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Autoimmunity Volume 15, 1993 - Issue 1
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Original Article

Restoration of An Early, Progressive Defect in Responsiveness to T-Cell Activation in Lupus Mice by Exogenous IL-2

Fang-Ping Huang Department of Immunology, University of Glasgow, Western Infirmary, Glasgow, G11 6NT, UK
&
David I. Stott Department of Immunology, University of Glasgow, Western Infirmary, Glasgow, G11 6NT, UK
Pages 19-29 | Received 25 Jan 1993, Published online: 07 Jul 2009

Citations (13)

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G. Ravel, M. Christ, C. Ruat, R. Burnett & J. Descotes. (2002) EFFECT OF MURINE RECOMBINANT IL-2 ON THE COURSE OF LUPUS-LIKE DISEASE IN (NZB×NZW) F1 Female Mice. Immunopharmacology and Immunotoxicology 24:3, pages 409-421.
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Articles from other publishers (12)

Ming Zhang, Gang Yu, Brian Chan, Joshua T. Pearson, Palaniswami Rathanaswami, John Delaney, Ai Ching Lim, John Babcook, Hailing Hsu & Marc A. Gavin. (2015) Interleukin-21 Receptor Blockade Inhibits Secondary Humoral Responses and Halts the Progression of Preestablished Disease in the (NZB × NZW)F1 Systemic Lupus Erythematosus Model. Arthritis & Rheumatology 67:10, pages 2723-2731.
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Agata Kosmaczewska. (2014) Low-Dose Interleukin-2 Therapy: A Driver of an Imbalance between Immune Tolerance and Autoimmunity. International Journal of Molecular Sciences 15:10, pages 18574-18592.
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Catherine E. Calkins. (2011) Regulatory T cells essential to prevent the loss of self-tolerance in murine models of erythrocyte-specific autoantibody responses. Immunologic Research 51:2-3, pages 134-144.
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Maria Gulinello & Chaim Putterman. (2011) The MRL/lpr Mouse Strain as a Model for Neuropsychiatric Systemic Lupus Erythematosus. Journal of Biomedicine and Biotechnology 2011, pages 1-15.
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Cui-Hong Yang, Lina Tian, Guang-Sheng Ling, Nigel J. Trendell-Smith, Liang Ma, Chi-Kin Lo, David I. Stott, Foo Y. Liew & Fang-Ping Huang. (2008) Immunological mechanisms and clinical implications of regulatory T cell deficiency in a systemic autoimmune disorder: Roles of IL-2 versus IL-15. European Journal of Immunology 38:6, pages 1664-1676.
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John M Petitto, Zhi Huang, Jeannette Lo, Ray D BeckJr.Jr., Craig Rinker & David A Hartemink. (2002) Relationship between the development of autoimmunity and sensorimotor gating in MRL-lpr mice with reduced IL-2 production. Neuroscience Letters 328:3, pages 304-308.
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M L Huggins, F-P Huang, D Xu, G Lindop & D I Stott. (2016) Modulation of autoimmune disease in the MRL-lpr/lpr mouse by IL-2 and TGF-β1 gene therapy using attenuated Salmonella typhimurium as gene carrier. Lupus 8:1, pages 29-38.
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Laszlo G. Radvanyi, Kaliannan Raju, David Spaner, Gordon B. Mills & Richard G. Miller. (1998) Interleukin-2 Reverses the Defect in Activation-Induced Apoptosis in T Cells from AutoimmunelprMice. Cellular Immunology 183:1, pages 1-12.
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M. L. HUGGINS, F-P. HUANG, D. XU, G. LINDOP & D. I. STOTT. (1997) Modulation of the Autoimmune Response in Lupus Mice by Oral Administration of Attenuated Salmonella typhimurium Expressing the IL-2 and TGF-? Genes. Annals of the New York Academy of Sciences 815:1 B-Lymphocytes, pages 499-502.
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F.-P. Huang & D.I. Stott. (2016) Dual inhibitory and stimulatory activities in serum from SLE patients and lupus mice that regulate the proliferation of an IL-2-dependent T cell line. Lupus 4:4, pages 297-303.
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David A. Horwitz & Chaim O. Jacob. 1995. Systemic Lupus Erythematosus. Systemic Lupus Erythematosus 51 70 .
David A. Horwitz & Chaim O. Jacob. (1994) The cytokine network in the pathogenesis of systemic lupus erythematosus and possible therapeutic implications. Springer Seminars in Immunopathology 16:2-3, pages 181-200.
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