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Autoimmunity Volume 12, 1992 - Issue 3
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Original Article

Cytokine Expression in Labial Salivary Glands from Patients with Primary Sjöugren's Syndrome

P. Oxholm Division of Oral Pathology, Department of Stomatology, University of California, San Francisco, California, 94143-0424, USA; Laboratory of Medical Immunology TA, Rigshospitalet, State University Hospital, Tagensvej 20, DK-2200, Copenhagen N, Denmark
,
T. E. Daniels Division of Oral Pathology, Department of Stomatology, University of California, San Francisco, California, 94143-0424, USA
&
K. Bendtzen Laboratory of Medical Immunology TA, Rigshospitalet, State University Hospital, Tagensvej 20, DK-2200, Copenhagen N, Denmark
Pages 185-191 | Received 07 Sep 1991, Accepted 07 Jan 1992, Published online: 07 Jul 2009

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Domenico Sambataro, Gianluca Sambataro, Ylenia Dal Bosco & Riccardo Polosa. (2017) Present and future of biologic drugs in primary Sjögren’s syndrome. Expert Opinion on Biological Therapy 17:1, pages 63-75.
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Akiko Yamada, Rieko Arakaki, Yasusei Kudo & Naozumi Ishimaru. (2013) Targeting IL-1 in Sjögren's syndrome. Expert Opinion on Therapeutic Targets 17:4, pages 393-401.
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Chris T Derk. (2005) Sjogren’s syndrome: models of pathogenesis and treatment targets. Expert Opinion on Therapeutic Patents 15:11, pages 1587-1594.
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Birgitte Nauntofte & Anne Marie Pedersen. (2001) Primary Sjögren’s syndrome: oral aspects on pathogenesis, diagnostic criteria, clinical features and approaches for therapy. Expert Opinion on Pharmacotherapy 2:9, pages 1415-1436.
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Di Sun, Michael R. Emmert-Buck & Philip C. Fox. (1998) Differential Cytokine mRNA Expression in Human Labial Minor Salivary Glands in Primary Sjögren's Syndrome. Autoimmunity 28:3, pages 125-137.
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K. Asmussen, V. Andersen, G. Bendixen, K. Bendtzen, J. U. Prause, J. Thorn, A. Wiik & P. Oxholm. (1997) Quantitative Assessment of Clinical Disease Status in Primary Sjögren's Syndrome. Scandinavian Journal of Rheumatology 26:3, pages 197-205.
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Robert I Fox & Argyrios N Theofilopoulos. (1996) Section Reviews: Biologicals & Immunologicals: Sjögren's syndrome: Pathogenesis and prospects for therapy. Expert Opinion on Investigational Drugs 5:9, pages 1127-1153.
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Marco De Carli, Mario M. D'elios, Gianna Zancuoghi, Sergio Romagnani & Gianfranco Del Prete. (1994) Review Human Th1 and Th2 Cells: Functional Properties, Regulation of Development and Role in Autoimmunity. Autoimmunity 18:4, pages 301-308.
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Harim T. dos Santos, Kihoon Nam, Diana Gil, Venkata Yellepeddi & Olga J. Baker. (2023) Current experimental methods to investigate the impact of specialized pro-resolving lipid mediators on Sjögren’s syndrome. Frontiers in Immunology 13.
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Harim Tavares dos Santos, Kihoon Nam, Frank Maslow, Bryan Trump & Olga J. Baker. (2022) Specialized pro-resolving receptors are expressed in salivary glands with Sjögren's syndrome. Annals of Diagnostic Pathology 56, pages 151865.
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Sofie L. M Blokland, Christina-Maria Flessa, Joel A. G van Roon & Clio P Mavragani. (2021) Emerging roles for chemokines and cytokines as orchestrators of immunopathology in Sjögren’s syndrome. Rheumatology 60:7, pages 3072-3087.
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Austin K. Mircheff, Yanru Wang, Billy X. Pan, Leili Parsa, Prachi Nandoskar & Chuanqing Ding. (2019) Molecular Evidence for Precursors of Sjögren’s Foci in Histologically Normal Lacrimal Glands. International Journal of Molecular Sciences 20:1, pages 223.
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Jeremy Kiripolsky, Liam G McCabe, Daniel P Gaile & Jill M Kramer. (2017) Myd88 is required for disease development in a primary Sjögren's syndrome mouse model. Journal of Leukocyte Biology 102:6, pages 1411-1420.
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Justin T. Easley, Christina L. M. Maruyama, Ching-Shuen Wang & Olga J. Baker. (2016) AT-RvD1 combined with DEX is highly effective in treating TNF- α -mediated disruption of the salivary gland epithelium . Physiological Reports 4:19, pages e12990.
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Adrianos Nezos & Clio P. Mavragani. 2016. Connective Tissue Disease. Connective Tissue Disease 279 292 .
