DRLyp/Lyp Rats. Frontiers in Endocrinology 12.
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Yan-Jing Li, Chen-Feng Zhang, Wen-Zhe Huang, Ting Geng, Zhen-Zhong Wang, Bin-Jiang Zhao, Yi-Fei Zhou & Wei Xiao. (2016) Simultaneous determination of ginkgolides A, B and K in human plasma by UPLC-MS/MS and its application to the pharmacokinetic study of Ginkgo Diterpene Lactone Meglumine Injection in humans. Analytical Methods 8:11, pages 2341-2348.
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Xiao-wen Zhou, Zheng Ma, Ting Geng, Zhen-zhong Wang, Gang Ding, Bi Yu-an & Wei Xiao. (2014) Evaluation of in vitro inhibition and induction of cytochrome P450 activities by hydrolyzed ginkgolides. Journal of Ethnopharmacology 158, pages 132-139.
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Y-G Chen, J P Mordes, E P Blankenhorn, H Kashmiri, M L Kaldunski, S Jia, R Geoffrey, X Wang & M J Hessner. (2013) Temporal induction of immunoregulatory processes coincides with age-dependent resistance to viral-induced type 1 diabetes. Genes & Immunity 14:6, pages 387-400.
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Syed Haris Omar. 2013. Natural Products. Natural Products 3697 3741 .
Dian-lei WANG, Yan LIANG, Wei-dong CHEN, Lin XIE, Guang-ji WANG & Xiao-dong LIU. (2008) Identification of ginkgolide B metabolites in urine and rat liver cytochrome P450 enzymes responsible for their formation in vitro. Acta Pharmacologica Sinica 29:3, pages 376-384.
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Shi-hai XIA & Dian-chun FANG. (2007) Pharmacological action and mechanisms of ginkgolide B. Chinese Medical Journal 120:10, pages 922-928.
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Rhonda Geoffrey, Shuang Jia, Anne E. Kwitek, Jeffrey Woodliff, Soumitra Ghosh, Åke Lernmark, Xujing Wang & Martin J. Hessner. (2006) Evidence of a Functional Role for Mast Cells in the Development of Type 1 Diabetes Mellitus in the BioBreeding Rat. The Journal of Immunology 177:10, pages 7275-7286.
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Christine BeetonHeike WulffNathan E. StandiferPhilippe AzamKatherine M. MullenMichael W. PenningtonAaron Kolski-AndreacoEric WeiAlexandra GrinoDebra R. Counts, Ping H. WangChristine J. LeeHealeyBrian S. AndrewsAnanthakrishnan SankaranarayananDaniel HomerickWerner W. RoeckJamshid TehranzadehKimber L. StanhopePavel ZiminPeter J. HavelStephen GriffeyHans-Guenther Knaus, Gerald T. NepomGeorge A. GutmanPeter A. CalabresiK. George Chandy. (2006) Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases. Proceedings of the National Academy of Sciences 103:46, pages 17414-17419.
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Martin J. Hessner, Xujing Wang, Lisa Meyer, Rhonda Geoffrey, Shuang Jia, Jessica Fuller, Ake Lernmark & Soumitra Ghosh. (2004) Involvement of Eotaxin, Eosinophils, and Pancreatic Predisposition in Development of Type 1 Diabetes Mellitus in the BioBreeding Rat. The Journal of Immunology 173:11, pages 6993-7002.
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Ken Karasawa, Ayako Harada, Noriko Satoh, Keizo Inoue & Morio Setaka. (2003) Plasma platelet activating factor-acetylhydrolase (PAF-AH). Progress in Lipid Research 42:2, pages 93-114.
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Yasuo Tanaka, Yasushi Makiyama & Youji Mitsui. (2002) Anti-CD44 Monoclonal Antibody (IM7) Induces Murine Systemic Shock Mediated by Platelet Activating Factor. Journal of Autoimmunity 18:1, pages 9-15.
Crossref
Marsha Grattan, Qing-Sheng Mi, Craig Meagher & Terry L. Delovitch. (2002) Congenic Mapping of the Diabetogenic Locus Idd4 to a 5.2-cM Region of Chromosome 11 in NOD Mice . Diabetes 51:1, pages 215-223.
Crossref
Koltai Matyas, Guinot Philippe, Hosford David & Pierre G. Braquet. 1994. 81 167 .
Helle Markholst, Susan Eastman, Deborah Wilson, Lloyd Fisher & Åke Lernmark. (1993) Decreased weight gain in BB rats before the clinical onset of insulin-dependent diabetes. Diabetes Research and Clinical Practice 21:1, pages 31-38.
Crossref
F. NICOLETTI, P. L. MERONI, R. DIMARCO, S. GRASSO, W. BARCELLINI, M. O. BORGHI, M. LUNETTA, L. MUGHINl, R. MENTA, H. U. SCHORLEMMER & C. ZANUSSI. (2006) The Effects of Deoxyspergualin on the Development of Diabetes in Diabetes‐Prone BB Rats. Scandinavian Journal of Immunology 36:3, pages 415-420.
Crossref
Laura Crisá, John P. Mordes & Aldo A. Rossini. (2009) Autoimmune diabetes mellitus in the BB rat. Diabetes/Metabolism Reviews 8:1, pages 9-37.
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Susan Eastman, Helle Markholst, Deborah Wilson & Åke Lernmark. (1991) Leukocytosis at the onset of diabetes in crosses of inbred BB rats. Diabetes Research and Clinical Practice 12:2, pages 113-123.
Crossref

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