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Original Article

Significance of Anti-Eye Muscle Antibody in Patients with Thyroid-Associated Ophthalmopathy by Quantitative Western Blot

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Pages 9-16 | Received 12 Feb 1992, Accepted 20 Jul 1992, Published online: 07 Jul 2009

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Read on this site (4)

K. Gunj, S. Kubota, C. Stolarski, S. Wengrowicz, J. S. Kennerdell & J. R. Wall. (1999) A 63 kDa Skeletal Muscle Protein Associated with Eye Muscle Inflammation in Graves' Disease is Identified as the Calcium Binding Protein Calsequestrin. Autoimmunity 29:1, pages 1-9.
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J. Kiljanski, V. Nebes, J. S. Kennerdell & J. R. Wall. (1996) Graves' hyperthyroidism, ophthalmopathy and pretibial myxedema may be components of a multi-system autoimmune disorder. Orbit 15:3, pages 129-136.
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Jack Wall & John S. Kennerdell. (1995) Conference Proceedings: “Progress in Thyroid-Associated Ophthalmopathy”. Autoimmunity 22:3, pages 191-195.
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Articles from other publishers (14)

Teck Kim KhooRebecca S. Bahn. (2007) Pathogenesis of Graves' Ophthalmopathy: The Role of Autoantibodies. Thyroid 17:10, pages 1013-1018.
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Ponnusamy Saravanan & Colin M. Dayan. (2001) THYROID AUTOANTIBODIES. Endocrinology and Metabolism Clinics of North America 30:2, pages 315-337.
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Anthony P. Weetman, E. Helen Kemp, Jonathan N. Ridgway & Philip F. Watson. 2001. Thyroid Eye Disease. Thyroid Eye Disease 1 20 .
Kemp, Ridgway, Smith, Watson & Weetman. (2001) Autoantibodies to the flavoprotein subunit of succinate dehydrogenase: analysis of specificity in autoimmune thyroid disease. Clinical Endocrinology 53:3, pages 291-299.
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Anthony P. Weetman. 1999. Autoimmune Endocrinopathies. Autoimmune Endocrinopathies 245 270 .
KAZUAKI GUNJI, SUMIHARA KUBOTA, JIL SWANSON, JACEK KILJANSKI, TOMASZ BEDNARCZUK, SYLVIA WENGROWICZ, MARIO SALVI & JACK R. WALL. (1998) Role of the Eye Muscles in Thyroid Eye Disease: Identification of the Principal Autoantigens. Thyroid 8:6, pages 553-556.
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Sumihisa Kubota, Kazuaki Gunji, Carol Stolarski, John S. Kennerdell & Jack R. Wall. (1998) Role of Eye Muscle Antibody Measurement in Diagnosis of Thyroid-Associated Ophthalmopathy: A Laboratory Update. Endocrine Practice 4:3, pages 127-132.
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S. Kubota, K. Gunji, B. A. C. Ackrell, B. Cochran, C. Stolarski, S. Wengrowicz, J. S. Kennerdell, Y. Hiromatsu & J. Wall. (1998) The 64-Kilodalton Eye Muscle Protein Is the Flavoprotein Subunit of Mitochondrial Succinate Dehydrogenase: The Corresponding Serum Antibodies Are Good Markers of an Immune-Mediated Damage to the Eye Muscle in Patients with Graves’ Hyperthyroidism1. The Journal of Clinical Endocrinology & Metabolism 83:2, pages 443-447.
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S. KUBOTA, K. GUNJI, C. STOLARSKI, J.S. KENNERDELL & J. WALL. (1998) Reevaluation of the Prevalences of Serum Autoantibodies Reactive with "64-kd Eye Muscle Proteins" in Patients with Thyroid-Associated Ophthalmopathy. Thyroid 8:2, pages 175-179.
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J. I. Kiljanski, K. Peele, I. Stachura, J. Pickeral, C. Stolarski, J. S. Kennerdell & J. R. Wall. (2014) Antibodies against striated muscle, connective tissue and nuclear antigens in patients with thyroid-associated ophthalmopathy: Should Graves’ disease be considered a collagen disorder?. Journal of Endocrinological Investigation 20:10, pages 585-591.
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A. Barsouk, K. A. Peele, J. Kiljanski, C. Stolarski, V. Nebes, J. S. Kennerdell, R. Volpe & J. R. Wall. (2014) Antibody-dependent cell-mediated cytotoxicity against orbital target cells in thyroid-associated ophthalmopathy and related disorders; close relationship between serum cytotoxic antibodies and parameters of eye muscle dysfunction. Journal of Endocrinological Investigation 19:6, pages 334-341.
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A. BARSOUK, S. WENGROWICZ, D. SCALISE, C. STOLARSKI, V. NEBES, M. SATO & J. R. WALL. (1995) New Assays for the Measurement of Serum Antibodies Reactive with Eye Muscle Membrane Antigens Confirm Their Significance in Thyroid-Associated Ophthalmopathy. Thyroid 5:3, pages 195-200.
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N. Tandon, S. L. Yan, K. Arnold, R. A. Metcalfe & A. P. Weetman. (2008) Immunoglobulin class and subclass distribution of eye muscle and fibroblast antibodies in patients with thyroid‐associated ophthalmopathy. Clinical Endocrinology 40:5, pages 629-639.
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J. R. Wall, H. Triller, A. Boucher, N. F. Bernard, M. Salvi & M. Ludgate. (2014) Antibodies reactive with an intracellular epitope of a recombinant 64 kDa thyroid and eye muscle protein in patients with thyroid autoimmunity and ophthalmopathy. Journal of Endocrinological Investigation 16:11, pages 863-868.
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