José C Crispín. (2015) Lessons from Sjögren’s syndrome etiopathogenesis: Novel cellular and molecular targets. World Journal of Immunology 5:3, pages 152.
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Clio P. MavraganiHaralampos M. Moutsopoulos. (2014) Sjögren's Syndrome. Annual Review of Pathology: Mechanisms of Disease 9:1, pages 273-285.
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Y.-H. Shin, E. Namkoong, S. Choi, J.-S. Bae, M. Jin, S.-M. Hwang, R. Arote, S.-Y. Choi & K. Park. (2013) Capsaicin Regulates the NF-κB Pathway in Salivary Gland Inflammation. Journal of Dental Research 92:6, pages 547-552.
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Sabrina Lisi, Margherita Sisto, Massimo D’Amore, Dario Domenico Lofrumento & Domenico Ribatti. (2013) Emerging avenues linking inflammation, angiogenesis and Sjögren’s syndrome. Cytokine 61:3, pages 693-703.
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Lucas T. Woods, Jean M. Camden, Josef M. BatekMichael J. Petris, Laurie Erb & Gary A. Weisman. (2012) P2X7 receptor activation induces inflammatory responses in salivary gland epithelium. American Journal of Physiology-Cell Physiology 303:7, pages C790-C801.
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Toshiharu Hayashi. (2011) Dysfunction of Lacrimal and Salivary Glands in Sjögren's Syndrome: Nonimmunologic Injury in Preinflammatory Phase and Mouse Model. Journal of Biomedicine and Biotechnology 2011, pages 1-15.
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Michael Gröschl. (2009) The physiological role of hormones in saliva. BioEssays 31:8, pages 843-852.
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Masahiro Sekiguchi, Tsuyoshi Iwasaki, Masayasu Kitano, Hideki Kuno, Naoaki Hashimoto, Yutaka Kawahito, Masayuki Azuma, Timothy Hla & Hajime Sano. (2008) Role of Sphingosine 1-Phosphate in the Pathogenesis of Sjögren’s Syndrome. The Journal of Immunology 180:3, pages 1921-1928.
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Monica Ek, Karin Popovic, Helena Erlandsson Harris, Cecilia Söderberg Nauclér & Marie Wahren-Herlenius. (2006) Increased extracellular levels of the novel proinflammatory cytokine high mobility group box chromosomal protein 1 in minor salivary glands of patients with Sjögren's syndrome. Arthritis & Rheumatism 54:7, pages 2289-2294.
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Noriyoshi OGAWA, Kumiko SHIMOYAMA & Takafumi KAWANAMI. (2005) Molecular mechanisms of salivary gland destruction in patients with Sjoegren's syndromeシェーグレン症候群における唾液腺組織障害の分子機構. Japanese Journal of Clinical Immunology 28:1, pages 10-20.
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Noriyoshi Ogawa, Li Ping, Li Zhenjun, Yukiko Takada & Susumu Sugai. (2002) Involvement of the interferon-?-induced T cell-attracting chemokines, interferon-?-inducible 10-kd protein (CXCL10) and monokine induced by interferon-? (CXCL9), in the salivary gland lesions of patients with Sj�gren's syndrome. Arthritis & Rheumatism 46:10, pages 2730-2741.
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Robert I. Fox, Yrjö Konttinen & Abraham Fisher. (2001) Use of Muscarinic Agonists in the Treatment of Sjögren's Syndrome. Clinical Immunology 101:3, pages 249-263.
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Rasmi F Abu-Helu, Ioannis D Dimitriou, Efstathia K Kapsogeorgou, Haralampos M Moutsopoulos & Menelaos N Manoussakis. (2001) Induction of Salivary Gland Epithelial Cell Injury in Sjogren's Syndrome: In Vitro Assessment of T Cell-derived Cytokines and Fas Protein Expression. Journal of Autoimmunity 17:2, pages 141-153.
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V. Magnusson, B. Nakken, A. I. Bolstad & M. E. Alarcón-Riquelme. (2001) Cytokine Polymorphisms in Systemic Lupus Erythematosus and Sjögren's Syndrome. Scandinavian Journal of Immunology 54:1-2, pages 55-61.
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Saskia C A van Blokland, Annet F Wierenga-Wolf, Cornelia G van Helden-Meeuwsen, Hemmo A Drexhage, Herbert Hooijkaas, Joop P van de Merwe & Marjan A Versnel. (2000) Professional Antigen Presenting Cells in Minor Salivary Glands in Sjögren’s Syndrome: Potential Contribution to the Histopathological Diagnosis?. Laboratory Investigation 80:12, pages 1935-1941.
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Rachelle Hecht, Michael Connelly, Luigi Marchetti, William D. Ball & Arthur R. Hand. (2000) Cell death during development of intercalated ducts in the rat submandibular gland. The Anatomical Record 258:4, pages 349-358.
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Michael E. Stern, Roger W. Beuerman, Robert I. Fox, Jianping Gao, Austin K. Mircheff & Stephen C. Pflugfelder. 1998. Lacrimal Gland, Tear Film, and Dry Eye Syndromes 2. Lacrimal Gland, Tear Film, and Dry Eye Syndromes 2 643 651 .
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