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Autoimmunity Volume 13, 1992 - Issue 4
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Original Article

Reversal of the Abnormal Development of T Cell Subpopulations in the Thymus of Autoimmune MRL-lpr/lpr Mice by a Polyamine Biosynthesis Inhibitor

T. J. Thomas Program in Clinical Pharmacology, Clinical Research Center, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick, NJ, 08903; Department of Medicine, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick, NJ, 08903
,
Uma B. Gunnia Program in Clinical Pharmacology, Clinical Research Center, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick, NJ, 08903
&
Thresia Thomas Environmental and Community Medicine, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick, NJ, 08903
Pages 275-283 | Received 11 Dec 1991, Accepted 08 Jul 1992, Published online: 07 Jul 2009

Citations (11)

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Hui-Chen Hsu, Thresia Thomas, Leonard H. Sigal & T. J. Thomas. (1999) Polyamine-fas Interactions: Inhibition of Polyamine Biosynthesis in MRL-lpr/lpr Mice is Associated with the Up-regulation of fas mRNA in Thymocytes. Autoimmunity 29:4, pages 299-309.
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Hui-Chen Hsu & T. J. Thomas. (1995) Cyclins and Autoimmunity: Cyclin B1 Gene Expression and Restriction Fragment Length Polymorphism in Lupus-Prone Mice. Autoimmunity 22:1, pages 17-26.
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Articles from other publishers (9)

R F Ashman, N Singh & P S Lenert. (2016) Abnormal thymic maturation and lymphoproliferation in MRL-Fas lpr/lpr mice can be partially reversed by synthetic oligonucleotides: implications for systemic lupus erythematosus and autoimmune lymphoproliferative syndrome . Lupus 26:7, pages 734-745.
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Wesley H. Brooks. (2011) Autoimmune Diseases and Polyamines. Clinical Reviews in Allergy & Immunology 42:1, pages 58-70.
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Ricky A. Sharma & Michael J. Browning. (2005) Mechanisms of the self/non-self-survey in the defense against cancer: Potential for chemoprevention?. Critical Reviews in Oncology/Hematology 56:1, pages 5-22.
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Eftim Adhami. (2004) Calculating the etiology of systemic lupus erythematosus. Medical Hypotheses 62:2, pages 237-246.
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Suyun Dong, Han-Ming Shen & Choon-Nam Ong. 2001. Molecular Mechanisms of Metal Toxicity and Carcinogenesis. Molecular Mechanisms of Metal Toxicity and Carcinogenesis 11 20 .
Ulka R. Tipnis. 2000. 117 146 .
Jessica C. A. ter Steege, Wim A. Buurman & Pierre-Philippe Forget. (1997) Spermine Induces Maturation of the Immature Intestinal Immune System in Neonatal Mice. Journal of Pediatric Gastroenterology &amp Nutrition 25:3, pages 332-340.
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Xianghong Luan, Weiguo Zhao, Bysani Chandrasekar & Gabriel Fernandes. (1995) Calorie restriction modulates lymphocyte subset phenotype and increases apoptosis in MRLlpr mice. Immunology Letters 47:3, pages 181-186.
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Harold E. Bays, Carlos Dujovne, Eric J. Lien, Hua Gao, Linda L. Lien, N. Seiler, C. L. Atanassov, Shradha Sinha, Mukta Srivastava, Mark P. Hayes & Kathryn C. ZoonN. Seiler & C. L. Atanassov. 1994. Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques. Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques 87 141 .

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